Rational design and pharmacological characterization of chimeric cyclic opioid p

Rational design and pharmacological characterization of chimeric cyclic opioid peptide analogs targeting multiple receptors

2015/17/B/ST5/00153

Keywords

Descriptors

ST5_16: Chemia biologiczna

Panel

ST5 – Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Voivodeship: łódzkie

Other projects carried out by the institution »

Principal investigator (from the host institution)

prof. Anna Ewa Janecka

Number of co-investigators in the project: 5

Call

OPUS 9 – announced on 2015-03-16

Amount awarded: 1 036 560 PLN
Project start date: 2016-02-24
Project end date: 2021-02-23
Project duration: 60 months (the same as in the proposal)
Project status: Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

Flex-Station 3 - czytnik florescencji, absorbancji, luminescencji, TRF, oraz polaryzacji z funkcją pipetowania. Cost: 390 000 PLN

Information in the final report

Publication in academic press/journals (2)

Design, Synthesis and Functional Analysis of Cyclic Opioid Peptides with Dmt-Tic Pharmacophore.

Authors:
Sarkar A, Adamska-Bartlomiejczyk A, Piekielna-Ciesielska J, Wtorek K, Kluczyk A, Borics A, Janecka A.

Academic press:
Molecules (year: 2020, volume: 25(18), pages: 4260-4275), Publisher: MDPI

Status:
Published

DOI:
10.3390/molecules25184260 – link to the publication
Synthesis and Pharmacological Evaluation of Hybrids Targeting Opioid and Neurokinin Receptors

Authors:
Karol Wtorek, Anna Adamska-Bartłomiejczyk, Justyna Piekielna-Ciesielska, Federica Ferrari, Chiara Ruzza, Alicja Kluczyk, Joanna Piasecka-Zelga, Girolamo Calo', Anna Janecka.

Academic press:
Molecules (year: 2019, volume: 24, pages: 4460), Publisher: MDPI

Status:
Published

DOI:
10.3390/molecules24244460 – link to the publication

« New search

Projects search