The CMGE helicase-polimerase complex a factor integrating the regulation of cell cyle progression and DNA replication
2017/26/M/NZ3/01044
Keywords
Descriptors
- NZ3_1: Biologia komórki
Panel
NZ3 – Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology
Host institution
Instytut Biochemii i Biofizyki PAN
Voivodeship: mazowieckie
Principal investigator (from the host institution)
Number of co-investigators in the project: 4
Call
HARMONIA 9 – announced on 2017-06-14
- Amount awarded
- 1 288 000 PLN
- Project start date
- 2018-05-18
- Project end date
- 2023-05-17
- Project duration
- 60 months (the same as in the proposal)
- Project status
- Project settled
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Equipment purchased [PL]
- Brak.
Information in the final report
Publication in academic press/journals (2)
-
Defects in the GINS complex increase the instability of repetitive sequences via a recombination-dependent mechanism
- Authors:
- Malgorzata Jedrychowska, Milena Denkiewicz-Kruk, Malgorzata Alabrudzinska, Adrianna Skoneczna, Piotr Jonczyk, Michal Dmowski, Iwona J. Fijalkowska
- Academic press:
- PLOS GENETICS (year: 2019, volume: 15-12, pages: e1008494), Publisher: Public Library of Science
- Status:
- Published
- DOI:
- 10.1371/journal.pgen.1008494 – link to the publication
-
Recombination and Pol ζ Rescue Defective DNA Replication upon Impaired CMG Helicase—Pol ε Interaction
- Authors:
- Milena Denkiewicz-Kruk, Malgorzata Jedrychowska, Shizuko Endo, Hiroyuki Araki, Piotr Jonczyk, Michal Dmowsk, Iwona J. Fijalkowska
- Academic press:
- International Journal of Molecular Sciences (year: 2020, volume: 21(24), pages: ijms21249484), Publisher: MDPI
- Status:
- Published
- DOI:
- 10.3390/ijms21249484 – link to the publication
Articles in post-conference publications (1)
-
The non-catalytic components of the CMGE complex and their influence on genome stability
- Authors:
- M. Dmowski, M. Jędrychowska, N. Talarek, P. Jonczyk, E. Schwob, I. J. Fijałkowska
- Conference:
- 44th FEBS Congress (year: 2019, pages: P-10-013 160), Publisher: FEBS Open Bio
- Date:
- conference 6-11 lipca
- Status:
- Published