Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Cell adhesion molecules as regulators of tunneling nanotubes (TNTs) formation and protein transfer in leukemia microenvironment; role in therapy resistance

2019/35/O/NZ3/01936

Keywords:

cancer biology leukemia microenvironment direct cell-cell interactions tunneling nanotubes (TNTs) membrane vesicles adhesion signaling therapy resistance

Descriptors:

  • NZ3_001:
  • NZ3_007:
  • NZ3_003:

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Katarzyna Piwocka 

Number of co-investigators in the project: 2

Call: PRELUDIUM BIS 1 - announced on 2019-09-16

Amount awarded: 532 800 PLN

Project start date (Y-m-d): 2020-10-01

Project end date (Y-m-d): 2025-09-30

Project duration:: 60 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (5)
  1. High-throughput formulation of reproducible 3D cancer microenvironments for drug testing in myeloid leukemia
    Authors:
    M Rudzinska-Radecka#, L Turos-Korgul#, D Mukherjee, P Podszywalow-Bartnicka, K Piwocka* and J Guzowski* (#equal contribution; *correspondence)
    Academic press:
    Biofabrication (rok: 2024, tom: 17(1), strony: 45674), Wydawca: International Society for Biofabrication
    Status:
    Published
    DOI:
    10.1088/1758-5090/ad998d - link to the publication
  2. Stroma-driven horizontal transfer of TCA proteins mediates metabolic plasticity and imatinib resistance in leukemia
    Authors:
    Piotr Chroscicki, Nikodem Kasak, Dorota Dymkowska, Laura Turos-Korgul, Dominik Cysewski, Vira Chumak, Dawid Stepnik, Monika Kusio-Kobialka, Magdalena Lebiedzinska-Arciszewka, Alicja Krop, Mariusz Wieckowski, Tomasz Stoklosa, Krzysztof Zablocki, Agata Kominek, Katarzyna Piwocka
    Academic press:
    Research Square (preprint) (rok: 2025, tom: n/a, strony: 45674), Wydawca: Research Square Preprints
    Status:
    Published
    DOI:
    10.21203/rs.3.rs-6120387/v1 - link to the publication
  3. Tunneling Nanotubes Facilitate Intercellular Protein Transfer and Cell Networks Function
    Authors:
    Laura Turos-Korgul, Marta Dorota Kolba, Piotr Chroscicki, Aleksandra Zieminska, Katarzyna Piwocka
    Academic press:
    Front Cell Dev Biol . (rok: 2022, tom: 10, strony: 915117), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fcell.2022.915117. - link to the publication
  4. Stroma-driven horizontal transfer of TCA proteins mediates metabolic plasticity and imatinib resistance in leukemia
    Authors:
    Piotr Chroscicki, Nikodem Kasak, Dorota Dymkowska, Laura Turos-Korgul, Dominik Cysewski, Vira Chumak, Dawid Stepnik, Monika Kusio-Kobialka, Magdalena Lebiedzinska-Arciszewka, Alicja Krop, Mariusz Wieckowski, Tomasz Stoklosa, Krzysztof Zablocki, Agata Kominek, Katarzyna Piwocka
    Academic press:
    Research Square (preprint) (rok: 2025, tom: n/a, strony: 45674), Wydawca: Research Square Preprints
    Status:
    Published
    DOI:
    10.21203/rs.3.rs-6120387/v1 - link to the publication
  5. High-throughput formulation of reproducible 3D cancer microenvironments for drug testing in myeloid leukemia
    Authors:
    M Rudzinska-Radecka#, L Turos-Korgul#, D Mukherjee, P Podszywalow-Bartnicka, K Piwocka* and J Guzowski* (#equal contribution; *correspondence)
    Academic press:
    Biofabrication (rok: 2024, tom: 17(1), strony: 45674), Wydawca: International Society for Biofabrication
    Status:
    Published
    DOI:
    10.1088/1758-5090/ad998d - link to the publication

O Narodowym Centrum Nauki

Finansowanie nauki

Współpraca zagraniczna

Centrum prasowe

Deklaracja dostępności
Przetwarzanie danych osobowych
Polityka cookies

Partnerzy