Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Blocking HVEM/LIGHT interactions using peptides - an innovative approach to immunosuppression

2020/39/O/ST4/01379

Keywords:

peptides design HVEM protein LIGHT protein immunosuppression inhibitors molecular modeling ELISA SPR.

Descriptors:

  • ST4_004:
  • NZ1_004:
  • NZ1_001:

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Uniwersytet Gdański, Wydział Chemii

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Adam Kazimierz Sieradzan 

Number of co-investigators in the project: 2

Call: PRELUDIUM BIS 2 - announced on 2020-09-15

Amount awarded: 536 600 PLN

Project start date (Y-m-d): 2021-10-01

Project end date (Y-m-d): 2025-09-30

Project duration:: 48 months (the same as in the proposal)

Project status: Pending project

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (1)
  1. Multilayered Computational Framework for Designing Peptide Inhibitors of HVEM-LIGHT Interaction
    Authors:
    Piotr Ciura, Pamela Smardz, Marta Spodzieja, Adam K. Sieradzan*, Pawel Krupa
    Academic press:
    J. Phys Chem. B (rok: 2024, tom: 128, strony: 6770-6785), Wydawca: ACS Publications
    Status:
    Published
    DOI:
    10.1021/acs.jpcb.4c02255 - link to the publication