Projects funded by the NCN


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58 projects found matching your search criteria :

  1. Phosphorylation-Dependent Regulation of IRS2 by DYRK1A: Implications for Diabetes Therapy

    Call: PRELUDIUM 24 , Panel: NZ1

    Principal investigator: Alicja Bis

    Uniwersytet Jagielloński

  2. Zn2+-dependent competition between CD4 and CD8α coreceprtor for Lck tyrosine kinase

    Call: SONATA 19 , Panel: NZ1

    Principal investigator: dr Anna Marta Kocyła

    Uniwersytet Wrocławski, Wydział Biotechnologii

  3. Deciphering the importance of the intracellular FGFR1 module for cell fate

    Call: OPUS 26 , Panel: NZ1

    Principal investigator: dr hab. Małgorzata Urszula Zakrzewska

    Uniwersytet Wrocławski, Wydział Biotechnologii

  4. Regulacja procesu deoksyhypuzynacji przez kinazy białkowe

    Call: PRELUDIUM 22 , Panel: NZ1

    Principal investigator: Paweł Kochanowski

    Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

  5. Search for novel IKK-β inhibitors in the context of diseases with neuroinflammatory origin – structure-based drug design...

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Emilia Aleksandra Sługocka

    Uniwersytet Jagielloński, Collegium Medicum

  6. The potassium puzzle: unraveling the connection between the potassium channel and lipid kinases in kidney functioning

    Call: OPUS 25 , Panel: NZ1

    Principal investigator: dr hab. Piotr Rajmund Koprowski

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  7. Dissecting the regulatory interplay between proteases and protein kinases in acute lymphoblastic leukemia using mass cyt...

    Call: OPUS 24 , Panel: NZ5

    Principal investigator: dr hab. Marcin Łukasz Poręba

    Politechnika Wrocławska

  8. A double whammy for the NF-κB signalling pathway: development of TAK1 and IKKβ degraders against inflammation-driven dis...

    Call: OPUS 24 (LAP) , Panel: NZ7

    Principal investigator: dr hab. Anna Karolina Więckowska

    Uniwersytet Jagielloński, Collegium Medicum

  9. Thermodynamic contribution of halogen bonds in protein-ligand systems. Design, synthesis, and thermodynamic studies of m...

    Call: PRELUDIUM 21 , Panel: ST4

    Principal investigator: dr Sławomir Jan Kasperowicz

    Instytut Biochemii i Biofizyki PAN

  10. Unraveling mechanisms and physiological outcome of lipid-evoked regulation of proteostasis in the intestine.

    Call: OPUS 23 , Panel: NZ4

    Principal investigator: dr hab. Grzegorz Piotr Sumara

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  11. Novel broad-spectrum central nervous system active substances: optimization of their multi-target profile

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Anna Kaczor

    Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny

  12. Small-molecule inhibitors of protein aggregation and ER stress as a novel strategy against neurodegeneration in the cour...

    Call: PRELUDIUM BIS 3 , Panel: NZ5

    Principal investigator: prof. Ireneusz Jacek Majsterek

    Uniwersytet Medyczny w Łodzi

  13. Research of multifunctional compounds targeting neuroinflammation and cholinergic deficit in Alzheimer's disease

    Call: OPUS 22 (LAP) , Panel: NZ7

    Principal investigator: prof. Kinga Aleksandra Sałat

    Uniwersytet Jagielloński, Collegium Medicum

  14. Cell-based high-throughput screening for small-molecule compounds diminishing molecular markers of pathogenesis in myoto...

    Call: OPUS 20 , Panel: NZ3

    Principal investigator: dr hab. Marzena Wojciechowska

    Instytut Chemii Bioorganicznej PAN

  15. FAST interactions in cell death regulation

    Call: PRELUDIUM 19 , Panel: NZ1

    Principal investigator: Daria Martyna Dawidziak

    Uniwersytet Warszawski, Wydział Chemii

  16. Role of heteromultimerization of MRCK kinases in physiological and pathological processes.

    Call: PRELUDIUM 18 , Panel: NZ3

    Principal investigator: Brygida Karolina Baran

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  17. Restoration of beta-cell function via inhibition of diabetic kinome.

    Call: SONATA BIS 9 , Panel: NZ1

    Principal investigator: dr Anna Czarna

    Uniwersytet Jagielloński

  18. Multitarget approach to break the vicious circle of tau pathology and neuroinflammation in Alzheimer's disease: developm...

    Call: SONATA BIS 9 , Panel: NZ7

    Principal investigator: dr hab. Anna Karolina Więckowska

    Uniwersytet Jagielloński, Collegium Medicum

  19. Evaluation of endoplasmic reticulum stress control by endogenous lipids in the context of its anticancer therapeutic pot...

    Call: OPUS 17 , Panel: NZ5

    Principal investigator: dr Dariusz Maciej Pytel

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  20. DEVELOPMENT OF NEW CLASS PHOTOACTIVATED ANTICANCER-ANTIFUNGAL COMPOUNDS: CONJUGATES OF GOLD NANOPARTICLE-SUPPORTED QUINO...

    Call: OPUS 17 , Panel: NZ7

    Principal investigator: dr hab. Oleh M. Demchuk

    Katolicki Uniwersytet Lubelski Jana Pawła II, Wydział Medyczny

  21. Therapeutic potential of biased 5-HT7 receptor ligands in the treatment of depression

    Call: OPUS 17 , Panel: NZ7

    Principal investigator: prof. Paweł Maria Zajdel

    Uniwersytet Jagielloński, Collegium Medicum

  22. Evaluation of the impact of exercise / stress stimuli on the mechanisms and efficacy of beta-hydroxy-beta-methylbutyric ...

    Call: SONATA 14 , Panel: NZ7

    Principal investigator: dr Krzysztof Durkalec-Michalski

    Uniwersytet Przyrodniczy w Poznaniu, Wydział Nauk o Żywności i Żywieniu

  23. Structure and function of a unique two-component system of periodontopathogenic bacteria Porphyromonas gingivalis

    Call: OPUS 16 , Panel: NZ1

    Principal investigator: prof. Jan Stanisław Potempa

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  24. Role of the lysosomes in insulin-dependent regulation of AMP-ativated protein kinase expression and activity in podocyte...

    Call: PRELUDIUM 15 , Panel: NZ4

    Principal investigator: Patrycja Rachubik

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  25. Integrating light and osmotic stress signaling- molecular functions of Plastid Movement Impaired 1 protein from Arabidop...

    Call: OPUS 15 , Panel: NZ3

    Principal investigator: dr Olga Sztatelman

    Instytut Biochemii i Biofizyki PAN

  26. SnRK2 protein kinases as integrators of environmental signals in the regulation of the senescence in plants

    Call: OPUS 14 , Panel: NZ3

    Principal investigator: dr Anna Marta Kulik

    Instytut Biochemii i Biofizyki PAN

  27. Role of a protein kinase-like effector HopBF1 in virulence of bacterial pathogens.

    Call: OPUS 13 , Panel: NZ1

    Principal investigator: dr hab. Magdalena Krzymowska

    Instytut Biochemii i Biofizyki PAN

  28. Estrogen dependent signal transduction associated with PELP1 protein in male reproductive system

    Call: SONATA 12 , Panel: NZ5

    Principal investigator: dr Izabela Skibińska

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Nauk o Zdrowiu

  29. Protein kinase B signalling pathway in glioblastoma cells transfected with sequence encoding liver-type glutaminase (GAB...

    Call: PRELUDIUM 12 , Panel: NZ5

    Principal investigator: Ewelina Julia Majewska

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  30. The role of SnRK2 kinases in regulation of pre-mRNA alternative splicing and miRNA biogenesis in plants response to sali...

    Call: OPUS 12 , Panel: NZ3

    Principal investigator: dr hab. Grażyna Anna Dobrowolska

    Instytut Biochemii i Biofizyki PAN

  31. ADAM17 as a key protein in cellular response to proinflammatory mediators

    Call: OPUS 11 , Panel: NZ3

    Principal investigator: prof. Joanna Katarzyna Bereta

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  32. SOD1 superoxide dismutase regulation in stomatal closure signalling in A. thaliana.

    Call: SONATA 10 , Panel: NZ3

    Principal investigator: dr Hanna Maria Gałgańska

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  33. Mitochondrial nucleoside diphosphate kinase (NDPK) as a regulator of mitochondrial proton leak catalyzed by purine nucle...

    Call: SONATA 10 , Panel: NZ3

    Principal investigator: dr Andrzej Marek Woyda-Płoszczyca

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  34. Protein and gene expression analysis in the course of renal cancer stem-like cells' primary resistance to sorafenib in h...

    Call: PRELUDIUM 9 , Panel: NZ5

    Principal investigator: Zofia Felicja Bielecka

    Wojskowy Instytut Medyczny

  35. Changes in iron metabolism induced by anticancer compounds in in vitro and in vivo

    Call: OPUS 9 , Panel: NZ7

    Principal investigator: prof. Jędrzej Antosiewicz

    Gdański Uniwersytet Medyczny, Wydział Nauk o Zdrowiu z Instytutem Medycyny Morskiej i Tropikalnej

  36. Structure-function studies of RNA-binding proteins with FAST motifs and a RAP domain.

    Call: SONATA 8 , Panel: NZ1

    Principal investigator: dr Maria Wiktoria Górna

    Uniwersytet Warszawski, Wydział Chemii

  37. The functional meaning of the protein kinase C beta (PKC beta) translocation due to cerebral ischemia. Solving the puzzl...

    Call: SONATA 8 , Panel: NZ3

    Principal investigator: dr Małgorzata Beręsewicz

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  38. Role of protein kinase G type I alpha in the regulation of filtration barrier in glomerular dysfunction.

    Call: SONATA BIS 4 , Panel: NZ4

    Principal investigator: dr hab. Agnieszka Piwkowska

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  39. Enzymatic catalysis as a versatile tool for the synthesis of 1,3-dimethylxanthine derivatives with potential anticancer ...

    Call: PRELUDIUM 7 , Panel: ST5

    Principal investigator: dr Paweł Borowiecki

    Politechnika Warszawska, Politechnika Warszawska

  40. Understanding the mechanism of action for small molecule kinase inhibitors in alleviating myotonic dystrophy type 1 (DM1...

    Call: OPUS 7 , Panel: NZ5

    Principal investigator: dr hab. Marzena Wojciechowska

    Instytut Chemii Bioorganicznej PAN

  41. Regulation of photosynthesis and growth of Arabidopsis thaliana under salt stress.

    Call: SONATA 7 , Panel: NZ3

    Principal investigator: dr Anna Marta Kulik

    Instytut Biochemii i Biofizyki PAN

  42. Hydration effects in protein kinases

    Call: SONATA 6 , Panel: ST4

    Principal investigator: dr Piotr Mikołaj Setny

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  43. Study of function of ZmCPK11 and its closest homologues from Arabidopsis thaliana in abiotic stresses

    Call: OPUS 5 , Panel: NZ3

    Principal investigator: dr Jadwiga Helena Szczegielniak

    Instytut Biochemii i Biofizyki PAN

  44. Investigation of the mechanisms of stress induced changes in synaptic plasticity in the dentate gyrus of mice.

    Call: SONATA 5 , Panel: NZ4

    Principal investigator: dr Jadwiga Spyrka

    Uniwersytet Jagielloński, Wydział Biologii i Nauk o Ziemi

  45. Assembly analysis of MAPKKK18 protein complexes: characterisation of MAPKKK18-dependent ABA signalling pathway

    Call: OPUS 3 , Panel: NZ3

    Principal investigator: dr Agnieszka Ludwików

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  46. Modification of glomerular filtration barrier permeability by the insulin, oxidative stress and protein kinase G type I ...

    Call: OPUS 3 , Panel: NZ4

    Principal investigator: dr hab. Agnieszka Piwkowska

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  47. Contribution of calcium-dependent protein kinases (CDPKs) to signalling pathways of abiotic and biotic stresses in potat...

    Call: OPUS 3 , Panel: NZ3

    Principal investigator: dr Lidia Polkowska-Kowalczyk

    Instytut Biochemii i Biofizyki PAN

  48. Mechanisms underlaying the signaling function of PKC beta I and beta II in mitochondria after cerebral ischemia

    Call: OPUS 3 , Panel: NZ3

    Principal investigator: prof. Barbara Małgorzata Zabłocka

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  49. The role of the FAM69 protein family in the nervous system.Analysis of a novel family with potential protein kinase func...

    Call: OPUS 3 , Panel: NZ3

    Principal investigator: dr hab. Krzysztof Piotr Pawłowski

    Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Wydział Rolnictwa i Biologii

  50. The role of sirtuins and AMPK protein kinase in insulin resistance of podocytes

    Call: OPUS 3 , Panel: NZ5

    Principal investigator: dr Dorota Rogacka

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN