Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Impairment of coronary microcirculation in a mouse model of a heart failure

2020/39/D/NZ7/02593

Keywords:

heart failure coronary microcirculation MRI

Descriptors:

  • NZ7_012:
  • NZ5_003:
  • NZ5_005:

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Grzegorz Stanisław Kwiatkowski 

Number of co-investigators in the project: 3

Call: SONATA 16 - announced on 2020-09-15

Amount awarded: 1 462 962 PLN

Project start date (Y-m-d): 2021-07-22

Project end date (Y-m-d): 2024-07-21

Project duration:: 36 months (the same as in the proposal)

Project status: Project completed

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (3)
  1. Preservation of left ventricle peak and mean pulse flow blood velocity despite progressive deterioration of cardiac function in a chronic heart failure murine model
    Authors:
    Urszula Tyrankiewicz, Grzegorz Kwiatkowski, Stefan Chłopicki
    Academic press:
    Journal of Physiology and Pharmacology (rok: 2021, tom: 72, strony: 595-603), Wydawca: JPP Krakow
    Status:
    Published
    DOI:
    10.26402/jpp.2021.4.11 - link to the publication
  2. Early microvascular coronary endothelial dysfunction precedes pembrolizumab-induced cardiotoxicity. Preventive role of high dose of atorvastatin
    Authors:
    Panagiotis Efentakis, Angeliki Choustoulaki, Grzegorz Kwiatkowski, Aimilia Varela, Ioannis V Kostopoulos, George Tsekenis, Ioannis Ntanasis-Stathopoulos, Anastasios Georgoulis, Constantinos E Vorgias, Harikleia Gakiopoulou, Alexandros Briasoulis, Constantinos H Davos, Nikolaos Kostomitsopoulos, Ourania Tsitsilonis, Meletios Athanasios Dimopoulos, Evangelos Terpos, Stefan Chłopicki, Maria Gavriatopoulou, Ioanna Andreadou
    Academic press:
    Basic Research in Cardiology (rok: 2024, tom: 120, strony: 263–286), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1007/s00395-024-01046-0 - link to the publication
  3. Retrospectively gated ultrashort‐echo‐time MRI T1 mapping reveals compromised pulmonary microvascular NO‐dependent function in a murine model of acute lung injury
    Authors:
    Grzegorz Kwiatkowski, Izabela Czyzynska‐Cichon, Birger Tielemans, Lotte Geerkens, Agnieszka Jasztal, Greetje Vande Velde, Stefan Chłopicki
    Academic press:
    NMR in Biomedicine (rok: 2024, tom: 37, strony: e5105), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/nbm.5105 - link to the publication