Projects funded by the NCN


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234 projects found matching your search criteria :

  1. The role of DNA methylation in therapy that increases CFTR channel activity in cystic fibrosis

    Call: SONATA 20 , Panel: NZ5

    Principal investigator: dr Beata Maria Narożna

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  2. Mind the gap! Plasmonic nanocavity for spectroscopic trapping of local molecularrearrangements in DNA upon epigenetic mo...

    Call: OPUS 28 , Panel: ST4

    Principal investigator: prof. Ewelina Wioletta Lipiec

    Uniwersytet Jagielloński

  3. The role of EZH2 activity in the development of resistance to targeted therapy in melanoma

    Call: OPUS 28 , Panel: NZ7

    Principal investigator: dr Michał Jerzy Woźniak

    Uniwersytet Medyczny w Łodzi

  4. The role of oral vitamin C supplementation in the epigenetic regulation of male fertility - finding the missing puzzles

    Call: OPUS 28 , Panel: NZ7

    Principal investigator: dr hab. Monika Frączek

    Instytut Genetyki Człowieka Polskiej Akademii Nauk

  5. Revealing the component of epigenetic ageing in monocarpic plant leaves

    Call: SONATA 20 , Panel: NZ9

    Principal investigator: dr Magda Dominika Grabsztunowicz

    Uniwersytet im. Adama Mickiewicza w Poznaniu

  6. The H3K27M oncohistone-centred molecular mechanisms as therapeutic targets in pediatric malignant diffuse midline glioma...

    Call: SONATA BIS 14 , Panel: NZ3

    Principal investigator: dr Katarzyna Leszczyńska

    Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

  7. M6A RNA methylation signatures as a targets for HPV-dependent HNSCC therapy

    Call: OPUS 27 , Panel: NZ5

    Principal investigator: Kamila Ostrowska

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  8. N6-methyladenine metabolism - potential relationships with the development of hematological malignancies.

    Call: OPUS 27 , Panel: NZ5

    Principal investigator: dr Marta Starczak

    Uniwersytet Mikołaja Kopernika w Toruniu

  9. Clonal and epigenetic pathways in the development of pediatric acute lymphoblastic leukemia.

    Call: PRELUDIUM 23 , Panel: NZ5

    Principal investigator: Jadwiga Maria Filipek-Gorzała

    Uniwersytet Jagielloński

  10. From methylation to malformation: the role of DNA methylation in the pathogenesis of Klippel-Feil syndrome

    Call: PRELUDIUM 23 , Panel: NZ5

    Principal investigator: Anna Szoszkiewicz

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  11. Using DNA methylation markers and epigenetic clocks as an innovative tool to assess health, risk indicators, and manage ...

    Call: OPUS 27 , Panel: NZ7

    Principal investigator: dr hab. Ewelina Maria Pośpiech

    Pomorski Uniwersytet Medyczny w Szczecinie

  12. Using genetic and epigenetic data to predict human facial features – developing a theoretical basis for face prediction....

    Call: OPUS 27 , Panel: NZ8

    Principal investigator: prof. Wojciech Branicki

    Uniwersytet Jagielloński

  13. Impact of vitamin D on the epigenetic programming of CD34+ hematopoietic progenitor cells derived from human cord blood

    Call: OPUS 27 , Panel: NZ2

    Principal investigator: prof. Carsten Johannes Carlberg

    Instytut Rozrodu Zwierząt i Badań Żywności Polskiej Akademii Nauk

  14. Searching for novel genetic and epigenetic factors predisposing to osteoarthritis

    Call: OPUS 2 , Panel: NZ2

    Principal investigator: dr hab. Malwina Czarny-Ratajczak

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski I

  15. Semaglutide and neurodevelopment: investigating risks arising from prenatal exposure to a widely popular drug for diabet...

    Call: OPUS 26 , Panel: NZ7

    Principal investigator: dr Agnieszka Wnuk

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  16. Defining the transcriptional and epigenetic state of tumor cells with increased plasticity and the epithelial-endothelia...

    Call: OPUS 26 , Panel: NZ5

    Principal investigator: dr hab. Agnieszka Kobielak

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  17. Elucidating the molecular background of disorders of sex development in dogs by comprehensive analysis of gonadal transc...

    Call: OPUS 26 , Panel: NZ9

    Principal investigator: prof. Marek Zbigniew Świtoński

    Uniwersytet Przyrodniczy w Poznaniu, Wydział Medycyny Weterynaryjnej i Nauk o Zwierzętach

  18. Role of chromatin loops in transcription attenuation and termination

    Call: PRELUDIUM BIS 5 , Panel: NZ2

    Principal investigator: dr hab. Michał Ryszard Gdula

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Centrum Zaawansowanych Technologii

  19. Deciphering the Chemoproteomics and Chemotranscriptomics of Anti-Alzheimer Drugs for Novel Druggable Target Identificati...

    Call: WEAVE-UNISONO , Panel: NZ5

    Principal investigator: prof. Krzysztof Sobczak

    Uniwersytet im. Adama Mickiewicza w Poznaniu

  20. Biomaterials inducing DNA demethylation as tools for future neuron regeneration therapies

    Call: OPUS 25 , Panel: ST8

    Principal investigator: dr hab. Katarzyna Nawrotek

    Politechnika Warszawska

  21. Elucidating molecular mechanisms of the crosstalk between the muscle and the brain during physical activity in obesity

    Call: OPUS 25 , Panel: NZ9

    Principal investigator: prof. Joanna Helena Śliwowska

    Uniwersytet Przyrodniczy w Poznaniu, Wydział Medycyny Weterynaryjnej i Nauk o Zwierzętach

  22. Epigenetic biomarkers of destruction of residual beta cells after diagnosis of type 1 diabetes – links to diabetic ketoa...

    Call: PRELUDIUM 22 , Panel: NZ5

    Principal investigator: Arkadiusz Mariusz Michalak

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  23. Investigating the mechanisms of epigenetic memory at the example of the responsiveness of human immune cells to vitamin ...

    Call: OPUS 25 , Panel: NZ9

    Principal investigator: prof. Carsten Johannes Carlberg

    Instytut Rozrodu Zwierząt i Badań Żywności Polskiej Akademii Nauk

  24. Selective PPARγ modulation by amorfrutin B as a novel therapeutic approach to chemotherapy-induced damage to mammalian b...

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Bernadeta Angelika Pietrzak-Wawrzyńska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  25. Traces of memory in the clonal plant network: effects of epigenetic variability on plant adaptation to drought or a path...

    Call: PRELUDIUM 22 , Panel: NZ8

    Principal investigator: Wojciech Robert Wysoczański

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  26. Spatial Determinants of Immunotherapy Resistance in Cancer

    Call: WEAVE-UNISONO , Panel: NZ6

    Principal investigator: dr Marcin Tabaka

    Instytut Chemii Fizycznej Polskiej Akademii Nauk

  27. The role of genome architecture and related chromatin modifications in innate immune transcriptional memory of antigen p...

    Call: Polskie Powroty NAWA 2022 , Panel: NZ2

    Principal investigator: dr Paweł Sławomir Mikulski

    Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk - Imol

  28. Blood plasma microRNA profile as a basis for detecting Alzheimer's disease and dementia risk in pre-symptomatic individu...

    Call: OPUS 24 , Panel: NZ7

    Principal investigator: prof. Urszula Wojda

    Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

  29. Effect of embryonic signals on methylome of the porcine endometrium as a novel mechanism contributing to pregnancy estab...

    Call: OPUS 24 , Panel: NZ9

    Principal investigator: prof. Agnieszka Wacławik

    Instytut Rozrodu Zwierząt i Badań Żywności Polskiej Akademii Nauk

  30. Cytomolecular insight into Lupinus genomes

    Call: OPUS 2 , Panel: NZ2

    Principal investigator: dr Karolina Susek

    Instytut Genetyki Roślin Polskiej Akademii Nauk

  31. The impact of early life environment and (epi)genetics on animal cognition using a neuroepigenetic approach

    Call: PRELUDIUM BIS 4 , Panel: NZ8

    Principal investigator: dr hab. Irene Camerlink

    Instytut Genetyki i Hodowli Zwierząt Polskiej Akademii Nauk

  32. GENETIC AND EPIGENETIC BACKGROUND OF ANTIBODY PRODUCTION DEFECTS IN CHILDREN– IN SEARCH OF A PATHOPHYSIOLOGICAL MODEL OF...

    Call: OPUS 24 , Panel: NZ6

    Principal investigator: dr hab. Aleksandra Anna Szczawińska-Popłonyk

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  33. The discovery of multifactorial regulation at epigenetic memory of active gene expression state

    Call: SONATA 18 , Panel: NZ2

    Principal investigator: dr Paweł Sławomir Mikulski

    Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

  34. Mechanisms for Establishment of Transcriptional Memory

    Call: SONATA 18 , Panel: NZ1

    Principal investigator: dr Wojciech Siwek

    Uniwersytet Gdański, Międzynarodowe Centrum Badań nad Szczepionkami Przeciwnowotworowymi

  35. Decoding "metabolic memory" - how do glycemic control and variability affect epigenetic changes in young people with typ...

    Call: PRELUDIUM BIS 4 , Panel: NZ5

    Principal investigator: prof. Wojciech Maksymilian Fendler

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  36. Elucidating the contribution of non-coding genomic elements to heart development and disease at single-cell resolution

    Call: OPUS 24 , Panel: NZ2

    Principal investigator: dr hab. Cecilia Lanny Winata

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej w Warszawie

  37. Environmental and epigenetic modifications and atopy and allergic diseases prevention in rural population at all ages - ...

    Call: OPUS 24 , Panel: NZ7

    Principal investigator: dr hab. Barbara Ewa Sozańska

    Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu

  38. Impact of lipid metabolism on histone acetylation during mouse embryo development.

    Call: PRELUDIUM BIS 4 , Panel: NZ3

    Principal investigator: dr Domenico Iuso

    Instytut Genetyki i Hodowli Zwierząt Polskiej Akademii Nauk

  39. The effect of maternal treatment with metformin in pregnancy and lactation on programming metabolic adverse conditions i...

    Call: SONATA BIS 12 , Panel: NZ7

    Principal investigator: dr hab. Monika Słupecka-Ziemilska

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

  40. Comprehensive, multimodal profiling of chromatin states and gene expression in single cells.

    Call: SONATA BIS 12 , Panel: NZ2

    Principal investigator: dr Marcin Tabaka

    Instytut Chemii Fizycznej Polskiej Akademii Nauk, Międzynarodowe Centrum Badań Oka

  41. Defining (sex and age) cell-specific epigenetic mechanisms underlying EnvironmentalEnrichment/Exercise as non-pharmacolo...

    Call: WEAVE-UNISONO , Panel: NZ2

    Principal investigator: dr hab. Bartosz Wilczyński

    Uniwersytet Warszawski

  42. Molecular Mechanisms of Dietary Intervention on Neurodegeneration

    Call: WEAVE-UNISONO , Panel: NZ2

    Principal investigator: dr hab. Maciej Figiel

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  43. The role of lipoproteins and lipoprotein receptors in mediating the effects of childhood trauma on the brain and the ger...

    Call: PRELUDIUM 21 , Panel: NZ3

    Principal investigator: Weronika Tomaszewska

    Sieć Badawcza ŁUKASIEWICZ - PORT Polski Ośrodek Rozwoju Technologii

  44. The role of epigenetic modifications in Gli3R-dependent Hedgehog pathway repression

    Call: PRELUDIUM 21 , Panel: NZ3

    Principal investigator: Weronika Anna Skarżyńska

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  45. Selective modulation of PPARγ signaling as a new therapeutic strategy for Alzheimer's disease

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: Karolina Barbara Przepiórska-Drońska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  46. Pharmacogenomics of SGLT2 inhibitors - investigating the role of empagliflozin in epigenetic modification of non-coding ...

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: Anna Nowak-Szwed

    Warszawski Uniwersytet Medyczny

  47. The effects of proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors on changes in selected epigenetic mechan...

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: Agnieszka Magdalena Woźniak

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  48. N6-methyladenosine (m6A) RNA modification as a putative metabolic switch between cell survival and cell death in induced...

    Call: PRELUDIUM 21 , Panel: NZ9

    Principal investigator: Elżbieta Marta Rudy

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  49. Transgenerational inheritance of Liver Disease in mouse offspring conceived by Assisted Reproduction Technologies.

    Call: SONATINA 6 , Panel: NZ4

    Principal investigator: dr Maria Florencia Heber

    Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

  50. Analysis of expression levels as well as genetic and epigenetic changes of GRHL genes in human non-melanoma skin cancers...

    Call: PRELUDIUM 2 , Panel: NZ5

    Principal investigator: Agnieszka Kikulska

    Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk