Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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In vivo magnetic resonance evaluation of the progression of extra-retinal neurodegeneration in DBA/2J mouse model of spontaneous glaucoma

2012/07/D/NZ4/04199

Keywords:

glaucoma animal models MRI MRS retinal ganglion cells neuroprotection

Descriptors:

  • NZ4_10: Neuroimaging and computational neuroscience
  • NZ5_3: Pathogenesis of human diseases
  • NZ5_5: Diagnostics in human diseases

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Michał Fiedorowicz 

Number of co-investigators in the project: 4

Call: SONATA 4 - announced on 2012-09-15

Amount awarded: 453 261 PLN

Project start date (Y-m-d): 2013-06-14

Project end date (Y-m-d): 2016-12-13

Project duration:: 42 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Aparat do wyciągania mikropipet (Science Products GmbH) (17 500 PLN)
  2. Elastyczna cewka powierzchniowa z przedwzmacniaczem (42 000 PLN)
  3. Tonometr odbiciowy Tonolab przystosowany do badania gryzoni (27 000 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (3)
  1. Anterograde Transport in Axons of the Retinal Ganglion Cells and its Relationship to the Intraocular Pressure during Aging in Mice with Hereditary Pigmentary Glaucoma
    Authors:
    Fiedorowicz M, Orzel J, KossowskiB, Welniak-Kaminska M, Choragiewicz T, Swiatkiewicz M, Rejdak R, Bogorodzki P, Grieb P
    Academic press:
    Current Eye Research (rok: 2018, tom: 43, strony: 539-546), Wydawca: TAYLOR & FRANCIS INC
    Status:
    Published
    DOI:
    10.1080/02713683.2017.1416147 - link to the publication
  2. Volumes of brain structures in captive wild-type and laboratory rats: 7T magnetic resonance in vivo automatic atlas-based study
    Authors:
    Welniak–Kaminska M , Fiedorowicz M, Orzel J, Bogorodzki P, Modlinska K, Stryjek R, Chrzanowska A, Pisula W, Grieb P
    Academic press:
    PLOS ONE , Wydawca: Public Library of Science
    Status:
    Submitted
    DOI:
    brak - link to the publication
  1. Metabolic hallmarks of visual cortex neurodegeneration in DBA/2J mouse model of glaucoma, a proton magnetic resonance spectroscopy study
    Authors:
    Fiedorowicz M, Orzel J, Kossowski B, Welniak-Kaminska M, Bogorodzki P, Grieb P
    Conference:
    ARVO Annual Meeting (rok: 2015, ), Wydawca: Association for Research in Vision and Ophthalmology (ARVO)
    Data:
    konferencja 6,2015
    Status:
    Published
    DOI:
    link to the publication
  2. Eye morphology quantitated by magnetic resonance imaging in C57Bl/6 mice
    Authors:
    Choragiewicz T, Fiedorowicz M, Welniak-Kaminska M, Orzel J, Bogorodzki P, Rejdak R, Grieb P.
    Conference:
    ARVO Annual Meeting (rok: 2015, ), Wydawca: Association for Research in Vision and Ophthalmology (ARVO)
    Data:
    konferencja 6,2015
    Status:
    Published
    DOI:
    link to the publication
  3. The Impact of Domestication on Cerebral Metabolite Profiles. 1H MRS Study in Wild vs. Laboratory Rats
    Authors:
    Welniak-Kaminska M, Fiedorowicz M, Orzel J, Modlinska K, Stryjek R, Bogorodzki P, Grieb P.
    Conference:
    ESMRMB 34th Annual Scientific Meeting (rok: 2017, ), Wydawca: Springer
    Data:
    konferencja 10,2017
    Status:
    Published

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