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Assessment of SARS-CoV-2 infection in patients with chronic lymphocytic leukemia depending on indicators of immune disorders, with particular emphasis on the role of interferons as natural compounds with therapeutic potential

2021/41/B/NZ6/01765

Keywords

Descriptors

  • NZ6_001: Odporność swoista i nieswoista
  • NZ6_002: Immunologia kliniczna

Panel

NZ6 – Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution

Uniwersytet Medyczny w Lublinie

Voivodeship: lubelskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

prof. Ewelina Pia Grywalska

Number of co-investigators in the project: 7

Call

OPUS 21 – announced on 2021-03-15

Amount awarded
1 999 647 PLN
Project start date
2022-02-01
Project end date
2027-01-31
Project duration
60 months (the same as in the proposal)
Project status
Pending project

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (7)

  1. Immunomodulatory Role of Interferons in Viral and Bacterial Infections

    Authors:
    Paulina Mertowska, Konrad Smolak, Sebastian Mertowski, Ewelina Grywalska
    Academic press:
    International Journal of Molecular Sciences (year: 2023, volume: 24, pages: 46053), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms241210115 – link to the publication

  2. Unraveling the Role of Toll-like Receptors in the Immunopathogenesis of Selected Primary and Secondary Immunodeficiencies

    Authors:
    Paulina Mertowska, Konrad Smolak, Sebastian Mertowski, Ewelina Grywalska
    Academic press:
    Cells (year: 2023, volume: 12, pages: 46049), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/cells12162055 – link to the publication

  3. Programmed Cell Death-1/Programmed Cell Death-1 Ligand as Prognostic Markers of Coronavirus Disease 2019 Severity

    Authors:
    Paulina Niedźwiedzka-Rystwej, Adam Majchrzak, Bogusz Aksak-Wąs, Karol Serwin, Zenon Czajkowski, Ewelina Grywalska, Izabela Korona-Głowniak, Jacek Roliński, Miłosz Parczewski
    Academic press:
    Cells (year: 2022, volume: 11, pages: 46037), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/cells11121978 – link to the publication

  4. SARS-CoV-2 Seroprevalence in HealthcareWorkers before the Vaccination in Poland: Evolution from the First to the Second Pandemic Outbreak

    Authors:
    Izabela Korona-Głowniak, Michał Mielnik, Martyna Podgajna, Ewelina Grywalska, Marek Hus, Katarzyna Matuska, Beata Wojtysiak-Duma, Dariusz Duma, Andrzej Glowniak, Anna Malm
    Academic press:
    International Journal of Environmental Research and Public Health (year: 2022, volume: 19, pages: 46035), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/ijerph19042319 – link to the publication

  5. Could Immune Checkpoint Disorders and EBV Reactivation Be Connected in the Development of Hematological Malignancies in Immunodeficient Patients?

    Authors:
    Paulina Mertowska, Sebastian Mertowski, Konrad Smolak, Gabriela Kita, Katarzyna Guz, Aleksandra Kita, Marcin Pasiarski, Jolanta Smok-Kalwat, Stanisław Góźdź, Ewelina Grywalska
    Academic press:
    Cancers (year: 2023, volume: 15, pages: 46053), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers15194786 – link to the publication

  6. Epstein-Barr virus and immune chaos: the link between reactivation and toll-like receptor dysregulation in immunodeficiency.

    Authors:
    PAULINA MERTOWSKA, SEBASTIAN MERTOWSKI, AUT. ALEKSANDRA KOZIŃSKA, MAŁGORZATA SOBSTYL, JACEK ROLIŃSKI, EWELINA GRYWALSKA.
    Academic press:
    Polish Archives of Internal Medicine (year: 2025, volume: vol. 135 nr 5, pages: 1-12,), Publisher: Polskie Archiwum Medycyny Wewnętrznej
    Status:
    Published
    DOI:
    10.20452/pamw.16973 – link to the publication

  7. Immune Checkpoint Pathway Expression in Lymphocyte Subpopulations in Patients with Common Variable Immunodeficiency and Chronic Lymphocytic Leukemia

    Authors:
    Paulina Mertowska, Sebastian Mertowski, Konrad Smolak, Aleksandra Kita, Gabriela Kita, Katarzyna Guz, Marcin Pasiarski, Ewelina Grywalska
    Academic press:
    Cancers (year: 2023, volume: 15, pages: 17), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers15215184 – link to the publication

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