Computational alchemy and experimental validation: a hybrid approach for designing new antimicrobial peptides

2023/49/N/NZ1/00989

Keywords

Descriptors

  • NZ1_03: Biofizyka
  • NZ2_10: Modelowanie i symulacje biologiczne
  • ST5_12: Chemia polimerów

Panel

NZ1 – Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

Piotr Maciej Chyży

Number of co-investigators in the project: 2

Call

PRELUDIUM 22 – announced on 2023-03-16

Amount awarded
139 997 PLN
Project start date
2024-01-16
Project end date
2027-01-15
Project duration
36 months (the same as in the proposal)
Project status
Pending project

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (1)

  1. Design, synthesis and evaluation of lysine- and leucine-rich hydrocarbon-stapled peptides as antibacterial agents

    Authors:
    Małgorzata Lobka, Izabela Siekierska, Piotr Chyży, Michał Burmistrz, Julia Macyszyn, Renata Grzela, Monika Wojciechowska, Joanna Trylska
    Academic press:
    European Journal of Medicinal Chemistry (year: 2025, volume: 290, pages: 117445), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ejmech.2025.117445 – link to the publication

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Graphic design and implementation: Jakub Piotrowski