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Long noncoding RNA - new aim of anti-influenza therapy

2020/39/D/NZ6/03267

Keywords:

influenza virus long noncoding RNA RNA secondary structure viral replication cycle

Descriptors:

  • NZ1_004:
  • NZ6_005:

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Instytut Chemii Bioorganicznej PAN

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Marta Soszyńska-Jóźwiak 

Number of co-investigators in the project: 4

Call: SONATA 16 - announced on 2020-09-15

Amount awarded: 1 535 980 PLN

Project start date (Y-m-d): 2021-09-01

Project end date (Y-m-d): 2026-08-31

Project duration:: 60 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (3)
  1. Structural architecture of the human long non-coding RNA-PAAN as a potential target for anti-influenza drug development
    Authors:
    Izabela Ulanowska, Ryszard Kierzek, Elzbieta Kierzek, Marta Soszynska-Jozwiak
    Academic press:
    JOURNAL OF BIOLOGICAL CHEMISTRY (rok: 2025, tom: 301, strony: 110755), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jbc.2025.110755 - link to the publication
  2. Structural and Functional RNA Motifs of SARS-CoV-2 and Influenza A Virus as a Target of Viral Inhibitors
    Authors:
    Izabela Szczesniak, Agnieszka Baliga-Gil, Aleksandra Jarmolowicz, Marta Soszynska-Jozwiak, Elzbieta Kierzek
    Academic press:
    International Journal of Molecular Sciences (rok: 2023, tom: 24, strony: 2), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms24021232 - link to the publication
  3. Targeting sgRNA N secondary structure as a way of inhibiting SARS-CoV-2 replication
    Authors:
    Baliga-Gil, A., Soszynska-Jozwiak, M., Ruszkowska, A., Szczesniak, I., Kierzek, R., Ciechanowska, M., Trybus, M., Jackowiak, P., Peterson, J.M., Moss, W.N., Kierzek, E.
    Academic press:
    Antiviral Research (rok: 2024, tom: 228, strony: 105946), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.antiviral.2024.105946 - link to the publication

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