Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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The Power of Hybrid – Development of Novel Multienzymatic Cascade Reactions and Photo-Biocatalytic Redox Systems for Asymmetric Synthesis of Optically Active High-Added Value Compounds ("EnzCasc-Photo4BioCat")

2022/47/B/ST4/00139

Keywords:

Biocatalysis Photoredox Catalysis Biocatalytic Deracemisation Methods Artificial Biocatalytic Linear Cascades Enzymes Alcohol Dehydrogenases Transaminases Acyltransferases Laccases Lipases Aldehyde Oxidases Catalases Optically Pure Compounds Chiral Pharmaceuticals.

Descriptors:

  • ST4_009:
  • ST4_008:
  • ST4_014:

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Politechnika Warszawska

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Paweł Borowiecki 

Number of co-investigators in the project: 7

Call: OPUS 24 - announced on 2022-07-15

Amount awarded: 1 970 910 PLN

Project start date (Y-m-d): 2023-09-01

Project end date (Y-m-d): 2026-09-30

Project duration:: 37 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (2)
  1. One-Pot Sequential Two-Step Photo-Biocatalytic Deracemization of sec-Alcohols Combining Photocatalytic Oxidation and Bioreduction
    Authors:
    Aleksandra Rudzka, Natalia Antos, Tamara Reiter, Wolfgang Kroutil, Paweł Borowiecki
    Academic press:
    ACS Catalysis (rok: 2024, tom: 14, strony: 1808–1823), Wydawca: ACS Publications
    Status:
    Published
    DOI:
    10.1021/acscatal.3c05100 - link to the publication
  2. ADH-Catalyzed Biooxidation of (Hetero)aromatic sec-Alcohols to Ketones Employing Vinyl Acetate as Acetaldehyde Surrogate
    Authors:
    Aleksandra Rudzka, Tamara Reiter, Wolfgang Kroutil, Paweł Borowiecki
    Academic press:
    ChemCatChem (rok: 2024, tom: 16, strony: e202400803), Wydawca: Wiley-VCH GmbH (John Wiley & Sons, Inc.)
    Status:
    Published
    DOI:
    10.1002/cctc.202400803 - link to the publication

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