Cell adhesion molecules as regulators of tunneling nanotubes (TNTs) formation and protein transfer in leukemia microenvironment; role in therapy resistance

2019/35/O/NZ3/01936

Keywords

Descriptors

  • NZ3_001: Biologia komórki
  • NZ3_007: Przekaźnictwo sygnału
  • NZ3_003: Apoptoza

Panel

NZ3 – Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr hab. Katarzyna Piwocka

Number of co-investigators in the project: 2

Call

PRELUDIUM BIS 1 – announced on 2019-09-16

Amount awarded
532 800 PLN
Project start date
2020-10-01
Project end date
2025-09-30
Project duration
60 months (the same as in the proposal)
Project status
Project completed

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (3)

  1. High-throughput formulation of reproducible 3D cancer microenvironments for drug testing in myeloid leukemia

    Authors:
    M Rudzinska-Radecka#, L Turos-Korgul#, D Mukherjee, P Podszywalow-Bartnicka, K Piwocka* and J Guzowski* (#equal contribution; *correspondence)
    Academic press:
    Biofabrication (year: 2024, volume: 17(1), pages: 46039), Publisher: International Society for Biofabrication
    Status:
    Published
    DOI:
    10.1088/1758-5090/ad998d – link to the publication
  2. Stroma-driven horizontal transfer of TCA proteins mediates metabolic plasticity and imatinib resistance in leukemia

    Authors:
    Piotr Chroscicki, Nikodem Kasak, Dorota Dymkowska, Laura Turos-Korgul, Dominik Cysewski, Vira Chumak, Dawid Stepnik, Monika Kusio-Kobialka, Magdalena Lebiedzinska-Arciszewka, Alicja Krop, Mariusz Wieckowski, Tomasz Stoklosa, Krzysztof Zablocki, Agata Kominek, Katarzyna Piwocka
    Academic press:
    Research Square (preprint) (year: 2025, volume: n/a, pages: 46039), Publisher: Research Square Preprints
    Status:
    Published
    DOI:
    10.21203/rs.3.rs-6120387/v1 – link to the publication
  3. Tunneling Nanotubes Facilitate Intercellular Protein Transfer and Cell Networks Function

    Authors:
    Laura Turos-Korgul, Marta Dorota Kolba, Piotr Chroscicki, Aleksandra Zieminska, Katarzyna Piwocka
    Academic press:
    Front Cell Dev Biol . (year: 2022, volume: 10, pages: 915117), Publisher: Frontiers
    Status:
    Published
    DOI:
    10.3389/fcell.2022.915117. – link to the publication

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