Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Tregitopes as a novel immunoregulators of pregnancy tolerance in mouse abortion-prone model.

2014/15/N/NZ5/03661

Keywords:

tregitopes prenancy tolerance abortion-prone mouse

Descriptors:

  • NZ5_2: Etiology of animal diseases
  • NZ5_8: Animal disease treatment
  • NZ6_3: Animal immunology

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda PAN

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Anna Kędzierska 

Number of co-investigators in the project: 2

Call: PRELUDIUM 8 - announced on 2014-09-15

Amount awarded: 150 000 PLN

Project start date (Y-m-d): 2015-07-13

Project end date (Y-m-d): 2019-07-12

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Laptop (3 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (1)
  1. CD91 Derived Treg Epitope Modulates Regulatory T Lymphocyte Response, Regulates Expression of Costimulatory Molecules on Antigen-Presenting Cells, and Rescues Pregnancy in Mouse Pregnancy Loss Model
    Authors:
    Anna Ewa Kedzierska, Daria Lorek , Anna Slawek, Tomasz Grabowski, Anna Chelmonska-Soyta
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: brak, strony: brak), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22147296 - link to the publication
  2. Expression of Toll‐like receptors and costimulatory molecules in splenic B cells in a normal and abortion‐prone murine pregnancy model
    Authors:
    Lorek D, Kedzierska AE, Slawek A, Chelmonska‐Soyta A
    Academic press:
    Am J Reprod Immunol. (rok: 2019, tom: brak, strony: brak), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1111/aji.13148 - link to the publication
  3. Tregitopes regulate the tolerogenic immune response and decrease the foetal death rate in abortion-prone mouse matings
    Authors:
    Anna Ewa Kedzierska, Daria Lorek, Anna Slawek, Anna Chelmonska-Soyta
    Academic press:
    Scientific Reports (rok: 2020, tom: brak, strony: brak), Wydawca: Nature publishing group
    Status:
    Published
    DOI:
    10.1038/s41598-020-66957-z. - link to the publication
  1. Tregitopes as a novel immunoregulators of pregnancy tolerance in abortion-prone matings
    Authors:
    A.E. Kedzierska , D. Lorek, A. Slawek, A. Chelmonska-Soyta
    Conference:
    14th European Congress of Reproductive Immunology (rok: 2017, ), Wydawca: Journal of Reproductive Immunology
    Data:
    konferencja 28 Wrzesień-2 Październik 2017
    Status:
    Published
    DOI:
    link to the publication

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