Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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ADAM17 as a key protein in cellular response to proinflammatory mediators

2016/21/B/NZ3/00355

Keywords:

inflammation shedding ADAM17 transcription factors MAP kinases DNA methylation secretome

Descriptors:

  • NZ3_7: Signal transduction

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Joanna Bereta 

Number of co-investigators in the project: 6

Call: OPUS 11 - announced on 2016-03-15

Amount awarded: 813 800 PLN

Project start date (Y-m-d): 2017-02-06

Project end date (Y-m-d): 2021-11-05

Project duration:: 57 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. laptop wyposażony w dysk SSD oraz dwa dyski zewnętrzne.

Information in the final report

  • Publication in academic press/journals (3)
  1. Construction of a set of novel transposon vectors for efficient silencing of protein and lncRNA genes via CRISPR interference
    Authors:
    Maria Czarnek, Jakub Kochan, Mateusz Wawro, Rafał Myrczek, Joanna Bereta
    Academic press:
    Molecular Biotechnology (rok: 2023, tom: brak, strony: brak), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1007/s12033-023-00675-5 - link to the publication
  2. shRNAs targeting mouse Adam10 diminish cell response to proinflammatory stimuli independently of Adam10 silencing
    Authors:
    Maria Czarnek, Krystyna Stalińska, Katarzyna Sarad, Joanna Bereta
    Academic press:
    Biology Open (rok: 2022, tom: 11 (3), strony: bio059092), Wydawca: The Company of Biologists
    Status:
    Published
    DOI:
    10.1242/bio.059092 - link to the publication
  3. Non-targeting control for MISSION shRNA library silences SNRPD3 leading to cell death or permanent growth arrest
    Authors:
    Maria Czarnek, Katarzyna Sarad, Agnieszka Karaś, Jakub Kochan, Joanna Bereta
    Academic press:
    Molecular Therapy - Nucleic Acids (rok: 2021, tom: 26, strony: 711–731), Wydawca: Cell Press
    Status:
    Published
    DOI:
    10.1016/j.omtn.2021.09.004 - link to the publication

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