Projects funded by the NCN


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73 projects found matching your search criteria :

  1. The role of neuronostatin controlling hepatocytes and liver functions in mouse model of obesity

    Call: PRELUDIUM 24 , Panel: NZ4

    Principal investigator: Małgorzata Krążek

    Uniwersytet Przyrodniczy w Poznaniu

  2. Molecular Pathogenesis and Precision Antisense Oligonucleotide Therapy for BAG3-Related Myofibrillar Myopathy Type 6 Usi...

    Call: OPUS 29 , Panel: NZ2

    Principal investigator: dr Estera Elmira Rintz

    Uniwersytet Gdański

  3. Therapeutic evaluation of anti-fibrotic agents for thyroid eye disease (TED) in a preclinical mouse model

    Call: PRELUDIUM 24 , Panel: NZ6

    Principal investigator: Paweł Franciszek Tyrna

    CENTRUM MEDYCZNE KSZTAŁCENIA PODYPLOMOWEGO

  4. Positioning the aryl hydrocarbon receptor (AhR) as a new target for pharmacotherapy of sporadic Alzheimer disease: verif...

    Call: OPUS 28 , Panel: NZ7

    Principal investigator: prof. Małgorzata Kajta

    Instytut Farmakologii PAN

  5. Canonical and non-canonical roles of DDK in oncogenesis: a cornerstone for the development of novel, potent anticancer t...

    Call: SONATA BIS 14 , Panel: NZ3

    Principal investigator: dr Jan Marian Suski

    Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

  6. The role of the estrogen receptor GPER1 in ferroptosis disorders in mouse model of mucopolysaccharidosis type I.

    Call: PRELUDIUM 23 , Panel: NZ3

    Principal investigator: Magdalena Żabińska

    Uniwersytet Gdański

  7. Spatial visual transcriptomics approach of male and female gonad - validation of the role of candidate infertility genes...

    Call: OPUS 27 , Panel: NZ5

    Principal investigator: dr hab. Marta Anna Olszewska

    Instytut Genetyki Człowieka PAN

  8. Role of gut metabolites in immunomodulation of Graves' disease and orbitopathy in preclinical mouse model

    Call: OPUS 26 , Panel: NZ6

    Principal investigator: dr hab. Marlena Godlewska

    CENTRUM MEDYCZNE KSZTAŁCENIA PODYPLOMOWEGO

  9. Is metformin having a cardioprotective role in mouse model of autoimmune myocarditis. Evaluation of the mechanism of act...

    Call: SONATA 19 , Panel: NZ7

    Principal investigator: dr Monika Marta Stefańska

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Centrum Zaawansowanych Technologii

  10. Dietary treatment in genetic mouse model of autism.

    Call: OPUS 26 , Panel: NZ4

    Principal investigator: dr Bożena Joanna Kuźniewska

    Uniwersytet Warszawski, Wydział Biologii

  11. The Impact of Undernutrition on Host Microbiome: the Messenger Role of Bacterial Extracellular Vesicles.

    Call: SONATA 19 , Panel: NZ7

    Principal investigator: dr Agnieszka Maria Razim

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  12. Evaluation of P2X7 purinergic receptor as a trigger of brain metabolic abnormalities and neuronal degeneration in a mous...

    Call: SONATA BIS 13 , Panel: NZ4

    Principal investigator: dr Anna Wilkaniec

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  13. Inactivation of intracellular Staphylococcus aureus and staphylococcal enterotoxins with photoactivated compounds in mod...

    Call: OPUS 25 , Panel: NZ7

    Principal investigator: dr hab. Joanna Nakonieczna

    Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

  14. Mechanisms of somatosensory processing deficits in tuberous sclerosis

    Call: SONATINA 7 , Panel: NZ4

    Principal investigator: dr Marcin Andrzej Lipiec

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  15. Sensing sociability: the neural basis of differences in social behavior.

    Call: MAESTRO 14 , Panel: NZ4

    Principal investigator: dr hab. Ewelina Anna Knapska

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  16. Evaluation of butterbur (Petasites spp) for the antimigraine potential: Isolation of bioactive secondary metabolites (pe...

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: Łukasz Dawid Kulinowski

    Uniwersytet Medyczny w Lublinie

  17. The effect of age and diet on dWAT lipid metabolism in mouse model.

    Call: SONATINA 6 , Panel: NZ5

    Principal investigator: dr Katarzyna Anna Walendzik

    Instytut Rozrodu Zwierząt i Badań Żywności PAN

  18. The role of Brain Derived Neurotrophic Factor (BDNF) and electrical synapses in the neuroprotective activity of Escitalo...

    Call: PRELUDIUM BIS 3 , Panel: NZ5

    Principal investigator: dr hab. Adrian Smędowski

    Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Medycznych w Katowicach

  19. The role of neuronostatin in controlling functions of white and brown adipocytes and adipose tissue and metabolism in mo...

    Call: PRELUDIUM BIS 3 , Panel: NZ4

    Principal investigator: dr hab. Marek Skrzypski

    Uniwersytet Przyrodniczy w Poznaniu, Wydział Medycyny Weterynaryjnej i Nauk o Zwierzętach

  20. The effect of mesenchymal and muscle stem /progenitor cells in the MDX dystrophic mouse model on the function and molecu...

    Call: PRELUDIUM 20 , Panel: NZ3

    Principal investigator: dr Magdalena Nowaczyk

    Instytut Genetyki Człowieka PAN

  21. Long-term exposure to high copper: does it affect the production of pancreatic digestive enzymes?

    Call: PRELUDIUM 20 , Panel: NZ4

    Principal investigator: Daria Patrycja Krzysztofik

    Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

  22. Verification of personalized therapeutic strategy based on Integrated Stress Response inhibition for myeloid neoplasms w...

    Call: OPUS 21 , Panel: NZ5

    Principal investigator: dr hab. Katarzyna Piwocka

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  23. Psychedelics as Therapeutic Candidates in Neurodegenerative Disorders Treatment– a Study in Spinocerebellar Ataxia Type ...

    Call: SONATINA 5 , Panel: NZ4

    Principal investigator: dr Urszula Joanna Kozłowska

    Instytut Chemii Bioorganicznej PAN

  24. Single cell multi-omics in defining how specific oncogenic alterations shape the immune microenvironment and responses t...

    Call: OPUS 20 , Panel: NZ4

    Principal investigator: prof. Bożena Kamińska-Kaczmarek

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  25. What does a viral infection smell like? Analysis of volatile organic compounds and the possibility of their detection on...

    Call: SONATA 16 , Panel: NZ6

    Principal investigator: dr Anna Karolina Matczuk

    Uniwersytet Przyrodniczy we Wrocławiu

  26. The study on the molecular mechanisms of cytotoxic activity of new compounds ZOT5-1-Me and ZOT5-1-Et in an experimental ...

    Call: SONATA 16 , Panel: NZ7

    Principal investigator: dr Paulina Anna Tokarz

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  27. Impairment of coronary microcirculation in a mouse model of a heart failure

    Call: SONATA 16 , Panel: NZ7

    Principal investigator: dr Grzegorz Stanisław Kwiatkowski

    Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

  28. Spatial analysis of the effects of L-DOPA on gene expression in the prefrontal cortex in a mouse model of Parkinson's di...

    Call: PRELUDIUM 19 , Panel: NZ4

    Principal investigator: dr Anna Aleksandra Radlicka-Borysewska

    Instytut Farmakologii PAN

  29. Exploring the mechanisms of therapy-facilitated metastasis and CAAX proteins-processing enzymes in liver cancer

    Call: OPUS 19 , Panel: NZ4

    Principal investigator: dr Jarosław Marek Cisowski

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  30. Validation of a new mouse model for autism spectrum disorder research

    Call: OPUS 19 , Panel: NZ4

    Principal investigator: dr hab. Marta Barbara Wiśniewska

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  31. Mechanism of regulation glycosaminoglycan levels by resveratrol in a mouse model of a neuronopathic disease from the muc...

    Call: PRELUDIUM 18 , Panel: NZ2

    Principal investigator: Estera Elmira Rintz

    Uniwersytet Gdański, Wydział Biologii

  32. Evaluation of the activity of MDM2-p53 antagonist RG7388 in mouse cancer models, alone and in combination with anti-PD-1...

    Call: PRELUDIUM 18 , Panel: NZ5

    Principal investigator: Aneta Sylwia Nieznańska

    Uniwersytet Jagielloński, Wydział Chemii

  33. Involvement of astrocytes in the neuroprotective mechanism evoked by enhancement of noradrenergic transmission in trasng...

    Call: PRELUDIUM 18 , Panel: NZ7

    Principal investigator: Justyna Beata Barut

    Instytut Farmakologii PAN

  34. Effect of Embryonic Diapause on mitochondrial mutations inheritance in the mouse model of obesity.

    Call: PRELUDIUM 18 , Panel: NZ3

    Principal investigator: Łukasz Józef Gąsior

    Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

  35. The role of utrophin in cardiomyopathy in Duchenne muscular dystrophy

    Call: PRELUDIUM 17 , Panel: NZ3

    Principal investigator: dr Kalina Andrysiak

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  36. Linking abnormal Ca2+ signaling and the unfolded protein response with Huntington's disease pathology in both YAC128 mou...

    Call: OPUS 17 , Panel: NZ3

    Principal investigator: dr Magdalena Czeredys

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

  37. Research of a new small-molecule 1,2,4-triazine derivative (MM-129) - assessment of anti-neoplastic activity and safety ...

    Call: OPUS 16 , Panel: NZ7

    Principal investigator: prof. Dariusz Alfred Pawlak

    Uniwersytet Medyczny w Białymstoku, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

  38. Evaluation of tumour metabolomic response to imatinib in a study of mouse xenograft models with gastrointestinal stromal...

    Call: PRELUDIUM 15 , Panel: NZ7

    Principal investigator: Szymon Macioszek

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

  39. The impact of gut microbiota from extremely obese humans on the progression of metabolic syndrome in mouse models

    Call: OPUS 15 , Panel: NZ7

    Principal investigator: prof. Jerzy Zygmunt Ostrowski

    CENTRUM MEDYCZNE KSZTAŁCENIA PODYPLOMOWEGO

  40. Ultrastructure of hair cells of the organ of Corti and the effects of minocycline on responses to acustic stimulation in...

    Call: OPUS 14 , Panel: NZ4

    Principal investigator: dr hab. Magdalena Kinga Dziembowska

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  41. The role of RAGE, receptor for advanced glycation end-products, in the progressive spinal motor neuron degeneration in f...

    Call: OPUS 13 , Panel: NZ4

    Principal investigator: prof. Joanna Alicja Wojtkiewicz

    Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Lekarski

  42. Anti-aging properties of 4-N-furfyrylocytosine in age-differentiated eukaryotic cells, budding yeast and mouse model of ...

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: dr hab. Eliza Sylwia Wyszko

    Instytut Chemii Bioorganicznej PAN

  43. Modulation of mutant huntingtin level by genistein in the mouse model of Huntington's disease and its effects on psychom...

    Call: PRELUDIUM 13 , Panel: NZ2

    Principal investigator: Karolina Pierzynowska

    Uniwersytet Gdański, Wydział Biologii

  44. Mesenchymal stem cells as potential immunosuppression in skeletal muscle cell therapy - studies in a mouse model

    Call: PRELUDIUM 12 , Panel: NZ6

    Principal investigator: dr Barbara Anna Świerczek

    Uniwersytet Warszawski, Wydział Biologii

  45. Changes in protein composition and electrophysiological characteristics of glutamatergic synapse in a mouse model of acu...

    Call: PRELUDIUM 10 , Panel: NZ5

    Principal investigator: Mariusz Paweł Popek

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  46. The influence of a new hybryd compound derived from 2-(2,5-dioxopyrrolidin-1-yl) propanamide on hippocampal neuroprotect...

    Call: OPUS 10 , Panel: NZ7

    Principal investigator: dr hab. Marta Andres-Mach

    Instytut Medycyny Wsi im. Witolda Chodźki

  47. The role of kidneys and haem oxygenase 1 (HO-1) in iron metabolism and haem detoxification during neonatal hyperbilirubi...

    Call: PRELUDIUM 10 , Panel: NZ4

    Principal investigator: Aleksandra Janina Bednarz

    Uniwersytet Jagielloński, Wydział Biologii

  48. Blastomere Biopsy and the onset of Metabolic Syndrome: a risk assessment trial in the mouse model

    Call: SONATA 10 , Panel: NZ4

    Principal investigator: dr Federica Zacchini

    Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

  49. Role of synaptic plasticity impairments in the development of asocial phenotype in mouse models of autism

    Call: SONATA BIS 5 , Panel: NZ4

    Principal investigator: dr Ksenia Zuzanna Meyza

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  50. The potential influence of retinoic acid on endothelial function through change in adipocytes phenotype and adipokines p...

    Call: PRELUDIUM 9 , Panel: NZ5

    Principal investigator: dr Małgorzata Barbara Kalisz

    CENTRUM MEDYCZNE KSZTAŁCENIA PODYPLOMOWEGO