Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Novel star polymers as nucleic acids delivery agents

2011/01/B/ST5/05982

Keywords:

star polymers gene therapy polyplexes nanoparticles

Descriptors:

  • ST5_12: Methods of nanomaterials/materials synthesis
  • ST5_21:
  • ST5_11: Smart materials – self assembled materials, external stimuli-responsive materials

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Centrum Materiałów Polimerowych i Węglowych PAN

woj. śląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Agnieszka Kowalczuk 

Number of co-investigators in the project: 7

Call: OPUS 1 - announced on 2011-03-15

Amount awarded: 495 000 PLN

Project start date (Y-m-d): 2011-12-01

Project end date (Y-m-d): 2015-05-31

Project duration:: 42 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Zetasizer (135 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  1. Loading of polymer nanocarriers: Factors, mechanisms and applications
    Authors:
    Agnieszka Kowalczuk, Roza Trzcinska, Barbara Trzebicka, Andrzej Dworak, Axel H. E. Müller, Christo B. Tsvetanov
    Academic press:
    Progress in Polymer Science (rok: 2014, tom: 39, strony: 43-86), Wydawca: Elsevier
    Status:
    Published
  2. Polycationic star polymers with hyperbranched cores for gene delivery
    Authors:
    Barbara Mendrek, Łukasz Sieroń, Marcin Libera, Mario Smet, Barbara Trzebicka, Aleksander L. Sieroń, Andrzej Dworak, Agnieszka Kowalczuk
    Academic press:
    Polymer (rok: 2014, tom: 55, strony: 4551-4562), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.polymer.2014.07.013 - link to the publication
  3. Non-viral plasmid DNA carriers based on N,N'-dimethylaminoethyl methacrylate and di(ethylene glycol) methyl ether methacrylate star copolymers
    Authors:
    Barbara Mendrek, Łukasz Sieroń, Iwona-Żymełka-Miara, Paulina Binkiewicz, Marcin Libera, Mario Smet, Barbara Trzebicka, Aleksander L. Sieroń, Agnieszka Kowalczuk, Andrzej Dworak
    Academic press:
    Biomacromolecules (tom: -, strony: -), Wydawca: American Chemical Society
    Status:
    Submitted