Development of the novel experimental gene therapy approach for glaucoma treatment - focusing on the role of RNA-binding proteins
2017/26/D/NZ4/00473
Keywords
Descriptors
- NZ4_7: Neurofizjologia
- NZ4_12: Inne zagadnienia pokrewne
Panel
NZ4 – Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology
Host institution
Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Medycznych w Katowicach
Voivodeship: śląskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 3
Call
SONATA 13 – announced on 2017-06-14
- Amount awarded
- 1 121 620 PLN
- Project start date
- 2018-04-12
- Project end date
- 2021-12-11
- Project duration
- 44 months (the same as in the proposal)
- Project status
- Project settled
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Equipment purchased [PL]
- Aparatura do badań elektroretinograficznych "Celeris". Cost: 250 000 PLN
- Mikroskop operacyjny z światłem koaksjalnym. Cost: 40 000 PLN
- Zestaw do elektroforezy i transferu do Western blot. Cost: 15 000 PLN
Information in the final report
Publication in academic press/journals (3)
-
The Role of Endogenous Neuroprotective Mechanisms in the Prevention of Retinal Ganglion Cells Degeneration
- Authors:
- Marita Pietrucha-Dutczak, Marialaura Amadio, Stefano Govoni, Joanna Lewin-Kowalik, Adrian Smedowski
- Academic press:
- Frontiers in Neuroscience (year: 2018, volume: 12, pages: 834), Publisher: Frontiers
- Status:
- Published
- DOI:
- 10.3389/fnins.2018.00834 – link to the publication
-
Electrical synapses interconnecting axons revealed in the optic nerve head - a novel model of gap junctions' involvement in optic nerve function
- Authors:
- Smedowski Adrian, Akhtar Saeed, Liu Xiaonan, Pietrucha-Dutczak Marita, Podracka Lucia, Toropainen Elisa, Alkanaan Alkanaan, Ruponen Marika, Urtti Arto, Varjosalo Markku, Kaarniranta Kai, Lewin-Kowalik Joanna.
- Academic press:
- Acta Ophthalmologica (year: 2019, volume: 10, pages: 46032), Publisher: Wiley
- Status:
- Published
- DOI:
- 10.1111/aos.14272 – link to the publication
-
Deficiency of the RNA-binding protein ELAVL1/HuR leads to the failure of endogenous and exogenous neuroprotection of retinal ganglion cells
- Authors:
- Anna Pacwa, Joanna Machowicz, Saeed Akhtar, Piotr Rodak, Xiaonan Liu, Marita Pietrucha-Dutczak, Joanna Lewin-Kowalik, Marialaura Amadio and Adrian Smedowski
- Status:
- Accepted for publication