Projects funded by the NCN

The two are better than one - biferrocenyl ROS generators as intelligent anticancer agents

Call: OPUS 27 , Panel: ST5

Principal investigator: prof. Konrad Maciej Kowalski

Uniwersytet Łódzki

Development and characterization of novel multitargeted organometallic tubulin polymerization inhibitors for enhancing t...

Call: OPUS 27 , Panel: NZ7

Principal investigator: dr hab. Damian Nestor Plażuk

Uniwersytet Łódzki

Potential pharmacological strategies aimed at alleviating cognitive dysfunctions accompanying oncological therapy while ...

Call: OPUS 26 , Panel: NZ5

Principal investigator: dr hab. Joanna Monika Wierońska

Instytut Farmakologii PAN

Tumor viscoelasticity as a central player in glioblastoma treatment - towards mechanopharmacology

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr hab. Katarzyna Pogoda

Instytut Fizyki Jądrowej im. Henryka Niewodniczańskiego PAN

Integrated multi-omics approach to accelerate anticancer drug discovery by targeting metabolic reprogramming in human co...

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr hab. Danuta Dudzik

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

Functional and structural analysis of anticancer drugs as protein biosynthesis inhibitors

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr hab. Witold Szaflarski

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Medyczny

Design and microfluidic synthesis of hybrid nanocarriers stabilized by novel sugar surfactants as a potential anticancer...

Call: SONATA BIS 13 , Panel: ST4

Principal investigator: dr hab. Urszula Jolanta Bazylińska

Politechnika Wrocławska

Design and Development of Serine Hydroxymethyltransferase-2 (SHMT2) Inhibitors Blocking Tumor Growth

Call: SONATA BIS 13 , Panel: NZ7

Principal investigator: dr hab. Miłosz Ruszkowski

Instytut Chemii Bioorganicznej PAN

Three to tango - biomaterials with therapeutic and regenerative multifunctionality

Call: SONATA BIS 13 , Panel: ST11

Principal investigator: dr Marzena Krystyna Fandzloch

Instytut Niskich Temperatur i Badań Strukturalnych im. Włodzimierza Trzebiatowskiego PAN

Compounds modulating function of telomeric proteins TRF1 and TRF2

Call: OPUS 25 , Panel: NZ7

Principal investigator: prof. Maciej Wojciech Bagiński

Politechnika Gdańska, Wydział Chemiczny

In vitro anticancer screening of triterpene saponins isolated from beetroot (Beta vulgaris L.) by countercurrent chromat...

Call: PRELUDIUM 22 , Panel: NZ9

Principal investigator: Anna Maria Tekieli

Politechnika Krakowska im. Tadeusza Kościuszki, Wydział Inżynierii i Technologii Chemicznej

Anticancer potential of TMPyP4 porphyrin in breast cancer photodynamic therapy and evaluation of the treatment safety

Call: OPUS 25 , Panel: NZ7

Principal investigator: prof. Błażej Rubiś

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Chiral hybrids of quinones and quinols with double anticancer and antimicrobial activity against drug-resistant pathogen...

Call: OPUS 25 , Panel: NZ7

Principal investigator: prof. Ryszard Józef Ostaszewski

Instytut Chemii Organicznej Polska Akademia Nauk

Myeloid cell subpopulations as a source of effector cells for anticancer therapies using CAR chimeric receptors

Call: OPUS 25 , Panel: NZ6

Principal investigator: dr hab. Angelika Muchowicz

Warszawski Uniwersytet Medyczny, Wydział Lekarski

Preparation and investigation of the biologically active systems with potential anticancer activity, containing P,N-; N,...

Call: SONATA 2 , Panel: NZ7

Principal investigator: dr Monika Richert

Uniwersytet Mikołaja Kopernika w Toruniu

From simple alkaloids to potentially anticancer Ir(III) and Ru(II) complexes supported by the magnetic nanoparticles.

Call: PRELUDIUM 22 , Panel: ST4

Principal investigator: Daria Bogumiła Wojtala

Uniwersytet Wrocławski, Wydział Chemii

Design, Synthesis and Characterization of Functionalized 1,2,4-Trioxanes/Trioxepanes for Antimalarial and Anticancer Use

Call: SONATINA 7 , Panel: NZ7

Principal investigator: dr Mohit Kumar Tiwari

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

CHIRAL RHENIUM AND RHODIUM COMPLEXES OF ANTICANCER AND ANTIBACTERIAL ACTIVITY: SYNTHESIS, ACTIVITY, AND PHYSICOCHEMICAL ...

Call: OPUS 24 , Panel: NZ7

Principal investigator: prof. Jan Czesław Dobrowolski

Narodowy Instytut Leków

Targeted poloxamer micelles with selected drugs as a strategy for overcoming the mechanisms of multidrug resistance in p...

Call: PRELUDIUM BIS 4 , Panel: NZ7

Principal investigator: prof. Tomasz Adam Gośliński

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Exploring the anticancer, antibacterial and antifungal potential and underlying mechanism of action of plants used in Po...

Call: SONATA 18 , Panel: NZ9

Principal investigator: dr Kamila Jadwiga Rachwał

Uniwersytet Przyrodniczy w Lublinie

Targeted drug delivery systems - synthesis and functionalization of nanocarriers

Call: SONATA 2 , Panel: ST5

Principal investigator: dr Krzysztof Szczepanowicz

Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

Fungal bioactive substances with targeted pro-health potential - the role ofinteractions, bioavailability and bioavailab...

Call: OPUS 23 , Panel: NZ9

Principal investigator: prof. Michał Świeca

Uniwersytet Przyrodniczy w Lublinie, Wydział Nauk o Żywności i Biotechnologii

Anticancer drug candidates from Nostoc edaphicum CCNP1411 and Pseudanabaena galeata CCNP1313 (CYANOCRAB)

Call: OPUS 23 , Panel: NZ9

Principal investigator: prof. Hanna Jurata Mazur-Marzec

Uniwersytet Gdański, Wydział Chemii

Pancreatic cancer oxygenation as a prognostic marker during anticancer therapy

Call: OPUS 23 , Panel: NZ5

Principal investigator: dr Martyna Krzykawska-Serda

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Design, synthesis and in vitro and in vivo studies of anticancer potential of phosphonic and phosphinic analogs of sulfo...

Call: OPUS 2 , Panel: ST5

Principal investigator: prof. Tadeusz Marek Gajda

Politechnika Łódzka, Wydział Chemiczny

Identification of anticancer phytochemicals of dandelion root (Taraxaci radix) based on metabolomics and bioassay-guided...

Call: PRELUDIUM 21 , Panel: NZ9

Principal investigator: Sylwia Irena Pawelec

Instytut Uprawy Nawożenia i Gleboznawstwa - Państwowy Instytut Badawczy

Enzyme Responsive Nanoscale Supramolecular Capsules with Application in Anticancer Drug Delivery

Call: POLONEZ BIS 2 , Panel: ST4

Principal investigator: dr Venkateswarulu Mangili

Uniwersytet im. Adama Mickiewicza w Poznaniu, Centrum Zaawansowanych Technologii

Synthesis, structure analysis, anticancer and antimicrobial activity of new derivatives of salinomycin

Call: SONATA 2 , Panel: ST5

Principal investigator: dr hab. Adam Włodzimierz Huczyński

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

Bioresorbable, electrospun nonwoven as a multi-drug delivery system for a combination glioblastoma therapy

Call: SONATA 17 , Panel: NZ7

Principal investigator: dr Monika Anna Musiał-Kulik

Centrum Materiałów Polimerowych i Węglowych PAN

Search for Inhibitors of Human δ1-Pyrroline-5-Carboxylate Reductase 1 (PYCR1) as Lead Molecules for the Development of N...

Call: OPUS 22 , Panel: NZ7

Principal investigator: dr hab. Miłosz Ruszkowski

Instytut Chemii Bioorganicznej PAN

Heterocyclization of benzenoid ansamycins core as useful strategy for designing anticancer agents

Call: PRELUDIUM 20 , Panel: ST4

Principal investigator: Natalia Anna Skrzypczak

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

Anticancer activity of novel derivatives of 9,10-Anthraquinone Dithiocarbamates

Call: PRELUDIUM 20 , Panel: NZ7

Principal investigator: Natalia Anna Maciejewska

Politechnika Gdańska

Evaluation of NOTCH1- and NOTCH3-dependent anticancer drug resistance in a 2D and 3D model of Head and Neck Squamous Cel...

Call: PRELUDIUM 20 , Panel: NZ5

Principal investigator: dr Joanna Elżbieta Kałafut

Uniwersytet Medyczny w Lublinie

Switchable with visible light cisplatin analogs and complexes of selected transition metals - photochemical and anticanc...

Call: OPUS 21 , Panel: NZ7

Principal investigator: prof. Krzysztof Szczubiałka

Uniwersytet Jagielloński, Wydział Chemii

Mitochondria-targeting conjugates as a new anticancer agents

Call: OPUS 21 , Panel: ST4

Principal investigator: prof. Adam Włodzimierz Huczyński

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

Development of new implantable drug forms, biodegradable nanofibers containing selected betulin derivatives in order to ...

Call: OPUS 21 , Panel: NZ7

Principal investigator: prof. Janusz Edward Kasperczyk

Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Farmaceutycznych w Sosnowcu

Thrombin binding aptamer with expanded chemical diversity as potential anticoagulant and anticancer agent

Call: OPUS 21 , Panel: NZ7

Principal investigator: dr Weronika Paulina Kotkowiak

Instytut Chemii Bioorganicznej PAN

Reversible senescence as a new mechanism of cancer cell resistance for chemotherapy. Analysis of the mechanism of cancer...

Call: SONATINA 5 , Panel: NZ3

Principal investigator: dr Karolina Anna Staniak

Politechnika Warszawska, Wydział Chemiczny

Preparation and evaluation of biological activity of new biotinylated hop flavonoid analogues.

Call: SONATA 16 , Panel: NZ9

Principal investigator: dr hab. Monika Stompor-Gorący

Uniwersytet Rzeszowski

Effects of receptor action of L- and D-Lactate on cervical cancer cells. Lactate modulation of cell DNA repair response ...

Call: OPUS 2 , Panel: NZ4

Principal investigator: dr Waldemar Wagner

Instytut Biologii Medycznej PAN

The use of iodoquinolines for biostimulation and biofortification of selected vegetables in iodine and investigation of ...

Call: OPUS 19 , Panel: NZ9

Principal investigator: dr hab. Aneta Agnieszka Koronowicz

Uniwersytet Rolniczy im. Hugona Kołłątaja w Krakowie, Wydział Biotechnologii i Ogrodnictwa

Increasing the precision of chimeric antigen receptor (CAR)-mediated anticancer immunotherapy by using the chemokine-ind...

Call: OPUS 19 , Panel: NZ6

Principal investigator: dr hab. Radosław Zagożdżon

Warszawski Uniwersytet Medyczny

Photodynamic therapy combined with PD-1/PD-L1 blockade immunotherapy: new possibilities for the treatment of immunogenic...

Call: OPUS 19 , Panel: NZ7

Principal investigator: dr hab. Janusz Marcin Dąbrowski

Uniwersytet Jagielloński, Wydział Chemii

DNA polymerase θ as a novel therapeutic target in personalized anticancer therapy

Call: OPUS 19 , Panel: NZ7

Principal investigator: prof. Tomasz Adam Śliwiński

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Tyrosine-modified polyethylenimine polymers as a promising vectors for siRNA delivery in synergistic cancer immunotherap...

Call: PRELUDIUM 19 , Panel: NZ5

Principal investigator: Małgorzata Kubczak

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Foldback triplex-forming oligonucleotides as novel tools for G-quadruplex unfolding and selective inhibition of c-Myc on...

Call: OPUS 19 , Panel: NZ7

Principal investigator: prof. Anna Pasternak

Instytut Chemii Bioorganicznej PAN

Investigation on PD-L1 biology for precise shaping of anticancer adoptive therapies

Call: SONATA 15 , Panel: NZ6

Principal investigator: dr Agnieszka Graczyk-Jarzynka

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Novel bispecific G-quadruplex conjugates as potential anticancer agents

Call: PRELUDIUM 18 , Panel: NZ7

Principal investigator: dr Carolina Sofia Pereira Roxo

Instytut Chemii Bioorganicznej PAN

Lactoferrin and versatile polymers as a tool for selective and targeted delivery of anticancer hydrophobic drugs in the ...

Call: PRELUDIUM 18 , Panel: NZ7

Principal investigator: Przemysław Krzysztof Gajda-Morszewski

Uniwersytet Jagielloński, Wydział Chemii

Synthesis and characterization of new functional coordination compounds of silver(I)

Call: SONATA 15 , Panel: ST5

Principal investigator: dr Sabina Weronika Jaros

Uniwersytet Wrocławski, Wydział Chemii