Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The CMGE helicase-polimerase complex a factor integrating the regulation of cell cyle progression and DNA replication

2017/26/M/NZ3/01044

Keywords:

DNA replication Helicase DNA polymerase epsilon G1/S transition transcription mRNA sequencing

Descriptors:

  • NZ3_1: Cell biology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Michał Dmowski 

Number of co-investigators in the project: 4

Call: HARMONIA 9 - announced on 2017-06-14

Amount awarded: 1 288 000 PLN

Project start date (Y-m-d): 2018-05-18

Project end date (Y-m-d): 2023-05-17

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Brak.

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (1)
  1. Defects in the GINS complex increase the instability of repetitive sequences via a recombination-dependent mechanism
    Authors:
    Malgorzata Jedrychowska, Milena Denkiewicz-Kruk, Malgorzata Alabrudzinska, Adrianna Skoneczna, Piotr Jonczyk, Michal Dmowski, Iwona J. Fijalkowska
    Academic press:
    PLOS GENETICS (rok: 2019, tom: 15-12, strony: e1008494), Wydawca: Public Library of Science
    Status:
    Published
    DOI:
    10.1371/journal.pgen.1008494 - link to the publication
  2. Recombination and Pol ζ Rescue Defective DNA Replication upon Impaired CMG Helicase—Pol ε Interaction
    Authors:
    Milena Denkiewicz-Kruk, Malgorzata Jedrychowska, Shizuko Endo, Hiroyuki Araki, Piotr Jonczyk, Michal Dmowsk, Iwona J. Fijalkowska
    Academic press:
    International Journal of Molecular Sciences (rok: 2020, tom: 21(24), strony: ijms21249484), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms21249484 - link to the publication
  1. The non-catalytic components of the CMGE complex and their influence on genome stability
    Authors:
    M. Dmowski, M. Jędrychowska, N. Talarek, P. Jonczyk, E. Schwob, I. J. Fijałkowska
    Conference:
    44th FEBS Congress (rok: 2019, ), Wydawca: FEBS Open Bio
    Data:
    konferencja 6-11 lipca
    Status:
    Published

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