Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Novel glycofullerenes for anti-cancer therapies

2016/23/D/NZ7/00912

Keywords:

fullerenes glicoconjugation photodynamic therapy drug delivery systems

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology
  • ST5_16:
  • ST5_10: Functional materials/nanomaterials, nanoparticles

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Śląski w Katowicach, Wydział Nauk Ścisłych i Technicznych

woj. śląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Maciej Serda 

Number of co-investigators in the project: 4

Call: SONATA 12 - announced on 2016-09-15

Amount awarded: 783 570 PLN

Project start date (Y-m-d): 2017-07-04

Project end date (Y-m-d): 2021-01-03

Project duration:: 42 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. oprogramowanie ChemBioOffice (4 000 PLN)
  2. spektrofotometr wraz z zestawem komputerowym (145 000 PLN)
  3. zestaw komputerowy (3 500 PLN)
  4. oprogramowanie Mestrenova (2 000 PLN)

Information in the final report

  • Publication in academic press/journals (6)
  • Articles in post-conference publications (1)
  1. A water-soluble [60]fullerene-derivative stimulates chlorophyll accumulation and has no toxic effect on Chlamydomonas reinhardtii*
    Authors:
    Jakub Lang, Mariia Melnykova, Michele Catania, Alicja Inglot, Aleksandra Zyss, Katarzyna Mikruta, Daria Firgolska, Agata Wieremiejczuk, Izabela Książek, Maciej Serda, Paweł Nalepa, Bartosz Pluciński, Aleksandra Giza and Paweł Jedynak
    Academic press:
    Acta Biochimica Polonica (rok: 2019, tom: 66, strony: 257–262), Wydawca: Polish Biochemical Society
    Status:
    Published
    DOI:
    10.18388/abp.2019_2835 - link to the publication
  2. Interactions of aWater-Soluble Glycofullerene with Glucose Transporter 1. Analysis of the Cellular Effects on a Pancreatic Tumor Model
    Authors:
    Edyta Barańska, Olga Wiecheć-Cudak, Monika Rak, Aleksandra Bienia , Anna Mrozek-Wilczkiewicz, Martyna Krzykawska-Serda, and Maciej Serda
    Academic press:
    Nanomaterials (rok: 2021, tom: 11 (2), strony: 513), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/nano11020513 - link to the publication
  3. Development of photoactive Sweet-C60 for pancreatic cancer stellate cell therapy
    Authors:
    Maciej Serda, Matthew J. Ware, Jared M. Newton, Sanchit Sachdeva, Martyna Krzykawska-Serda, Lam Nguyen, Justin Law, Andrew O Anderson, Steven A. Curley, Lon J Wilson, Stuart J Corr
    Academic press:
    Nanomedicine (rok: 2018, tom: 13, strony: 2981-2993), Wydawca: Future Medicine
    Status:
    Published
    DOI:
    10.2217/nnm-2018-0239 - link to the publication
  4. Glycofullerenes as non-receptor tyrosine kinase inhibitors-towards better nanotherapeutics for pancreatic cancer treatment
    Authors:
    Maciej Serda, Katarzyna Malarz, Anna Mrozek-Wilczkiewicz, Marcin Wojtyniak, Robert Musioł, Steven A Curley
    Academic press:
    Scientific Reports (rok: 2019, tom: 10, strony: 45302), Wydawca: Nature Publishing Group
    Status:
    Published
    DOI:
    10.1038/s41598-019-57155- - link to the publication
  5. Developing [60]Fullerene Nanomaterials for Better Photodynamic Treatment of Non-Melanoma Skin Cancers
    Authors:
    Maciej Serda, Grzegorz Szewczyk, Olga Krzysztyńska-Kuleta, Julia Korzuch, Mateusz Dulski, Robert Musioł, and Tadeusz Sarna
    Academic press:
    ACS Biomaterials Science & Engineering (rok: 2020, tom: 6, strony: 5930–5940), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acsbiomaterials.0c00932 - link to the publication
  6. A [60]fullerene nanoconjugate with gemcitabine: synthesis, biophysical properties and biological evaluation for treating pancreatic cancer
    Authors:
    Paweł Nalepa, Robert Gawecki, Grzegorz Szewczyk, Katarzyna Balin, Mateusz Dulski, Mieczysław Sajewicz, Anna Mrozek‑Wilczkiewicz, Robert Musioł, Jaroslaw Polanski and Maciej Serda
    Academic press:
    Cancer Nanotechnology (rok: 2020, tom: 11, strony: 2), Wydawca: BMC
    Status:
    Published
    DOI:
    10.1186/s12645-020-00058-4 - link to the publication
  1. Novel water-solube [60]fullerene nanotherapeutic agent for pancreatic cancer treatment
    Authors:
    M. Serda, M. Ware, J. Newton, S. Sachdeva, K. Malarz, R. Musioł, S. Corr, L. Wilson, S. Curley
    Conference:
    25th Biennial Congress of the European Association for Cancer Research (rok: 2018, ), Wydawca: BMJ Journals
    Data:
    konferencja 30 czerwiec- 3 lipiec 2018
    Status:
    Published

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