Projects funded by the NCN

Dual-Target Compounds Modulating EAAT2 and Kv7.2/3 Channels: A Rational Strategy Toward Novel Antiseizure and Antinocice...

Call: OPUS 29 , Panel: NZ7

Principal investigator: dr Michał Andrzej Abram

Uniwersytet Jagielloński

Development of novel 1,3-selenazol-2-one derivatives incorporated into self-emulsifying drug delivery systems as a strat...

Call: OPUS 29 , Panel: NZ7

Principal investigator: dr hab. Robert Czarnomysy

Uniwersytet Medyczny w Białymstoku

Disrupting the Toxic NMDAR/TRPM4 Protein Dialogue as a Novel Neuroprotective Strategy: Development of Small-Molecule Inh...

Call: PRELUDIUM 24 , Panel: NZ7

Principal investigator: Katarzyna Aleksandra Szafrańska

Uniwersytet Jagielloński

Synthesis of novel hybrid nanomaterials based on fullerene scaffold for photodynamic therapy of cancer

Call: PRELUDIUM 23 , Panel: NZ7

Principal investigator: Dominik Jakub Dreszer

UNIWERSYTET ŚLĄSKI

Miniature CRISPR/Cas nucleases for upregulation of utrophin expression: a novel approach for mutation-independent therap...

Call: DAINA 3 , Panel: NZ3

Principal investigator: prof. Józef Dulak

Uniwersytet Jagielloński

Cuproptosis, a novel pathway of regulated cell death as a therapeutic target in treatment-naïve and targeted therapy-res...

Call: OPUS 25 , Panel: NZ5

Principal investigator: dr hab. Mariusz Łukasz Hartman

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Targeting Energy Metabolism for Precision Cancer Therapy: Novel Inhibitors of LDH-A and PDK1 as Potential Strategies to ...

Call: PRELUDIUM 22 , Panel: NZ7

Principal investigator: Marika Anna Frańczak

Gdański Uniwersytet Medyczny, Wydział Lekarski

Chimeric Rhodopsin as a novel optogenetic tool

Call: SONATINA 7 , Panel: NZ5

Principal investigator: dr Jagoda Płaczkiewicz

Instytut Chemii Fizycznej Polskiej Akademii Nauk, Międzynarodowe Centrum Badań Oka

Modulation of HIV-1 epitranscriptome: A novel approach to improve "shock & kill" therapy.

Call: PRELUDIUM 21 , Panel: NZ6

Principal investigator: Haider Ali brak danych

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

Mechanisms and consequences of CD19 loss in B-acute lymphoblastic leukaemia patients relapsing after CD19-CAR-T cell the...

Call: PRELUDIUM BIS 3 , Panel: NZ5

Principal investigator: prof. Przemysław Juszczyński

Instytut Hematologii i Transfuzjologii

The interplay of neurochemistry and cancer biology: in the search for novel glioblastoma multiforme therapy among dopami...

Call: SONATA 17 , Panel: NZ7

Principal investigator: dr Katarzyna Maria Kucwaj-Brysz

Uniwersytet Jagielloński, Collegium Medicum

Proline metabolism as a novel therapeutic target for diseases associated with mitochondrial dysfunction.

Call: SONATA BIS 11 , Panel: NZ3

Principal investigator: dr Karolina Szczepanowska

Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

Novel BODIPY derivatives and ruthenium complexes conjugates as photosensitizers for bacterial inactivation in the in viv...

Call: PRELUDIUM 20 , Panel: NZ7

Principal investigator: Weronika Porolnik

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Selective inhibitors of γ-aminobutyric acid (GABA) transporter subtype 3 (GAT3) as a new pharmacological tools and a cha...

Call: OPUS 21 , Panel: NZ7

Principal investigator: dr Dawid Marcin Panek

Uniwersytet Jagielloński, Collegium Medicum

Novel strategies for pharmacological modulation of platelet-derived microparticles - effects on endothelium

Call: PRELUDIUM 19 , Panel: NZ5

Principal investigator: Agnieszka Agata Pełesz

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

DNA polymerase θ as a novel therapeutic target in personalized anticancer therapy

Call: OPUS 19 , Panel: NZ7

Principal investigator: prof. Tomasz Adam Śliwiński

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Foldback triplex-forming oligonucleotides as novel tools for G-quadruplex unfolding and selective inhibition of c-Myc on...

Call: OPUS 19 , Panel: NZ7

Principal investigator: prof. Anna Pasternak

Instytut Chemii Bioorganicznej PAN

Novel therapy for pulmonary hypertension with dual mechanism of action: Myo-inositol trispyrophosphate targeting both pu...

Call: OPUS 18 , Panel: NZ5

Principal investigator: dr hab. Michał Maria Mączewski

CENTRUM MEDYCZNE KSZTAŁCENIA PODYPLOMOWEGO

Glycoconjugated zinc phthalocyanine as a novel photodynamic therapy tool for the treatment of psoriasis

Call: PRELUDIUM BIS 1 , Panel: NZ4

Principal investigator: prof. Piotr Paweł Ziółkowski

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej

Novel insights into hydrogen sulfide-mediated cytoprotection - can H2S prevent the progression of Duchenne muscular dyst...

Call: OPUS 18 , Panel: NZ3

Principal investigator: prof. Agnieszka Łoboda

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Novel bispecific G-quadruplex conjugates as potential anticancer agents

Call: PRELUDIUM 18 , Panel: NZ7

Principal investigator: dr Carolina Sofia Pereira Roxo

Instytut Chemii Bioorganicznej PAN

Novel nanomaterials based on titanium composites conjugated with affibody molecules with potential photothermal conversi...

Call: PRELUDIUM 18 , Panel: ST5

Principal investigator: Maria Cristina Nevarez Martinez

Uniwersytet Gdański, Wydział Chemii

Novel core-shell micro-sized systems for macrophage-targeted drug delivery via phagocytosis

Call: PRELUDIUM 17 , Panel: NZ7

Principal investigator: dr Tomasz Marek Urbaniak

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej

Definition of targetable signaling pathways in chronic lymphocytic leukemia patients with rationale to novel therapy wit...

Call: PRELUDIUM 16 , Panel: NZ5

Principal investigator: Joanna Knap

Uniwersytet Medyczny w Lublinie, II Wydział Lekarski z Oddziałem Anglojęzycznym

Nowel polymeric nanoparticles for pulmonary nucleic acid therapy - synthesis, toxicological analysis and biological/ther...

Call: BEETHOVEN LIFE 1 , Panel: NZ5

Principal investigator: prof. Maria Jolanta Bryszewska

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

STING protein activation combined with anti-vascular agent as a novel strategy for anticancer therapy

Call: OPUS 16 , Panel: NZ5

Principal investigator: dr hab. Ryszard Smolarczyk

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Oddział w Gliwicach

Novel nanomaterials for triple-punch therapy of liver cancer

Call: OPUS 16 , Panel: ST8

Principal investigator: dr Radosław Grzegorz Mrówczyński

Uniwersytet im. Adama Mickiewicza w Poznaniu, Centrum NanoBioMedyczne

Development of the novel experimental gene therapy approach for glaucoma treatment - focusing on the role of RNA-binding...

Call: SONATA 13 , Panel: NZ4

Principal investigator: dr Adrian Smędowski

Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Medycznych w Katowicach

Design and validation of a novel form of therapy in intestinal inflammation and colitis associated colorectal cancer bas...

Call: OPUS 13 , Panel: NZ5

Principal investigator: prof. Jakub Jerzy Fichna

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

The advanced methods of selecting novel AAV capsids and their use in studies of molecular mechanisms of intracellular bl...

Call: OPUS 13 , Panel: NZ1

Principal investigator: dr Leszek Lisowski

Wojskowy Instytut Higieny i Epidemiologii im. gen. Karola Kaczkowskiego

Insights into biological activity and mechanism of action of novel styrylquinazoline derivatives as tyrosine kinase inhi...

Call: PRELUDIUM 12 , Panel: NZ7

Principal investigator: Katarzyna Anna Malarz

UNIWERSYTET ŚLĄSKI, Wydział Matematyki, Fizyki i Chemii

The research on the use of novel analogues of endogenous antimicrobial peptides in therapy of staphylococcal skin infect...

Call: OPUS 12 , Panel: NZ7

Principal investigator: prof. Wojciech Kamysz

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

Novel cationic photosensitizers for antimicrobial photodynamic therapy (aPDT)

Call: PRELUDIUM 12 , Panel: ST5

Principal investigator: Magdalena Barbara Obłoza

Uniwersytet Jagielloński, Wydział Chemii

Novel glycofullerenes for anti-cancer therapies

Call: SONATA 12 , Panel: NZ7

Principal investigator: dr Maciej Michał Serda

UNIWERSYTET ŚLĄSKI, Wydział Nauk Ścisłych i Technicznych

Evaluation of novel, synergistic drug combinations for the treatment of B cell malignancies

Call: OPUS 11 , Panel: NZ7

Principal investigator: dr Małgorzata Firczuk

Warszawski Uniwersytet Medyczny, Wydział Lekarski

New MOF compounds as degradable nanocontainers of tyrosine kinases inhibitors in novel anti-cancer therapy

Call: OPUS 9 , Panel: ST5

Principal investigator: prof. Artur Piotr Terzyk

Uniwersytet Mikołaja Kopernika, Wydział Chemii

Targeting peripheral cannabinoid receptors CB2 as a novel therapy to treat osteoarthritis

Call: OPUS 7 , Panel: NZ7

Principal investigator: dr hab. Katarzyna Maria Starowicz-Bubak

Instytut Farmakologii PAN

Inhibitors of ER stress dependant PERK kinase as a novel approach for Alzheimer's therapy

Call: HARMONIA 5 , Panel: NZ1

Principal investigator: prof. Ireneusz Jacek Majsterek

Uniwersytet Medyczny w Łodzi, Wydział Wojskowo-Lekarski

The role of poly(ADP-ribose) polymerase and sirtuins in molecular mechanism of cell death. Identification of novel targe...

Call: OPUS 5 , Panel: NZ3

Principal investigator: prof. Joanna Benigna Strosznajder

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Combined stem cell-based and gene therapy as a novel strategy to protect photoreceptors - evaluation of renewal mechanis...

Call: OPUS 4 , Panel: NZ5

Principal investigator: prof. Bogusław Bronisław Machaliński

Pomorski Uniwersytet Medyczny w Szczecinie, Wydział Lekarski z Oddziałem Nauczania w Języku Angielskim

Synthesis and physical-chemical properties of novel dendrimeric porphyrazines of potential usage in medicine and bionano...

Call: SONATA BIS 1 , Panel: NZ7

Principal investigator: dr hab. Tomasz Adam Gośliński

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

Novel model for in vitro analyzing breast cancer, colorectal cancer and prostate cancer cells.

Call: OPUS 1 , Panel: NZ4

Principal investigator: prof. Piotr Rieske

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Novel star polymers as nucleic acids delivery agents

Call: OPUS 1 , Panel: ST5

Principal investigator: dr hab. Agnieszka Kowalczuk

Centrum Materiałów Polimerowych i Węglowych PAN

Iron chelators- the novel approach to anticancer therapy

Call: PRELUDIUM 1 , Panel: NZ4

Principal investigator: Maciej Michał Serda

UNIWERSYTET ŚLĄSKI, Wydział Matematyki Fizyki i Chemii