Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Contribution of DNA polymerase delta in the leading strand replication in Saccharomyces cerevisiae cells

2015/17/B/NZ1/00850

Keywords:

DNA replication fidelity of DNA replication DNA polymerases

Descriptors:

  • NZ1_1: Molecular biology

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Instytut Biochemii i Biofizyki PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Iwona Fijałkowska 

Number of co-investigators in the project: 4

Call: OPUS 9 - announced on 2015-03-16

Amount awarded: 993 600 PLN

Project start date (Y-m-d): 2016-01-21

Project end date (Y-m-d): 2020-01-20

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Wirówka Eppendorf z rotorem.
  2. Termomixer Eppendorf (2 szt.) (36 000 PLN)
  3. Termocykler.
  4. Wirówka z chłodzeniem Eppendorf z rotorem (36 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  1. Increased contribution of DNA polymerase delta to the leading strand replication in yeast with an impaired CMG helicase complex
    Authors:
    Michal Dmowski, Malgorzata Jedrychowska, Karolina Makiela-Dzbenska, Milena Denkiewicz-Kruk, Sushma Sharma, Andrei Chabes, Hiroyuki Araki, Iwona J. Fijalkowska
    Academic press:
    DNA Repair (rok: 2022, tom: 110, strony: 103272), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.dnarep.2022.103272 - link to the publication
  2. Impairment of the non-catalytic subunit Dpb2 of DNA Pol ɛ results in increased involvement of Pol δ on the leading strand
    Authors:
    Michal Dmowski, Karolina Makiela-Dzbenska, Sushma Sharma, Andrei Chabes, Iwona J. Fijalkowska
    Academic press:
    DNA Repair (rok: 2023, tom: 129, strony: 103541), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.dnarep.2023.103541 - link to the publication
  3. Mutation spectrum data for Saccharomyces cerevisiae psf1-1 pol2-M644G mutants
    Authors:
    Michal Dmowski, Karolina Makiela-Dzbenska, Malgorzata Jedrychowska, Milena Denkiewicz-Kruk, Iwona J. Fijalkowska
    Academic press:
    Data in Brief (rok: 2022, tom: 42, strony: 108223), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.dib.2022.108223 - link to the publication

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