Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Search results

94 projects found matching your search criteria :

  1. Serum exosomal miRNAs as novel biomarkers in pediatric B-cell precursor acute lymphoblastic leukemia

    Call: PRELUDIUM 24 , Panel: NZ3

    Principal investigator: Dawid Przystupski

    Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej

  2. Targeted Degradation of the MLL Complex in Leukemia: A PROTAC-Based Therapeutic Strategy

    Call: SONATINA 9 , Panel: ST5

    Principal investigator: dr Natalia Anna Skrzypczak

    Fundacja Uniwersytetu im. Adama Mickiewicza

  3. AI-based model for fast and label-free identification of BAALC overexpression in acute myeloid leukemia cells

    Call: PRELUDIUM 23 , Panel: NZ1

    Principal investigator: Paulina Małgorzata Laskowska

    Instytut Hematologii i Transfuzjologii

  4. Uncovering the NK cell-dependent mechanisms of action of daratumumab in T-ALL

    Call: PRELUDIUM 23 , Panel: NZ3

    Principal investigator: Karolina Maria Bełdzińska-Gądek

    Gdański Uniwersytet Medyczny

  5. Genetic background of chromothripsis, its role in clonal evolution and response to therapy in childhood acute lymphoblas...

    Call: OPUS 27 , Panel: NZ5

    Principal investigator: dr hab. Agata Karolina Pastorczak

    Uniwersytet Medyczny w Łodzi

  6. The role of miRNAs (miR30a, miR30b, miR30c) in RARγ expression in acute myeloid leukemia (AML)

    Call: PRELUDIUM 23 , Panel: NZ5

    Principal investigator: Rafał Skopek

    Instytut Genetyki i Hodowli Zwierząt PAN

  7. Clonal and epigenetic pathways in the development of pediatric acute lymphoblastic leukemia.

    Call: PRELUDIUM 23 , Panel: NZ5

    Principal investigator: Jadwiga Maria Filipek-Gorzała

    Uniwersytet Jagielloński

  8. A machine learning usage to predict venetoclax efficacy and toxicity in chronic lymphocytic leukemia.

    Call: PRELUDIUM 23 , Panel: NZ7

    Principal investigator: Dorota Kruk-Kwapisz

    Warszawski Uniwersytet Medyczny

  9. Stealth" asparaginases as improved protein drugs for the treatment of childhood acute lymphoblastic leukemia (ALL)

    Call: OPUS 27 , Panel: NZ1

    Principal investigator: prof. Matthias Bochtler

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

  10. Identification and characterization of omics profiles in patients' serum during anti-CD19 CAR-T cell therapy

    Call: PRELUDIUM 23 , Panel: NZ5

    Principal investigator: Jaromir Bartosz Tomasik

    Warszawski Uniwersytet Medyczny

  11. Exploring kinase hyperactivation as an innovative approach for chemo-immunotherapy for B cell acute lymphoblastic leukem...

    Call: PRELUDIUM BIS 5 , Panel: NZ7

    Principal investigator: dr hab. Małgorzata Firczuk

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  12. Extensive analysis of the immunological profile of pediatric patients with acute lymphoblastic leukemia in order to iden...

    Call: PRELUDIUM 22 , Panel: NZ5

    Principal investigator: Anna Krętowska-Grunwald

    Uniwersytet Medyczny w Białymstoku

  13. The novel role of CD44 protein in the bone marrow microenvironment-mediated metabolic remodeling of chronic myeloid leuk...

    Call: PRELUDIUM 22 , Panel: NZ3

    Principal investigator: Laura Anna Turos-Korgul

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  14. Differences in the glycoproteomic profile of acute myeloid leukemia (AML) between cytogenetic and risk groups according ...

    Call: PRELUDIUM 22 , Panel: NZ5

    Principal investigator: Tomasz Pieńkowski

    Uniwersytet Medyczny w Białymstoku

  15. Heterogeneity immunocompetent cells during chimeric antigen receptor T cell (CAR-T) CD19 immunotherapy.

    Call: PRELUDIUM 22 , Panel: NZ6

    Principal investigator: Aleksandra Maria Oszer

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  16. Investigating the mechanisms of CD20 downregulation triggered by tyrosine kinase inhibitors in Philadelphia chromosome-p...

    Call: PRELUDIUM 22 , Panel: NZ5

    Principal investigator: Krzysztof Domka

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  17. Dissecting the regulatory interplay between proteases and protein kinases in acute lymphoblastic leukemia using mass cyt...

    Call: OPUS 24 , Panel: NZ5

    Principal investigator: dr hab. Marcin Łukasz Poręba

    Politechnika Wrocławska

  18. Investigating the role of fibroblast growth factor receptors and STAT transcription factors in the targeted therapy of a...

    Call: PRELUDIUM BIS 4 , Panel: NZ5

    Principal investigator: prof. Ewa Teresa Marcinkowska

    Uniwersytet Wrocławski, Wydział Biotechnologii

  19. Unraveling genes and mechanisms underlying relapse of T-cell acute lymphoblastic leukemia

    Call: OPUS 24 , Panel: NZ5

    Principal investigator: dr hab. Małgorzata Agnieszka Dawidowska

    Instytut Genetyki Człowieka PAN

  20. Targeting of metabolic and transcriptomic cross-talk between leukemic cells and macrophages as a therapeutic strategy in...

    Call: OPUS 22 , Panel: NZ5

    Principal investigator: dr Baran Natalia

    Instytut Hematologii i Transfuzjologii

  21. The role of NPM1 as biomarker of the targeted therapy efficacy in chronic lymphocytic leukemia patients

    Call: PRELUDIUM BIS 3 , Panel: NZ5

    Principal investigator: prof. Krzysztof Georgios Giannopoulos

    Uniwersytet Medyczny w Lublinie, Wydział Lekarski

  22. Inhibiting the Mitochondrial Intermembrane Space Assembly pathway as a newapproach to prevent metabolic reprogramming of...

    Call: OPUS 22 , Panel: NZ5

    Principal investigator: dr hab. Carlo Vascotto

    Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

  23. Assessment of SARS-CoV-2 infection in patients with chronic lymphocytic leukemia depending on indicators of immune disor...

    Call: OPUS 21 , Panel: NZ6

    Principal investigator: prof. Ewelina Pia Grywalska

    Uniwersytet Medyczny w Lublinie

  24. Verification of personalized therapeutic strategy based on Integrated Stress Response inhibition for myeloid neoplasms w...

    Call: OPUS 21 , Panel: NZ5

    Principal investigator: dr hab. Katarzyna Piwocka

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  25. Identification of mTOR pathway deregulation mechanisms alternative to mutations in T-cell acute lymphoblastic leukemia (...

    Call: PRELUDIUM 20 , Panel: NZ2

    Principal investigator: Natalia Maćkowska-Maślak

    Instytut Genetyki Człowieka PAN

  26. The role of 5-hydroxymethyluracil in chronic lymphocytic leukemia development

    Call: PRELUDIUM BIS 2 , Panel: NZ5

    Principal investigator: dr hab. Daniel Stefan Gackowski

    Uniwersytet Mikołaja Kopernika, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy, Wydział Farmaceutyczny

  27. Novel L-asparaginases as potential therapeutic agents and antimicrobial targets: structural and functional studies of en...

    Call: OPUS 19 , Panel: NZ1

    Principal investigator: prof. Mariusz Jaskólski

    Instytut Chemii Bioorganicznej PAN

  28. Interactions between γδ T lymphocytes and M-MDSC cells in the pathogenesis of chronic lymphocytic leukemia

    Call: PRELUDIUM 18 , Panel: NZ6

    Principal investigator: Michał Konrad Zarobkiewicz

    Uniwersytet Medyczny w Lublinie, Wydział Lekarski

  29. Improving therapeutic efficacy of anti-CD20 antibodies in precursor B-cell acute lymphoblastic leukemia

    Call: OPUS 18 , Panel: NZ5

    Principal investigator: dr Małgorzata Firczuk

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  30. Identifying the hematopoietic and leukemic stem cell niches

    Call: MOZART , Panel: NZ3

    Principal investigator: dr Krzysztof Szade

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  31. Cell adhesion molecules as regulators of tunneling nanotubes (TNTs) formation and protein transfer in leukemia microenvi...

    Call: PRELUDIUM BIS 1 , Panel: NZ3

    Principal investigator: dr hab. Katarzyna Piwocka

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  32. Investigation of the role of tetraspanins CD20 and CD37 in the biology of neoplastic B cells

    Call: SONATA 15 , Panel: NZ5

    Principal investigator: dr Małgorzata Bobrowicz

    Warszawski Uniwersytet Medyczny, Wydział Lekarski

  33. Epigenetic effect on therapeutic activities of all-trans-retinoic acid in acute myeloid leukemia

    Call: OPUS 17 , Panel: NZ5

    Principal investigator: prof. Arthur Zygmunt Zelent

    Instytut Genetyki i Hodowli Zwierząt PAN

  34. Immunological and molecular characteisitics of chronic myeloid leukemia patients after stopping imatinib

    Call: OPUS 16 , Panel: NZ6

    Principal investigator: prof. Krzysztof Giannopoulos

    Uniwersytet Medyczny w Lublinie, Wydział Lekarski

  35. Definition of targetable signaling pathways in chronic lymphocytic leukemia patients with rationale to novel therapy wit...

    Call: PRELUDIUM 16 , Panel: NZ5

    Principal investigator: Joanna Knap

    Uniwersytet Medyczny w Lublinie, II Wydział Lekarski z Oddziałem Anglojęzycznym

  36. Identifying and overcoming mechanisms promoting resistance to venetoclax in B cell acute lymphoblastic leukemia with MLL...

    Call: PRELUDIUM 16 , Panel: NZ5

    Principal investigator: dr Klaudyna Paulina Fidyt

    Warszawski Uniwersytet Medyczny, Wydział Lekarski

  37. Deciphering molecular mechanism of CDK8 kinase inhibitors action in acute myeloid leukemia

    Call: SONATA BIS 8 , Panel: NZ2

    Principal investigator: dr hab. Michał Marek Mikula

    Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

  38. Tracing the roots of leukemia - how preleukemic hematopoietic stem cells contribute to acute lymphoid and myeloid leukem...

    Call: HARMONIA 10 , Panel: NZ5

    Principal investigator: dr Krzysztof Tomasz Szade

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  39. Role of RNA binding proteins in resistance to therapy of leukemia cells in bone marrow niche

    Call: HARMONIA 10 , Panel: NZ3

    Principal investigator: dr Paulina Podszywałow-Bartnicka

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  40. The role of microbiota-triggered antigen stimulation in development and progression of chronic lymphocytic leukemia

    Call: OPUS 15 , Panel: NZ5

    Principal investigator: prof. Krzysztof Giannopoulos

    Uniwersytet Medyczny w Lublinie, II Wydział Lekarski z Oddziałem Anglojęzycznym

  41. Determining the role of basigin in multiple myeloma and acute myeloid leukaemia development

    Call: PRELUDIUM 15 , Panel: NZ5

    Principal investigator: Piotr Stanisław Łacina

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  42. The role of T regulatory lymphocytes and indoleamine 2,3-dioxygenase in shaping immunosuppressive microenvironment and i...

    Call: OPUS 15 , Panel: NZ6

    Principal investigator: dr Angelika Muchowicz

    Warszawski Uniwersytet Medyczny, Wydział Lekarski

  43. 5-Hydroxylmethyluracil as a potential specific biomarker of leukemic cells in chronic lymphocytic leukemia

    Call: PRELUDIUM 15 , Panel: NZ5

    Principal investigator: Anna Łabejszo

    Uniwersytet Mikołaja Kopernika w Toruniu, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy

  44. BCR-ABL-containing leukemic extracellular vesicles as a novel, immunosuppressive factor controlling function of regulato...

    Call: PRELUDIUM 15 , Panel: NZ3

    Principal investigator: Julian Marek Swatler

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  45. Tunneling nanotubes (TNTs) within the leukemia microenvironment; influence of metabolic remodeling and implications for ...

    Call: OPUS 15 , Panel: NZ3

    Principal investigator: dr hab. Katarzyna Piwocka

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  46. A search for mechanism of anticancer properities of vitamin C; possible link between epigenetic DNA modyfications and vi...

    Call: OPUS 14 , Panel: NZ7

    Principal investigator: prof. Ryszard Oliński

    Uniwersytet Mikołaja Kopernika w Toruniu, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy; Wydział Farmaceutyczny

  47. Identification of novel oncogenic/tumor suppressive miRNA-mRNA interactions in pathogenesis of pediatric T-cell acute ly...

    Call: PRELUDIUM 13 , Panel: NZ2

    Principal investigator: Monika Drobna-Śledzińska

    Instytut Genetyki Człowieka PAN

  48. Crosstalk between fibroblast growth factor receptors signaling and regulation of vitamin D receptor in leukemogenesis.

    Call: OPUS 12 , Panel: NZ5

    Principal investigator: prof. Ewa Teresa Marcinkowska

    Uniwersytet Wrocławski, Wydział Biotechnologii

  49. Role of FMRP protein in the regulation of BRCA1 translation in leukemia cells.

    Call: PRELUDIUM 12 , Panel: NZ3

    Principal investigator: Magdalena Wołczyk

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  50. Influence of bacterial and viral co-infections in the heterogeneic course of chronic lymphocytic leukemia - the role of ...

    Call: OPUS 11 , Panel: NZ6

    Principal investigator: prof. Jacek Mariusz Roliński

    Uniwersytet Medyczny w Lublinie, Wydział Lekarski