Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Role of synaptic plasticity impairments in the development of asocial phenotype in mouse models of autism

2015/18/E/NZ4/00600

Keywords:

autism spectrum disorder animal model synaptic plasticity amygdala

Descriptors:

  • NZ4_7: Neurophysiology
  • NZ4_9: Systems neurobiology
  • NZ3_6: Cell neurobiology

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Instytut Biologii Doświadczalnej im. M. Nenckiego Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Ksenia Meyza 

Number of co-investigators in the project: 3

Call: SONATA BIS 5 - announced on 2015-06-15

Amount awarded: 1 050 000 PLN

Project start date (Y-m-d): 2016-09-01

Project end date (Y-m-d): 2022-08-31

Project duration:: 72 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. CED Power1401-3 do rejestracji sygnałów elektrofizjologicznych (31 000 PLN)
  2. Wytrząsarka kołowa (4 500 PLN)
  3. Wirówka (10 000 PLN)
  4. Oprogramowanie CED Signal6.
  5. Aparat stereotaktyczny z wyświetlaczem cyfrowym (50 000 PLN)
  6. Cieplarka - komora do inkubacji skrawków (7 500 PLN)
  7. Obiektyw fluorescencyjny oraz źródło światła do aparatury elektrofizjologicznej (9 000 PLN)
  8. Oprogramowanie CED Spike2 (9 000 PLN)
  9. Wibratom (40 000 PLN)
  10. Zestaw komputerowy (7 000 PLN)

Information in the final report

  • Publication in academic press/journals (5)
  1. Targeted therapy of cognitive deficits in fragile X syndrome.
    Authors:
    Puścian, A., Winiarski, M., Borowska, J., Łęski, S., Górkiewicz, T., Chaturvedi, M., Nowicka, K., Wołyniak, M., Chmielewska, J. J., Nikolaev, T., Meyza, K., Dziembowska, M., Kaczmarek, L., & Knapska, E.
    Academic press:
    Molecular psychiatry (rok: 2022, tom: 27(6), strony: 2766–2776), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s41380-022-01527-5 - link to the publication
  2. The BTBR mouse model of idiopathic autism - Current view on mechanisms.
    Authors:
    Meyza KZ, Blanchard DC
    Academic press:
    Neuroscience &Biobehavioral Reviews (rok: 2017, tom: 76(Pt A), strony: 99-110), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.neubiorev.2016.12.037 - link to the publication
  3. Social deficits in BTBR T+ Itpr3tf/J mice vary with ecological validity of the test.
    Authors:
    Winiarski, M., Kondrakiewicz, L., Kondrakiewicz, K., Jędrzejewska-Szmek, J., Turzyński, K., Knapska, E., Meyza, K.
    Academic press:
    Genes, brain, and behavior (rok: 2022, tom: 21(5), strony: e12814), Wydawca: Wiley Online Library
    Status:
    Published
    DOI:
    10.1111/gbb.12814 - link to the publication
  4. The roots of empathy: Through the lens of rodent models.
    Authors:
    Meyza KZ, Bartal IB, Monfils MH, Panksepp JB, Knapska E
    Academic press:
    Neuroscience & Biobehavioral Reviews (rok: 2017, tom: 76(Pt B), strony: 216-234), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.028 - link to the publication
  5. What can rodents teach us about empathy?
    Authors:
    Meyza K., Knapska E.
    Academic press:
    Current Opinion in Psychology (rok: 2018, tom: Volume 24, strony: 15-20), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.copsyc.2018.03.002 - link to the publication

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