Sensitization of cancer cells to chemotherapy by novel DNA repair inhibitors
2013/11/B/NZ7/01340
Keywords
Descriptors
- NZ7_14: Farmacja, farmakoterapia, farmakologia
Panel
NZ7 – Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology
Host institution
Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska
Voivodeship: łódzkie
Principal investigator (from the host institution)
Number of co-investigators in the project: 5
Call
OPUS 6 – announced on 2013-09-16
- Amount awarded
- 280 000 PLN
- Project start date
- 2014-07-30
- Project end date
- 2017-07-29
- Project duration
- 36 months (the same as in the proposal)
- Project status
- Project settled
Equipment purchased [PL]
- Inkubator CO2.
- Wirówka z chłodzeniem. Cost: 20 000 PLN
Information in the final report
Publication in academic press/journals (4)
-
DNA Double Strand Breaks Repair Inhibitors: Relevance as Potential New Anticancer Therapeutics
- Authors:
- Paulina Kopa, Anna Macieja, Grzegorz Galita, Zbigniew J. Witczak and Tomasz Poplawski
- Academic press:
- Current Medicinal Chemistry (year: 2018, volume: 25, pages: 46033), Publisher: Benthamscience
- Status:
- Published
- DOI:
- 10.2174/0929867325666180214113154 – link to the publication
-
DNA double-strand breaks repair inhibitors potentiates the combined effect of VP-16 and CDDP in human colorectal adenocarcinoma (LoVo) cells
- Authors:
- Paulina Kopa, Anna Macieja, Elzbieta Pastwa, Ireneusz Majsterek, Tomasz Poplawski
- Academic press:
- Molecular Biology Reports (year: 2021, volume: Online, pages: 46034), Publisher: Springer
- Status:
- Published
- DOI:
- 10.1007/s11033-020-06124-9 – link to the publication
-
Comparison of the effect of three different topoisomerase II inhibitors combined with cisplatin in human glioblastoma cells sensitized with double strand break repair inhibitors
- Authors:
- Anna Macieja, Paulina Kopa, Grzegorz Galita, Elżbieta Pastwa, Ireneusz Majsterek,Tomasz Poplawski
- Academic press:
- Molecular Biology Reports (year: 2019, volume: 46, pages: 3625–3636), Publisher: Springer
- Status:
- Published
- DOI:
- 10.1007/s11033-019-04605-0 – link to the publication
-
Inhibition of DNA‑PK potentiates the synergistic effect of NK314 and etoposide combination on human glioblastoma cells
- Authors:
- Paulina Kopa, Anna Macieja, Izabela Gulbas, Elzbieta Pastwa, Tomasz Poplawski
- Academic press:
- Molecular Biology Reports (year: 2019, volume: 47, pages: 67-76), Publisher: Springer
- Status:
- Published
- DOI:
- 10.1007/s11033-019-05105-x – link to the publication