Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Investigating the role of human tissue kallikreins in regulating matrix metalloproteinase activity.

2016/23/N/NZ1/01517

Keywords:

enzyme protease proteolysis activation kallikrein matrix metalloproteinase extracellular matrix

Descriptors:

  • NZ1_1: Molecular biology
  • NZ1_2: Biochemistry
  • NZ1_11: Other related subjects

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Katherine Falkowski 

Number of co-investigators in the project: 2

Call: PRELUDIUM 12 - announced on 2016-09-15

Amount awarded: 98 700 PLN

Project start date (Y-m-d): 2017-08-04

Project end date (Y-m-d): 2019-11-03

Project duration:: 27 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (1)
  1. Kallikrein-Related Peptidase 14 Activates Zymogens of Membrane Type Matrix Metalloproteinases (MT-MMPs)—A CleavEx Based Analysis
    Authors:
    Katherine Falkowski, Ewa Bielecka, Ida B. Thøgersen, Oliwia Bocheńska, Karolina Płaza, Magdalena Kalińska, Laura Sąsiadek, Małgorzata Magoch, Aleksandra Pęcak, Magdalena Wiśniewska, Natalia Gruba, Magdalena Wysocka, Anna Wojtysiak, Magdalena Brzezińska-Bodal, Kamila Sychowska, Anastasija Pejkovska, Maren Rehders, Georgina Butler, Christopher M Overall, Klaudia Brix, Grzegorz Dubin, Adam Lesner, Andrzej Kozik, Jan J. Enghild, Jan Potempa and Tomasz Kantyka
    Academic press:
    International Journal of Molecular Sciences (rok: 2020, tom: 21, strony: E4383), Wydawca: MPDI
    Status:
    Published
    DOI:
    10.3390/ijms21124383 - link to the publication