Projects funded by the NCN

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192 projects found matching your search criteria :

  1. Molecular Mechanisms of Dietary Intervention on Neurodegeneration

    Call: JPND Call 2022 , Panel: NZ2

    Principal investigator: dr hab. Maciej Figiel

    Instytut Chemii Bioorganicznej PAN

  2. tRNA-derived fragments as stress responsive and regulating agents in soybean

    Call: OPUS 24 , Panel: NZ9

    Principal investigator: dr hab. Agata Tyczewska

    Instytut Chemii Bioorganicznej PAN

  3. The genetic basis underlying immune resistance in selected accessions of the model plant A. thaliana against the plant p...

    Call: PRELUDIUM 22 , Panel: NZ2

    Principal investigator: Anastasiia Satyr

    Instytut Chemii Bioorganicznej PAN

  4. Role of hyperhomocysteinemia in scent signalling in mice

    Call: PRELUDIUM 8 , Panel: NZ5

    Principal investigator: Jacek Jakub Wróblewski

    Instytut Chemii Bioorganicznej PAN

  5. In search for DNA methylation aberrations associated with susceptibility to ovarian cancer

    Call: OPUS 26 , Panel: NZ5

    Principal investigator: dr Malwina Magdalena Suszyńska

    Instytut Chemii Bioorganicznej PAN

  6. Proteomic predictors of metastasis in colorectal cancer – a validation study

    Call: OPUS 27 , Panel: NZ5

    Principal investigator: dr hab. Anna Wojakowska

    Instytut Chemii Bioorganicznej PAN

  7. Molecular basis of the function of WRKY transcription factors as pivotal regulators of plant responses to stress

    Call: OPUS 27 , Panel: NZ9

    Principal investigator: dr Marta Grzechowiak

    Instytut Chemii Bioorganicznej PAN

  8. Jump in with a splash: Exploring the principles of long noncoding RNA import into mitochondria and its biological releva...

    Call: OPUS 27 , Panel: NZ3

    Principal investigator: dr hab. Barbara Uszczyńska-Ratajczak

    Instytut Chemii Bioorganicznej PAN

  9. The complex nature of multidomain proteins: the unmasked activity of human Dicer ribonuclease – expect the unexpected

    Call: OPUS 28 , Panel: NZ2

    Principal investigator: dr hab. Anna Maria Kurzyńska-Kokorniak

    Instytut Chemii Bioorganicznej PAN

  10. RNA hairpin structures in biology and pathogenesis. Crystallographic analysis.

    Call: OPUS 1 , Panel: NZ1

    Principal investigator: prof. Wojciech Robert Rypniewski

    Instytut Chemii Bioorganicznej PAN

  11. Copy number polymorphism as a major mechanism influencing variability of plant genomes. Endogenous (RNA interference) an...

    Call: OPUS 1 , Panel: NZ2

    Principal investigator: prof. Marek Marian Figlerowicz

    Instytut Chemii Bioorganicznej PAN

  12. Defining new neurodegeneration mechanisms using the first SCA3/MJD knock-in mouse model.

    Call: SONATA BIS 3 , Panel: NZ4

    Principal investigator: dr hab. Maciej Figiel

    Instytut Chemii Bioorganicznej PAN

  13. Dynasty and population of the Piast State in view of the integrated historical, anthropological and genomic studies

    Call: SYMFONIA 2 , Panel: NZ2

    Principal investigator: prof. Marek Marian Figlerowicz

    Instytut Chemii Bioorganicznej PAN

  14. RNA hybrid duplex-quadruplex structures with dual functionality as a new tool for silecing of gene expression

    Call: OPUS 7 , Panel: ST5

    Principal investigator: prof. Zofia Janina Gdaniec

    Instytut Chemii Bioorganicznej PAN

  15. Long term survival and oxidative stress in hyperhomocysteinemia

    Call: SONATA 9 , Panel: NZ5

    Principal investigator: dr Marta Sikora

    Instytut Chemii Bioorganicznej PAN

  16. Unknown areas of activity of human ribonuclease Dicer

    Call: SONATA BIS 6 , Panel: NZ1

    Principal investigator: dr hab. Anna Kurzyńska-Kokorniak

    Instytut Chemii Bioorganicznej PAN

  17. Function of secondary structure of influenza A virus vRNA in ribonucleoprotein complex during viral life cycle

    Call: SONATINA 1 , Panel: NZ1

    Principal investigator: dr Elżbieta Lenartowicz

    Instytut Chemii Bioorganicznej PAN

  18. Investigation of a new therapeutic strategy to lower mutant protein in SCA3 / MJD

    Call: OPUS 21 , Panel: NZ2

    Principal investigator: prof. Maciej Figiel

    Instytut Chemii Bioorganicznej PAN

  19. Close Encounters of the Third Kind: what happens when ribonuclease Dicer encounters in the cell RNA and DNA adopting G-q...

    Call: OPUS 21 , Panel: NZ2

    Principal investigator: dr hab. Anna Maria Kurzyńska-Kokorniak

    Instytut Chemii Bioorganicznej PAN

  20. Game of Tails: Understanding the role of 3'-end processing of long noncoding RNAs during zebrafish development

    Call: PRELUDIUM 21 , Panel: NZ2

    Principal investigator: dr Monika Kwiatkowska

    Instytut Chemii Bioorganicznej PAN

  21. Crystallographic analysis of RNA-ligand complexes. Towards rational design oflead compounds for development of therapies...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Ludmiła Kiliszek

    Instytut Chemii Bioorganicznej PAN

  22. Description of the key mechanisms of coordination and prioritization of barley's response to simultaneous biotic and abi...

    Call: OPUS 23 , Panel: NZ9

    Principal investigator: dr hab. Anna Barbara Piasecka

    Instytut Chemii Bioorganicznej PAN

  23. Microscopic identification of proteins involved in DNA repair of CAG repeats regions

    Call: PRELUDIUM 21 , Panel: NZ3

    Principal investigator: dr Mateusz Przemysław Nowaczyk

    Instytut Chemii Bioorganicznej PAN

  24. Ultrasensitive profiling of mutations driving tumorigenesis in hereditary syndromes associated with tumor suppressor gen...

    Call: OPUS 25 , Panel: NZ5

    Principal investigator: dr Katarzyna Klonowska

    Instytut Chemii Bioorganicznej PAN

  25. Determining the secondary structure and function of BC200 in human brain tumor.

    Call: PRELUDIUM 1 , Panel: NZ3

    Principal investigator: Patrycja Sosińska

    Instytut Chemii Bioorganicznej PAN

  26. Sequence preferences of ribonucleases involved in human microRNA biogenesis.

    Call: OPUS 2 , Panel: NZ1

    Principal investigator: prof. Włodzimierz Krzyżosiak

    Instytut Chemii Bioorganicznej PAN

  27. "RNA toxicity in pathogenesis of polyglutamine diseases"

    Call: MAESTRO 3 , Panel: NZ1

    Principal investigator: dr hab. Maciej Figiel

    Instytut Chemii Bioorganicznej PAN

  28. Active transport systems as an element that controls the molecular cross-talk between symbionts during arbuscular mycorr...

    Call: SONATA 9 , Panel: NZ3

    Principal investigator: dr Joanna Banasiak

    Instytut Chemii Bioorganicznej PAN

  29. MicroRNA profiling in cellular models of Huntington's disease generated using iPSC technology

    Call: PRELUDIUM 9 , Panel: NZ2

    Principal investigator: dr Emilia Barbara Kozłowska

    Instytut Chemii Bioorganicznej PAN

  30. Molecular mechanisms underlying loss of a defensive metabolic pathway in a phylogenetic clade of plant species closely r...

    Call: OPUS 9 , Panel: NZ1

    Principal investigator: dr hab. Paweł Bednarek

    Instytut Chemii Bioorganicznej PAN

  31. RAN translation at CAG repeats in spinocerebellar ataxia type 3

    Call: SONATA 10 , Panel: NZ5

    Principal investigator: dr Magdalena Jazurek-Ciesiołka

    Instytut Chemii Bioorganicznej PAN

  32. Catalytic RNS's as a tool for human mitochondrial biotechnology

    Call: PRELUDIUM 11 , Panel: NZ1

    Principal investigator: Paweł Mariusz Głodowicz

    Instytut Chemii Bioorganicznej PAN

  33. The role of protein factors that bind to the 5' non-coding region of human p53 mRNA in regulation of p53 expression at t...

    Call: OPUS 11 , Panel: NZ1

    Principal investigator: prof. Jerzy Henryk Ciesiołka

    Instytut Chemii Bioorganicznej PAN

  34. Histone demethylase JMJD3 as an epigenetic regulator in the senescence-associated secretory phenotype and cancer

    Call: SONATA 11 , Panel: NZ3

    Principal investigator: dr Patrick McDevitt Perrigue

    Instytut Chemii Bioorganicznej PAN

  35. Shedding new light on genome's dark matter: identification of novel long non-coding RNAs in zebrafish

    Call: OPUS 16 , Panel: NZ2

    Principal investigator: dr hab. Barbara Uszczyńska-Ratajczak

    Instytut Chemii Bioorganicznej PAN

  36. Mechanisms and developmental roles of transcription termination

    Call: OPUS 16 , Panel: NZ1

    Principal investigator: dr hab. Takashi Miki

    Instytut Chemii Bioorganicznej PAN

  37. Molecular basics of type II transmembrane serine proteases (TTSPs)-mediated activation of influenza viruses

    Call: BEETHOVEN LIFE 1 , Panel: NZ1

    Principal investigator: dr Paweł Zmora

    Instytut Chemii Bioorganicznej PAN

  38. Discovering disorders of brain development in Huntington disease as a consequence of putative total huntingtin deficienc...

    Call: OPUS 16 , Panel: NZ3

    Principal investigator: dr hab. Maciej Figiel

    Instytut Chemii Bioorganicznej PAN

  39. Exploring second generation of nucleotide analogues containing phosphoranesulfen- or phosphoraneselenamides as new struc...

    Call: PRELUDIUM 16 , Panel: ST5

    Principal investigator: dr Justyna Gołębiewska

    Instytut Chemii Bioorganicznej PAN

  40. Deciphering the molecular causes and consequences of circular RNAs elevated expression levels in myotonic dystrophy type...

    Call: OPUS 17 , Panel: NZ5

    Principal investigator: dr hab. Marzena Wojciechowska

    Instytut Chemii Bioorganicznej PAN

  41. Chemical architecture of fluorinated nucleoside dimers containing 1,2,3-triazole linker of potential use in molecular bi...

    Call: SONATA 15 , Panel: NZ7

    Principal investigator: dr Dagmara Baraniak

    Instytut Chemii Bioorganicznej PAN

  42. Interspecies metabolic engineering as a tool to investigate immune functions of plant specialized metabolites.

    Call: OPUS 18 , Panel: NZ1

    Principal investigator: prof. Paweł Bednarek

    Instytut Chemii Bioorganicznej PAN

  43. From third ventricle to pituitary gland: regulatory RNA networks in posttranscriptionalmodulation of gene expression in ...

    Call: OPUS 28 (LAP) , Panel: NZ3

    Principal investigator: dr Monika Piwecka

    Instytut Chemii Bioorganicznej PAN

  44. Dynamic RNA structures including pseudoknots and G-quadruplexes of influenza type A virus RNAs as targets for designing ...

    Call: SHENG 4 , Panel: NZ1

    Principal investigator: prof. Elżbieta Beata Kierzek

    Instytut Chemii Bioorganicznej PAN

  45. The use of genome editing systems in experimental therapy of polyglutamine diseases

    Call: ETIUDA 8 , Panel: NZ2

    Principal investigator: Magdalena Dąbrowska

    Instytut Chemii Bioorganicznej PAN

  46. Foldback triplex-forming oligonucleotides as novel tools for G-quadruplex unfolding and selective inhibition of c-Myc on...

    Call: OPUS 19 , Panel: NZ7

    Principal investigator: prof. Anna Pasternak

    Instytut Chemii Bioorganicznej PAN

  47. Application of small compounds in the epigenetic therapy of malignant brain gliomas

    Call: OPUS 19 , Panel: NZ5

    Principal investigator: prof. Mirosława Zofia Naskręt-Barciszewska

    Instytut Chemii Bioorganicznej PAN

  48. Non-coding RNAs at single-cell resolution in the pituitary gland and their role in the regulation of gene expression

    Call: OPUS 19 , Panel: NZ3

    Principal investigator: dr hab. Monika Piwecka

    Instytut Chemii Bioorganicznej PAN

  49. ABCG driven transport of phenylpropanoids in Medicago truncatula - a versatile but adapted scenario.

    Call: OPUS 20 , Panel: NZ9

    Principal investigator: prof. Michał Jasiński

    Instytut Chemii Bioorganicznej PAN

  50. Long noncoding RNA - new aim of anti-influenza therapy

    Call: SONATA 16 , Panel: NZ6

    Principal investigator: dr Marta Soszyńska-Jóźwiak

    Instytut Chemii Bioorganicznej PAN

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