Projects funded by the NCN

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250 projects found matching your search criteria :

  1. Development of Molecular and Supramolecular Tools to Exploit Human Copper(I) Homeostasis for Cancer Therapeutics

    Call: SONATA BIS 15 , Panel: ST5

    Principal investigator: dr JEENA Manayath Thekkeyil

    Instytut Chemii Fizycznej Polskiej Akademii Nauk

  2. The application of non-covalent and electrostatic interactions in the design ofhelical oligomers to disrupt bacterial ce...

    Call: OPUS 29 , Panel: ST5

    Principal investigator: dr hab. Karolina Agnieszka Pułka-Ziach

    Uniwersytet Warszawski

  3. Determination of the molecular mechanism of BbKI peptide in regulating tissue sensitivity to insulin

    Call: PRELUDIUM 24 , Panel: NZ4

    Principal investigator: Nataniel Jan Stefanowski

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  4. Catalysis of amide bond formation by enzyme-like miniproteins towards a novel method of peptide ligation

    Call: OPUS 29 , Panel: ST5

    Principal investigator: prof. Łukasz Berlicki

    Politechnika Wrocławska

  5. Surface-functionalized lipid-based nonlamellar nanoparticles as carriers for peptide antibiotics.

    Call: OPUS 29 , Panel: ST4

    Principal investigator: dr hab. Ewa Nazaruk

    Uniwersytet Warszawski

  6. Identification of proteolytic cleavage sites in peptide substrates using coarse-grained docking and machine learning met...

    Call: OPUS 29 , Panel: NZ1

    Principal investigator: dr hab. Michał Koliński

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  7. Structural engineering of cell-penetrating peptides into biostable antibacterials to combat drug-resistant pathogens

    Call: OPUS 29 , Panel: NZ1

    Principal investigator: prof. Joanna Dominika Trylska

    Uniwersytet Warszawski

  8. Development and study of peptide inhibitors of membrane fusion in flaviviruses, based on the STEM region of the tick-bor...

    Call: PRELUDIUM 24 , Panel: NZ6

    Principal investigator: Krzysztof Polaczek

    Uniwersytet Gdański

  9. Dynamic RNA structures including pseudoknots and G-quadruplexes of influenza type A virus RNAs as targets for designing ...

    Call: SHENG 4 , Panel: NZ1

    Principal investigator: prof. Elżbieta Beata Kierzek

    Instytut Chemii Bioorganicznej PAN

  10. Mimicking bone chemistry within injectable bone-filler: highly improved bioactivity for faster small defect regeneration

    Call: WEAVE-UNISONO , Panel: ST5

    Principal investigator: dr hab. Aneta Szymańska

    Uniwersytet Gdański

  11. Multilayered polyhydroxyalkanoate-based dressing with sequential degradation for targeted cell chemoattraction and M2 ma...

    Call: OPUS 28 (LAP) , Panel: ST8

    Principal investigator: prof. Sylwia Anna Rodziewicz-Motowidło

    Uniwersytet Gdański

  12. Spina Bifida Polymeric Advanced Regeneration for Cartilage

    Call: OPUS 28 (LAP) , Panel: ST11

    Principal investigator: dr Małgorzata Anna Gazińska

    Politechnika Wrocławska

  13. Gliadin deamidation by bacterial transglutaminases: significance in the pathogenesis of celiac disease.

    Call: SONATA 20 , Panel: NZ7

    Principal investigator: dr Eva Krzyżewska-Dudek

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  14. The first antibody-drug conjugates for Alzheimer's disease therapy

    Call: SONATA BIS 14 , Panel: NZ5

    Principal investigator: dr hab. Marcin Łukasz Poręba

    Politechnika Wrocławska

  15. Frog skin derived cyclic peptide as a molecular scaffold to create a novel tool for combining visualization and inhibiti...

    Call: PRELUDIUM 23 , Panel: ST5

    Principal investigator: Aleksandra Dorota Helbik-Maciejewska

    Uniwersytet Gdański

  16. Proteomic analysis of animal by-products focused on the identification of specific peptide markers

    Call: OPUS 27 , Panel: NZ9

    Principal investigator: dr hab. Anna Maria Stachniuk

    Uniwersytet Medyczny w Lublinie

  17. New Insight into the Mechanism of Action of Antibiotic Peptides - The Role of the Electric Double Layer

    Call: OPUS 27 , Panel: ST4

    Principal investigator: prof. Sławomir Marcin Sęk

    Uniwersytet Warszawski

  18. Search for new biomarkers useful in the diagnosis of adrenal tumors based on the analysis of selected metabolomic profil...

    Call: PRELUDIUM 23 , Panel: NZ5

    Principal investigator: Alicja Duquenne

    CENTRUM MEDYCZNE KSZTAŁCENIA PODYPLOMOWEGO

  19. Peptide-based point-of-care sensor for biomarkers of neurodegenerative conditions

    Call: OPUS 27 , Panel: ST4

    Principal investigator: prof. Anders Martin Jönsson-Niedziółka

    Instytut Chemii Fizycznej Polskiej Akademii Nauk

  20. Digital manufacturing of porous functionally graded hydrogels bearing function-encoding peptides

    Call: PRELUDIUM 23 , Panel: ST5

    Principal investigator: Maria Celeste Tirelli

    Instytut Chemii Fizycznej Polskiej Akademii Nauk

  21. Development and evaluation of a new type of wound healing stimulators based on binding loops of the PDGF and VEGF growth...

    Call: SONATA 19 , Panel: NZ7

    Principal investigator: dr Przemysław Karpowicz

    Uniwersytet Gdański, Wydział Chemii

  22. Platelet-derived growth factor (PDGF-BB) and its peptide derivative as factors increasing cell activity for use in diabe...

    Call: SONATA 19 , Panel: NZ3

    Principal investigator: dr Milena Deptuła

    Gdański Uniwersytet Medyczny, Wydział Lekarski

  23. Effect of phosphorylation of Aβ peptides on the redox activity oftheir copper complexes and aggregation in the context o...

    Call: SONATA 19 , Panel: ST4

    Principal investigator: dr Nina Ewa Wezynfeld

    Politechnika Warszawska, Wydział Chemiczny

  24. Retro-inverso modification of zinc(II)–GLP-1 receptor agonist complexes – from bioinorganic chemistry to animal studies...

    Call: OPUS 26 , Panel: ST5

    Principal investigator: dr hab. Magdalena Alina Rowińska-Żyrek

    Uniwersytet Wrocławski, Wydział Chemii

  25. Interactions between bacterial liposaccharides and an X" shaped peptide oligomer at interfaces: The X-factor in antimicr...

    Call: SONATA 19 , Panel: ST4

    Principal investigator: dr Magdalena Kinga Włodek

    Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

  26. Metallacarborane-peptide amphiphiles as a new strategy in the fight against multidrug-resistant Gram-negative bacteria

    Call: SONATA 19 , Panel: NZ7

    Principal investigator: dr Krzysztof Konrad Fink

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  27. Macrocyclic peptides for targeting of membrane-anchored serine protease

    Call: PRELUDIUM BIS 5 , Panel: NZ7

    Principal investigator: dr hab. Paulina Maria Kasperkiewicz-Wasilewska

    Politechnika Wrocławska

  28. Development of new antibacterial agents based on lytic enzymes produced by bacteriophages

    Call: SONATA BIS 13 , Panel: NZ1

    Principal investigator: dr Monika Wojciechowska

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  29. Novel receptor materials for the construction of a bioelectronic nose for the rapid and efficient detection of lung canc...

    Call: OPUS 25 , Panel: ST5

    Principal investigator: prof. Wojciech Kamysz

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

  30. Peptide-based luminescent coordination capsules and cages – towards bio-inspired cavities illuminated by chiral light

    Call: OPUS 25 , Panel: ST5

    Principal investigator: prof. Agnieszka Szumna

    Instytut Chemii Organicznej Polska Akademia Nauk

  31. The design and development of the peptide inhibitors library targeting Zn(II)-binding site of matrix metalloproteinases ...

    Call: PRELUDIUM 22 , Panel: ST5

    Principal investigator: Paulina Alicja Potok

    Uniwersytet Wrocławski, Wydział Chemii

  32. Computational alchemy and experimental validation: a hybrid approach for designing new antimicrobial peptides

    Call: PRELUDIUM 22 , Panel: NZ1

    Principal investigator: Piotr Maciej Chyży

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  33. Epigenetic biomarkers of destruction of residual beta cells after diagnosis of type 1 diabetes – links to diabetic ketoa...

    Call: PRELUDIUM 22 , Panel: NZ5

    Principal investigator: Arkadiusz Mariusz Michalak

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  34. Conjugates of peptide nucleic acids with aminoglycosides and fluoroquinolones as a novel strategy to target multi-drug r...

    Call: PRELUDIUM 22 , Panel: ST5

    Principal investigator: Izabela Siekierska

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  35. Research on the preparation of new, hydrogel nanosystems for targeted therapy of colorectal cancer

    Call: SONATA 18 , Panel: NZ7

    Principal investigator: dr Urszula Helena Piotrowska

    Warszawski Uniwersytet Medyczny

  36. Retro-inverso strategy as a way to enhance the antimicrobial activity of clavanin complexes

    Call: PRELUDIUM BIS 4 , Panel: ST4

    Principal investigator: dr hab. Magdalena Alina Rowińska-Żyrek

    Uniwersytet Wrocławski, Wydział Chemii

  37. Identification of key structural elements of immunomodulatory proteins - inhibitors of antigenic peptide transporter TAP...

    Call: SONATA 18 , Panel: NZ7

    Principal investigator: dr Natalia Anna Karska

    Uniwersytet Gdański, Wydział Chemii

  38. Biological membranes and macromolecular crowding in the function of the hepatitis C virus proteases

    Call: PRELUDIUM BIS 4 , Panel: NZ1

    Principal investigator: prof. Joanna Dominika Trylska

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  39. Anticancer drug candidates from Nostoc edaphicum CCNP1411 and Pseudanabaena galeata CCNP1313 (CYANOCRAB)

    Call: OPUS 23 , Panel: NZ9

    Principal investigator: prof. Hanna Jurata Mazur-Marzec

    Uniwersytet Gdański, Wydział Oceanografii i Geografii

  40. N-terminally truncated albumin: friend or foe of copper metabolism?

    Call: PRELUDIUM 21 , Panel: ST4

    Principal investigator: Marta Dorota Wiśniewska

    Instytut Biochemii i Biofizyki PAN

  41. Bionanoparticles with a molecular targeting device as a weapon for breast cancer

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: prof. Sylwia Anna Rodziewicz-Motowidło

    Uniwersytet Gdański, Wydział Chemii

  42. Proinsulin C-peptide and G protein-coupled receptor 146 (GPR146) – clinical investigation of the impact of their signall...

    Call: PRELUDIUM 21 , Panel: NZ4

    Principal investigator: Aleksandra Ryk

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  43. Peptide receptor complexes for auxin canalization and regeneration in Arabidopsis.

    Call: OPUS 22 (LAP) , Panel: NZ1

    Principal investigator: dr Ewa Mazur

    UNIWERSYTET ŚLĄSKI, Wydział Nauk Przyrodniczych

  44. The effect of milk-clotting enzymes from Jiuqu microbes on coagulation and quality developing mechanisms of cheese

    Call: OPUS 22 , Panel: NZ9

    Principal investigator: dr hab. Justyna Żulewska

    Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Nauki o Żywności

  45. Blocking interactions between Rab1b and Rab5 proteins and their negative regulators TBC1D20 and TBC1D17 with synthetic p...

    Call: PRELUDIUM BIS 3 , Panel: NZ1

    Principal investigator: dr hab. Edyta Violetta Gendaszewska-Darmach

    Politechnika Łódzka, Wydział Biotechnologii i Nauk o Żywności

  46. SELECTIVE REGULATION OF RAB GTPASES BY TARGETING PROTEIN-PROTEIN INTERACTIONS BETWEEN RABS AND REGULATORY PROTEINS

    Call: PRELUDIUM BIS 3 , Panel: ST4

    Principal investigator: dr hab. Katarzyna Magdalena Błażewska

    Politechnika Łódzka, Wydział Chemiczny

  47. De novo design of cavity-incorporating mini-proteins and their application in catalysis

    Call: OPUS 22 , Panel: ST4

    Principal investigator: prof. Łukasz Berlicki

    Politechnika Wrocławska

  48. Multi-scale method for amyloid fibril assembly using protofilament structures predicted by coarse-grained docking simula...

    Call: OPUS 22 , Panel: NZ2

    Principal investigator: dr Michał Koliński

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  49. New approach to the treatment of Alzheimer's disease targetingresolution of inflammation and modulation of biomechanical...

    Call: OPUS 22 , Panel: NZ4

    Principal investigator: prof. Agnieszka Basta-Kaim

    Instytut Farmakologii PAN

  50. Identification of low molecular weight compounds and peptides with high biological activity present in maggot secretions...

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Katarzyna Joanna Papaj

    Politechnika Śląska, Centrum Biotechnologii

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