Projects funded by the NCN
Embryotoxicity and teratogenicity as a result of response to DNA damage in iPS cells: the effect of methylmercury chloride and low oxygen conditions
2015/17/N/NZ7/04096
Keywords:
embryotoxicity teratogenicity ethical model in vitro embrotoxicity testing human embrio im vitro model human induced pluripotent stem cells DNA damage DNA damage resposne HIF1 alpha methylmercury chloride
Descriptors:
- NZ7_15: Toxicology
- NZ3_8: Stem cell biology
- NZ7_2: Environment and health risks
Panel:
NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology
Host institution :
Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN
woj. mazowieckie
Principal investigator (from the host institution):
Number of co-investigators in the project: 2
Call: PRELUDIUM 9 - announced on 2015-03-16
Amount awarded: 150 000 PLN
Project start date (Y-m-d): 2016-03-24
Project end date (Y-m-d): 2020-09-23
Project duration:: 54 months (the same as in the proposal)
Project status: Project settled
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (1)
- Oxygen as an important factor modulating in vitro MeHgCl toxicity associated with mitochondrial genes in hiPSCsAuthors:J. Augustyniak, G. Lipka, H. Kozlowska, F. Caloni, L. Buzanska,Academic press:Ecotoxicology and Environmental Safety (rok: 2022, tom: Volume 241, strony: 0147-6513), Wydawca: ElsevierStatus:PublishedDOI:10.1016/j.ecoenv.2022.113737 - link to the publication