Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Rational design and pharmacological characterization of chimeric cyclic opioid peptide analogs targeting multiple receptors

2015/17/B/ST5/00153

Keywords:

peptide synthesis mixed opioid receptors affinity chimeric peptides

Descriptors:

  • ST5_16:

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Anna Janecka 

Number of co-investigators in the project: 5

Call: OPUS 9 - announced on 2015-03-16

Amount awarded: 1 036 560 PLN

Project start date (Y-m-d): 2016-02-24

Project end date (Y-m-d): 2021-02-23

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Flex-Station 3 - czytnik florescencji, absorbancji, luminescencji, TRF, oraz polaryzacji z funkcją pipetowania (390 000 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  1. Design, Synthesis and Functional Analysis of Cyclic Opioid Peptides with Dmt-Tic Pharmacophore.
    Authors:
    Sarkar A, Adamska-Bartlomiejczyk A, Piekielna-Ciesielska J, Wtorek K, Kluczyk A, Borics A, Janecka A.
    Academic press:
    Molecules (rok: 2020, tom: 25(18), strony: 4260-4275), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules25184260 - link to the publication
  2. Synthesis and Pharmacological Evaluation of Hybrids Targeting Opioid and Neurokinin Receptors
    Authors:
    Karol Wtorek, Anna Adamska-Bartłomiejczyk, Justyna Piekielna-Ciesielska, Federica Ferrari, Chiara Ruzza, Alicja Kluczyk, Joanna Piasecka-Zelga, Girolamo Calo', Anna Janecka.
    Academic press:
    Molecules (rok: 2019, tom: 24, strony: 4460), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules24244460 - link to the publication

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