Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Structure-function studies of RNA-binding proteins with FAST motifs and a RAP domain.

2014/15/D/NZ1/00968

Keywords:

protein X-ray crystallography RNA binding domain FASTK RAP post-transcriptional regulation atypical protein kinase structural biology mitochondrial protein RNA metabolism.

Descriptors:

  • NZ1_4: Structural biology
  • NZ1_2: Biochemistry
  • NZ1_1: Molecular biology

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet Warszawski, Wydział Chemii

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Maria Górna 

Number of co-investigators in the project: 3

Call: SONATA 8 - announced on 2014-09-15

Amount awarded: 1 597 212 PLN

Project start date (Y-m-d): 2015-09-22

Project end date (Y-m-d): 2019-09-21

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Komputery (stacjonarne lub laptopy) wraz z oprogramowaniem i zewnętrzną pamięcią przenośną (3 szt.) (10 192 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  1. The Repeating, Modular Architecture of the HtrA Proteases
    Authors:
    Matthew Merski, Sandra Macedo-Ribeiro, Rafal M Wieczorek, Maria W Górna
    Academic press:
    Biomolecules (rok: 2022, tom: 12(6), strony: 793), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/biom12060793 - link to the publication
  2. Thiamin-Diphosphate Enzymes Are an Ancient Family of Repeat Proteins
    Authors:
    Matthew Merski, Maria Górna
    Academic press:
    bioRxiv , Wydawca: Cold Spring Harbor Laboratory
    Status:
    Submitted
    DOI:
    10.1101/2021.03.21.436335 - link to the publication
  3. Self-analysis of repeat proteins reveals evolutionarily conserved patterns
    Authors:
    Matthew Merski; Krzysztof Młynarczyk; Jan Ludwiczak; Jakub Skrzeczkowski; Stanisław Dunin-Horkawicz; Maria W. Górna
    Academic press:
    BMC Bioinformatics (rok: 2020, tom: 21, strony: 179), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1186/s12859-020-3493-y - link to the publication
  4. The Effect of Mutations in the TPR and Ankyrin Families of Alpha Solenoid Repeat Proteins
    Authors:
    Matylda A Izert, Patrycja E Szybowska, Maria W.Górna, Matthew Merski
    Academic press:
    Frontiers in Bioinformatics (rok: 2021, tom: 1, strony: 696368), Wydawca: Frontiers Media
    Status:
    Published
    DOI:
    10.3389/fbinf.2021.696368 - link to the publication

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