Projects funded by the NCN

Targeting peripheral cannabinoid receptors CB2 as a novel therapy to treat osteoarthritis

Call: OPUS 7 , Panel: NZ7

Principal investigator: dr hab. Katarzyna Starowicz-Bubak

INSTYTUT FARMAKOLOGII PAN

Inhibitors of ER stress dependant PERK kinase as a novel approach for Alzheimer's therapy

Call: HARMONIA 5 , Panel: NZ1

Principal investigator: prof. Ireneusz Majsterek

Uniwersytet Medyczny w Łodzi, Wydział Wojskowo-Lekarski

Novel star polymers as nucleic acids delivery agents

Call: OPUS 1 , Panel: ST5

Principal investigator: dr hab. Agnieszka Kowalczuk

Centrum Materiałów Polimerowych i Węglowych PAN

The role of poly(ADP-ribose) polymerase and sirtuins in molecular mechanism of cell death. Identification of novel targe...

Call: OPUS 5 , Panel: NZ3

Principal investigator: prof. Joanna Strosznajder

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Combined stem cell-based and gene therapy as a novel strategy to protect photoreceptors - evaluation of renewal mechanis...

Call: OPUS 4 , Panel: NZ5

Principal investigator: prof. Bogusław Machaliński

Pomorski Uniwersytet Medyczny w Szczecinie, Wydział Lekarski z Oddziałem Nauczania w Języku Angielskim

Synthesis and physical-chemical properties of novel dendrimeric porphyrazines of potential usage in medicine and bionano...

Call: SONATA BIS 1 , Panel: NZ7

Principal investigator: dr hab. Tomasz Gośliński

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

Targeting Energy Metabolism for Precision Cancer Therapy: Novel Inhibitors of LDH-A and PDK1 as Potential Strategies to ...

Call: PRELUDIUM 22 , Panel: NZ7

Principal investigator: Marika Frańczak

Gdański Uniwersytet Medyczny, Wydział Lekarski

Chimeric Rhodopsin as a novel optogenetic tool

Call: SONATINA 7 , Panel: NZ5

Principal investigator: dr Jagoda Płaczkiewicz

Instytut Chemii Fizycznej Polskiej Akademii Nauk, Międzynarodowe Centrum Badań Oka

Modulation of HIV-1 epitranscriptome: A novel approach to improve "shock & kill" therapy.

Call: PRELUDIUM 21 , Panel: NZ6

Principal investigator: Haider Ali brak danych (PI has only a Name - in accordance with PESEL)

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

Mechanisms and consequences of CD19 loss in B-acute lymphoblastic leukaemia patients relapsing after CD19-CAR-T cell the...

Call: PRELUDIUM BIS 3 , Panel: NZ5

Principal investigator: prof. Przemysław Juszczyński

Instytut Hematologii i Transfuzjologii

Interleukin-18 receptor targeted gene therapy as a novel approach for the treatment of pulmonary hypertension using cont...

Call: POLONEZ BIS 1 , Panel: NZ5

Principal investigator: dr Tara Scott

Gdański Uniwersytet Medyczny, Wydział Lekarski

The interplay of neurochemistry and cancer biology: in the search for novel glioblastoma multiforme therapy among dopami...

Call: SONATA 17 , Panel: NZ7

Principal investigator: dr Katarzyna Kucwaj-Brysz

Uniwersytet Jagielloński, Collegium Medicum

Proline metabolism as a novel therapeutic target for diseases associated with mitochondrial dysfunction.

Call: SONATA BIS 11 , Panel: NZ3

Principal investigator: dr Karolina Szczepanowska

Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

Novel BODIPY derivatives and ruthenium complexes conjugates as photosensitizers for bacterial inactivation in the in viv...

Call: PRELUDIUM 20 , Panel: NZ7

Principal investigator: Weronika Porolnik

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Selective inhibitors of γ-aminobutyric acid (GABA) transporter subtype 3 (GAT3) as a new pharmacological tools and a cha...

Call: OPUS 21 , Panel: NZ7

Principal investigator: dr Dawid Panek

Uniwersytet Jagielloński, Collegium Medicum

Novel strategies for pharmacological modulation of platelet-derived microparticles - effects on endothelium

Call: PRELUDIUM 19 , Panel: NZ5

Principal investigator: Agnieszka Pełesz

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

DNA polymerase θ as a novel therapeutic target in personalized anticancer therapy

Call: OPUS 19 , Panel: NZ7

Principal investigator: prof. Tomasz Śliwiński

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Foldback triplex-forming oligonucleotides as novel tools for G-quadruplex unfolding and selective inhibition of c-Myc on...

Call: OPUS 19 , Panel: NZ7

Principal investigator: dr hab. Anna Pasternak

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Novel therapy for pulmonary hypertension with dual mechanism of action: Myo-inositol trispyrophosphate targeting both pu...

Call: OPUS 18 , Panel: NZ5

Principal investigator: dr hab. Michał Mączewski

Centrum Medyczne Kształcenia Podyplomowego

Glycoconjugated zinc phthalocyanine as a novel photodynamic therapy tool for the treatment of psoriasis

Call: PRELUDIUM BIS 1 , Panel: NZ4

Principal investigator: prof. Piotr Ziółkowski

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu

Novel insights into hydrogen sulfide-mediated cytoprotection - can H2S prevent the progression of Duchenne muscular dyst...

Call: OPUS 18 , Panel: NZ3

Principal investigator: dr hab. Agnieszka Łoboda

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Novel bispecific G-quadruplex conjugates as potential anticancer agents

Call: PRELUDIUM 18 , Panel: NZ7

Principal investigator: Carolina Pereira Roxo

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Novel nanomaterials based on titanium composites conjugated with affibody molecules with potential photothermal conversi...

Call: PRELUDIUM 18 , Panel: ST5

Principal investigator: Maria Nevarez Martinez

Uniwersytet Gdański, Wydział Chemii

Novel core-shell micro-sized systems for macrophage-targeted drug delivery via phagocytosis

Call: PRELUDIUM 17 , Panel: NZ7

Principal investigator: Tomasz Urbaniak

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu

Definition of targetable signaling pathways in chronic lymphocytic leukemia patients with rationale to novel therapy wit...

Call: PRELUDIUM 16 , Panel: NZ5

Principal investigator: Joanna Knap-Stępień

Uniwersytet Medyczny w Lublinie, Wydział Lekarski

STING protein activation combined with anti-vascular agent as a novel strategy for anticancer therapy

Call: OPUS 16 , Panel: NZ5

Principal investigator: dr hab. Ryszard Smolarczyk

Narodowy Instytut Onkologii im. Marii Skłodowskiej-Curie - Państwowy Instytut Badawczy, Oddział w Gliwicach

Novel nanomaterials for triple-punch therapy of liver cancer

Call: OPUS 16 , Panel: ST8

Principal investigator: dr hab. Radosław Mrówczyński

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

Development of the novel experimental gene therapy approach for glaucoma treatment - focusing on the role of RNA-binding...

Call: SONATA 13 , Panel: NZ4

Principal investigator: dr Adrian Smędowski

Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Medycznych w Katowicach

Novel model for in vitro analyzing breast cancer, colorectal cancer and prostate cancer cells.

Call: OPUS 1 , Panel: NZ4

Principal investigator: prof. Piotr Rieske

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Design and validation of a novel form of therapy in intestinal inflammation and colitis associated colorectal cancer bas...

Call: OPUS 13 , Panel: NZ5

Principal investigator: prof. Jakub Fichna

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

The advanced methods of selecting novel AAV capsids and their use in studies of molecular mechanisms of intracellular bl...

Call: OPUS 13 , Panel: NZ1

Principal investigator: dr Leszek Lisowski

Wojskowy Instytut Higieny i Epidemiologii im. gen. Karola Kaczkowskiego

Molecular and pharmacological approaches based on inhibition of glycolysis to overcome de novo- and antiangiogenic thera...

Call: OPUS 13 , Panel: NZ3

Principal investigator: dr hab. Beata Pająk

Wojskowy Instytut Higieny i Epidemiologii im. gen. Karola Kaczkowskiego

Insights into biological activity and mechanism of action of novel styrylquinazoline derivatives as tyrosine kinase inhi...

Call: PRELUDIUM 12 , Panel: NZ7

Principal investigator: Katarzyna Malarz

Uniwersytet Śląski w Katowicach, Wydział Matematyki, Fizyki i Chemii

The research on the use of novel analogues of endogenous antimicrobial peptides in therapy of staphylococcal skin infect...

Call: OPUS 12 , Panel: NZ7

Principal investigator: prof. Wojciech Kamysz

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

Novel cationic photosensitizers for antimicrobial photodynamic therapy (aPDT)

Call: PRELUDIUM 12 , Panel: ST5

Principal investigator: Magdalena Obłoza

Uniwersytet Jagielloński, Wydział Chemii

Iron chelators- the novel approach to anticancer therapy

Call: PRELUDIUM 1 , Panel: NZ4

Principal investigator: Maciej Serda

UNIWERSYTET ŚLĄSKI w Katowicach, Wydział Matematyki Fizyki i Chemii

Novel glycofullerenes for anti-cancer therapies

Call: SONATA 12 , Panel: NZ7

Principal investigator: dr Maciej Serda

Uniwersytet Śląski w Katowicach, Wydział Nauk Ścisłych i Technicznych

Evaluation of novel, synergistic drug combinations for the treatment of B cell malignancies

Call: OPUS 11 , Panel: NZ7

Principal investigator: dr Małgorzata Firczuk

Warszawski Uniwersytet Medyczny, Wydział Lekarski

New MOF compounds as degradable nanocontainers of tyrosine kinases inhibitors in novel anti-cancer therapy

Call: OPUS 9 , Panel: ST5

Principal investigator: prof. Artur Terzyk

Uniwersytet Mikołaja Kopernika, Wydział Chemii