Search results

1. Design and synthesis of proteolytically stable and cell permeable activators of human 20S proteasome and assessing their…

Principal investigator: dr hab. Elżbieta - Jankowska

Uniwersytet Gdański, Wydział Chemii

Call: PRELUDIUM BIS 1, Panel: NZ7

2. Combined experimental and theoretical studies of the catalytic activity of RPE65 enzyme using biomimetic active centre m…

Principal investigator: dr hab. Adam Maciej Kubas

Instytut Chemii Fizycznej Polskiej Akademii Nauk

Call: OPUS 20, Panel: ST4

3. Synthesis and characterization of new molecular probes for monitoring activity of enzymes associated with RNA decapping …

Principal investigator: dr hab. Joanna Kowalska

Uniwersytet Warszawski, Wydział Fizyki

Call: OPUS 16, Panel: ST5

4. Effect of confinement on the activity of single enzyme molecules encapsulated in liposome structure

Principal investigator: dr Hubert Marek Piwoński

Instytut Chemii Fizycznej Polskiej Akademii Nauk

Call: SONATA 2, Panel: ST4

5. Gene expression, protein concentration and enzymatic activity of redox enzymes in relation to trace element status in li…

Principal investigator: Jakub Piotr Adamus

Warszawski Uniwersytet Medyczny

Call: PRELUDIUM 24, Panel: NZ1

6. Synthesis, characteristics and activity of biopolymer-based modified magnetic nanoparticles as potential carriers for en…

Principal investigator: dr hab. Michał Piotr Marszałł

Uniwersytet Mikołaja Kopernika w Toruniu, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy; Wydział Farmaceutyczny

Call: OPUS 8, Panel: NZ7

7. The use of proteolytic enzymes isolated form nonconventional sources for obtaining biologically active peptides from mil…

Principal investigator: dr Anna Ewa Dąbrowska

Uniwersytet Przyrodniczy we Wrocławiu, Wydział Nauk o Żywności

Call: OPUS 1, Panel: NZ9

8. Reversible modification of enzyme activity and substrate specificity by engineering of the ligand exchange pathways

Principal investigator: dr Artur Wiktor Góra

Politechnika Śląska, Centrum Biotechnologii

Call: HARMONIA 7, Panel: NZ1

9. Mechanisms of cyclization reactions leading to biologically active compounds catalyzed by iron dependent enzymes.

Principal investigator: prof. Tomasz Maciej Borowski

Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

Call: OPUS 23, Panel: ST4

10. Application of lanthanides in activity-based probes for the simultaneous detection of proteolytic enzymes.

Principal investigator: prof. Marcin Drąg

Politechnika Wrocławska

Call: HARMONIA 10, Panel: ST5

11. Plasmonic nanoparticles decorated with fluorescently-labelled mRNA: using single-pair FRET effect for investigating enzy…

Principal investigator: prof. Joanna Niedziółka-Jönsson

Instytut Chemii Fizycznej Polskiej Akademii Nauk

Call: OPUS 25, Panel: ST4

12. Molecular origins of mechanisms governing biological functions of enzymes with buried actives sites: substrate inhibitio…

Principal investigator: dr hab. Jan Brezovsky

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Call: SONATA BIS 7, Panel: NZ1

13. Multicommutated bioanalytical systems for kinetic studies and enzyme activity assays

Principal investigator: prof. Robert Koncki

Uniwersytet Warszawski, Wydział Chemii

Call: OPUS 7, Panel: ST4

14. Role of the gates and anchoring residues in enzymes activity and selectivity.

Principal investigator: dr Artur Wiktor Góra

Politechnika Śląska, Centrum Biotechnologii

Call: SONATA BIS 3, Panel: NZ1

15. Iron enzymes involved in biosynthesis of antibiotics - molecular activity mechanisms

Principal investigator: prof. Ewa Brocławik

POLSKA AKADEMIA UMIEJĘTNOŚCI

Call: OPUS 1, Panel: ST4

16. Unlocking nature's potential - exploring the ability of newly isolated from the environment bacteriophage and its enzyme…

Principal investigator: Aleksandra Łukasiak

Uniwersytet Gdański, Wydział Biologii

Call: PRELUDIUM 22, Panel: NZ9

17. Assessment of changes in mitochondria and the activity of selected enzymes and mitochondrial proteins in freshwater shri…

Principal investigator: Anna - Ostróżka

UNIWERSYTET ŚLĄSKI, Wydział Nauk Przyrodniczych

Call: PRELUDIUM 20, Panel: NZ8

18. Changes of the profile of fruits polyphenolic compounds under the influence of high pressure considering the activity of…

Principal investigator: Justyna Szczepańska

Instytut Biotechnologii Przemysłu Rolno-Spożywczego im. prof. Wacława Dąbrowskiego

Call: PRELUDIUM 17, Panel: NZ9

19. New biocatalytic systems: carbon nanomaterial - enzyme, with controlled activity and potential application in anticancer…

Principal investigator: Paulina Erwardt

Uniwersytet Mikołaja Kopernika, Wydział Chemii

Call: PRELUDIUM 14, Panel: ST5

20. Structure and function of anti-virulent phage origin enzymes active against ESKAPE pathogens

Principal investigator: prof. Zuzanna Drulis-Kawa

Uniwersytet Wrocławski, Wydział Nauk Biologicznych

Call: HARMONIA 9, Panel: NZ1

21. Investigation of the molecular mechanisms of anti-leukemic activity of SK053, a small molecule compound targeting enzyme…

Principal investigator: prof. Dominika Anna Nowis

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Call: SONATA BIS 3, Panel: NZ5

22. Influence of chlorpyrifos on the activity of enzymes responsible for the vitamin D3 synthesis in skin cells

Principal investigator: Krzysztof Bogumił Sawicki

Instytut Medycyny Wsi im. Witolda Chodźki

Call: PRELUDIUM 5, Panel: NZ7

23. 2-Oxoglutarate dependent oxygenases in the biosynthesis of pharmacologically active alkaloids - structure, catalytic mec…

Principal investigator: prof. Tomasz Maciej Borowski

Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

Call: SONATA BIS 4, Panel: NZ1

24. The effects of carbamylation on the activity and biological function of Angiotensin I Converting Enzyme (ACE1)

Principal investigator: Marta Kamińska

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Call: PRELUDIUM 18, Panel: NZ1

25. Impact of high hydrostatic pressure on the profile of bioactive compounds, antioxidant activity, enzyme and microbial st…

Principal investigator: dr hab. Wioletta Błaszczak

Instytut Rozrodu Zwierząt i Badań Żywności PAN

Call: OPUS 9, Panel: NZ9

26. Selective activity based probes for imaging of active serine proteases in neutrophils.

Principal investigator: dr hab. Marcin Drąg

Politechnika Wrocławska, Wydział Chemiczny

Call: HARMONIA 6, Panel: ST5

27. Novel MxOy-lignin hybrid materials as a multifunctional supports in enzyme immobilization process

Principal investigator: Jakub Łukasz Zdarta

Politechnika Poznańska, Wydział Technologii Chemicznej

Call: PRELUDIUM 10, Panel: ST8

28. Development of new antibacterial agents based on lytic enzymes produced by bacteriophages

Principal investigator: dr Monika Wojciechowska

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Call: SONATA BIS 13, Panel: NZ1

29. Study on the kinetics inactivation of selected plant enzymes from oxidoreductase group by using supercritical carbon dio…

Principal investigator: dr Krystian Marcin Marszałek

Instytut Biotechnologii Przemysłu Rolno-Spożywczego im. prof. Wacława Dąbrowskiego

Call: SONATA 9, Panel: NZ9

30. Involvement of vacuolar processing enzyme (VPE) and lipase in the degradation of autophagic bodies in cells embryo axes …

Principal investigator: Szymon Stefaniak

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Call: PRELUDIUM 20, Panel: NZ3

31. Design and synthesis of probes for RabGGTase profiling and their application for identification of the site of phosphono…

Principal investigator: dr hab. Katarzyna Błażewska

Politechnika Łódzka, Wydział Chemiczny

Call: SONATA BIS 4, Panel: ST5

32. Development of One-pot Multienzymatic Cascade Systems for Sustainable Synthesis of Active Pharmaceutical Ingredients

Principal investigator: dr hab. Jakub Łukasz Zdarta

Politechnika Poznańska

Call: SONATA BIS 14, Panel: ST8

33. Dietary polyphenols as thyroid peroxidase (TPO) modulators with multidirectional biological activity - a combined in vit…

Principal investigator: prof. Urszula Katarzyna Gawlik

Uniwersytet Przyrodniczy w Lublinie, Wydział Nauk o Żywności i Biotechnologii

Call: OPUS 17, Panel: NZ9

34. Tick-borne encephalitis virus protease as a molecular target for novel inhibitors and activity-based probes

Principal investigator: dr Renata Grzywa

Politechnika Wrocławska

Call: OPUS 28, Panel: NZ6

35. Search for structure-antimicrobial activity correlation for selected boraheterocycles

Principal investigator: prof. Sergiusz Mariusz Luliński

Politechnika Warszawska, Wydział Chemiczny

Call: OPUS 16, Panel: ST5

36. Investigating the role of human tissue kallikreins in regulating matrix metalloproteinase activity.

Principal investigator: Katherine Monique Falkowski

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Call: PRELUDIUM 12, Panel: NZ1

37. Binding interactions of activators in the bacterial adenylate kinases

Principal investigator: Agnieszka Ludwiczak

Uniwersytet Mikołaja Kopernika, Wydział Chemii

Call: PRELUDIUM 7, Panel: ST4

38. Evaluating the antibacterial activity of the bacteriophage protein targeting Staphylococcus aureus, including drug-resis…

Principal investigator: dr Zuzanna Maria Kaźmierczak

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Call: SONATA 19, Panel: NZ7

39. Optimization of coarse-grained molecular dynamics simulations for tunnel exploration of large proteins with buried activ…

Principal investigator: Nishita Mandal

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Call: PRELUDIUM 22, Panel: NZ2

40. Synthesis of active pharmaceutical ingredients with the use of biocatalysts supported by ionic liquids

Principal investigator: Oliwia Degórska

Politechnika Poznańska, Wydział Technologii Chemicznej

Call: PRELUDIUM 22, Panel: ST8

41. The Power of Hybrid – Development of Novel Multienzymatic Cascade Reactions and Photo-Biocatalytic Redox Systems for Asy…

Principal investigator: dr Paweł Borowiecki

Politechnika Warszawska

Call: OPUS 24, Panel: ST4

42. Role of roots of selected trees species in soil organic matter stabilization and in shaping microbial activity of forest…

Principal investigator: Karolina Staszel-Szlachta

Uniwersytet Rolniczy im. Hugona Kołłątaja w Krakowie, Wydział Leśny

Call: PRELUDIUM 20, Panel: NZ9

43. Chiroptical properties of proteins and their complexes (CRISPR/Cas-RNA), and their relationship to biological activity

Principal investigator: dr Monika Anna Hałat

Uniwersytet Rolniczy im. Hugona Kołłątaja w Krakowie, Wydział Biotechnologii i Ogrodnictwa

Call: SONATINA 5, Panel: ST4

44. Biotechnological potential and antimicrobial activity of biosurfactant-lipase conjugates immobilized on biopolymers

Principal investigator: dr Tomasz Wojciech Janek

Uniwersytet Przyrodniczy we Wrocławiu, Wydział Biotechnologii i Nauk o Żywności

Call: OPUS 19, Panel: NZ9

45. Characterization of hydrolysates and peptides derived from oat kernels proteins in the context of their activity in dise…

Principal investigator: dr Monika Anna Pliszka

Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Nauki o Żywności

Call: PRELUDIUM 16, Panel: NZ9

46. CP protease of the O'nyong-nyong virus: substrate profiling, design and synthesis of inhibitors and activity-based probe…

Principal investigator: dr hab. Marcin Sieńczyk

Politechnika Wrocławska

Call: OPUS 15, Panel: NZ6

47. Factors determining changes in enzymatic activity as well as the functional and genetic diveristy of microorganisms acro…

Principal investigator: prof. Anna Halina Piotrowska-Długosz

Uniwersytet Technologiczno-Przyrodniczy im. Jana i Jędrzeja Śniadeckich w Bydgoszczy, Wydział Rolnictwa i Biotechnologii

Call: OPUS 15, Panel: NZ9

48. New derivatives of clopidogrel - enantioselective biosynthesis and antiplatelet activity in vitro

Principal investigator: Adam Edward Sikora

Uniwersytet Mikołaja Kopernika w Toruniu, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy; Wydział Farmaceutyczny

Call: PRELUDIUM 14, Panel: NZ7

49. Morita-Baylis-Hillman adducts as substrates in the synthesis of biologically active organophosphorus compounds

Principal investigator: dr hab. Artur Jacek Mucha

Politechnika Wrocławska, Wydział Chemiczny

Call: OPUS 5, Panel: ST5

50. The role of the brain serotonergic system in the expression and activity of liver cytochrome P450.

Principal investigator: dr Marta Anna Rysz

Instytut Farmakologii PAN

Call: PRELUDIUM 4, Panel: NZ7

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