Projects funded by the NCN


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236 projects found matching your search criteria :

  1. The role of DNA methylation in therapy that increases CFTR channel activity in cystic fibrosis

    Call: SONATA 20 , Panel: NZ5

    Principal investigator: dr Beata Maria Narożna

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  2. OVO-AGE: Deciphering the code for ageing and longevity in the bovine oocyte with the help of multi-omics, telomeres, and...

    Call: OPUS 28 , Panel: NZ9

    Principal investigator: dr hab. Pawel Kordowitzki

    Uniwersytet Mikołaja Kopernika

  3. Mind the gap! Plasmonic nanocavity for spectroscopic trapping of local molecularrearrangements in DNA upon epigenetic mo...

    Call: OPUS 28 , Panel: ST4

    Principal investigator: prof. Ewelina Wioletta Lipiec

    Uniwersytet Jagielloński

  4. The role of EZH2 activity in the development of resistance to targeted therapy in melanoma

    Call: OPUS 28 , Panel: NZ7

    Principal investigator: dr Michał Jerzy Woźniak

    Uniwersytet Medyczny w Łodzi

  5. The role of oral vitamin C supplementation in the epigenetic regulation of male fertility - finding the missing puzzles

    Call: OPUS 28 , Panel: NZ7

    Principal investigator: dr hab. Monika Frączek

    Instytut Genetyki Człowieka PAN

  6. Revealing the component of epigenetic ageing in monocarpic plant leaves

    Call: SONATA 20 , Panel: NZ9

    Principal investigator: dr Magda Dominika Grabsztunowicz

    Uniwersytet im. Adama Mickiewicza w Poznaniu

  7. The H3K27M oncohistone-centred molecular mechanisms as therapeutic targets in pediatric malignant diffuse midline glioma...

    Call: SONATA BIS 14 , Panel: NZ3

    Principal investigator: dr Katarzyna Leszczyńska

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  8. Exploring DMRTA2 in Glioblastoma: Epigenetic Regulation, Angiogenesis Disruption, and Biomarker Development

    Call: SONATA BIS 14 , Panel: NZ3

    Principal investigator: dr Marta Magdalena Maleszewska-Bobińska

    Uniwersytet Warszawski

  9. M6A RNA methylation signatures as a targets for HPV-dependent HNSCC therapy

    Call: OPUS 27 , Panel: NZ5

    Principal investigator: Kamila Ostrowska

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  10. N6-methyladenine metabolism - potential relationships with the development of hematological malignancies.

    Call: OPUS 27 , Panel: NZ5

    Principal investigator: dr Marta Starczak

    Uniwersytet Mikołaja Kopernika

  11. Clonal and epigenetic pathways in the development of pediatric acute lymphoblastic leukemia.

    Call: PRELUDIUM 23 , Panel: NZ5

    Principal investigator: Jadwiga Maria Filipek-Gorzała

    Uniwersytet Jagielloński

  12. From methylation to malformation: the role of DNA methylation in the pathogenesis of Klippel-Feil syndrome

    Call: PRELUDIUM 23 , Panel: NZ5

    Principal investigator: Anna Szoszkiewicz

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  13. Using DNA methylation markers and epigenetic clocks as an innovative tool to assess health, risk indicators, and manage ...

    Call: OPUS 27 , Panel: NZ7

    Principal investigator: dr hab. Ewelina Maria Pośpiech

    Pomorski Uniwersytet Medyczny w Szczecinie

  14. Using genetic and epigenetic data to predict human facial features – developing a theoretical basis for face prediction....

    Call: OPUS 27 , Panel: NZ8

    Principal investigator: prof. Wojciech Branicki

    Uniwersytet Jagielloński

  15. Impact of vitamin D on the epigenetic programming of CD34+ hematopoietic progenitor cells derived from human cord blood

    Call: OPUS 27 , Panel: NZ2

    Principal investigator: prof. Carsten Johannes Carlberg

    Instytut Rozrodu Zwierząt i Badań Żywności PAN

  16. Searching for novel genetic and epigenetic factors predisposing to osteoarthritis

    Call: OPUS 2 , Panel: NZ2

    Principal investigator: dr hab. Malwina Czarny-Ratajczak

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski I

  17. Semaglutide and neurodevelopment: investigating risks arising from prenatal exposure to a widely popular drug for diabet...

    Call: OPUS 26 , Panel: NZ7

    Principal investigator: dr Agnieszka Wnuk

    Instytut Farmakologii PAN

  18. Defining the transcriptional and epigenetic state of tumor cells with increased plasticity and the epithelial-endothelia...

    Call: OPUS 26 , Panel: NZ5

    Principal investigator: dr hab. Agnieszka Kobielak

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  19. Elucidating the molecular background of disorders of sex development in dogs by comprehensive analysis of gonadal transc...

    Call: OPUS 26 , Panel: NZ9

    Principal investigator: prof. Marek Zbigniew Świtoński

    Uniwersytet Przyrodniczy w Poznaniu, Wydział Medycyny Weterynaryjnej i Nauk o Zwierzętach

  20. Role of chromatin loops in transcription attenuation and termination

    Call: PRELUDIUM BIS 5 , Panel: NZ2

    Principal investigator: dr hab. Michał Ryszard Gdula

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Centrum Zaawansowanych Technologii

  21. Deciphering the Chemoproteomics and Chemotranscriptomics of Anti-Alzheimer Drugs for Novel Druggable Target Identificati...

    Call: JPND Call 2023 , Panel: NZ5

    Principal investigator: prof. Krzysztof Sobczak

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  22. Biomaterials inducing DNA demethylation as tools for future neuron regeneration therapies

    Call: OPUS 25 , Panel: ST8

    Principal investigator: dr hab. Katarzyna Nawrotek

    Politechnika Warszawska

  23. Elucidating molecular mechanisms of the crosstalk between the muscle and the brain during physical activity in obesity

    Call: OPUS 25 , Panel: NZ9

    Principal investigator: prof. Joanna Helena Śliwowska

    Uniwersytet Przyrodniczy w Poznaniu, Wydział Medycyny Weterynaryjnej i Nauk o Zwierzętach

  24. Epigenetic biomarkers of destruction of residual beta cells after diagnosis of type 1 diabetes – links to diabetic ketoa...

    Call: PRELUDIUM 22 , Panel: NZ5

    Principal investigator: Arkadiusz Mariusz Michalak

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  25. Investigating the mechanisms of epigenetic memory at the example of the responsiveness of human immune cells to vitamin ...

    Call: OPUS 25 , Panel: NZ9

    Principal investigator: prof. Carsten Johannes Carlberg

    Instytut Rozrodu Zwierząt i Badań Żywności PAN

  26. Selective PPARγ modulation by amorfrutin B as a novel therapeutic approach to chemotherapy-induced damage to mammalian b...

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Bernadeta Angelika Pietrzak-Wawrzyńska

    Instytut Farmakologii PAN

  27. Traces of memory in the clonal plant network: effects of epigenetic variability on plant adaptation to drought or a path...

    Call: PRELUDIUM 22 , Panel: NZ8

    Principal investigator: Wojciech Robert Wysoczański

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  28. Spatial Determinants of Immunotherapy Resistance in Cancer

    Call: WEAVE-UNISONO , Panel: NZ6

    Principal investigator: dr Marcin Tabaka

    Instytut Chemii Fizycznej Polskiej Akademii Nauk, Międzynarodowe Centrum Badań Oka

  29. The role of genome architecture and related chromatin modifications in innate immune transcriptional memory of antigen p...

    Call: Polskie Powroty NAWA 2022 , Panel: NZ2

    Principal investigator: dr Paweł Sławomir Mikulski

    Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk - Imol

  30. Blood plasma microRNA profile as a basis for detecting Alzheimer's disease and dementia risk in pre-symptomatic individu...

    Call: OPUS 24 , Panel: NZ7

    Principal investigator: prof. Urszula Wojda

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  31. Effect of embryonic signals on methylome of the porcine endometrium as a novel mechanism contributing to pregnancy estab...

    Call: OPUS 24 , Panel: NZ9

    Principal investigator: prof. Agnieszka Wacławik

    Instytut Rozrodu Zwierząt i Badań Żywności PAN

  32. Cytomolecular insight into Lupinus genomes

    Call: OPUS 2 , Panel: NZ2

    Principal investigator: dr Karolina Susek

    Instytut Genetyki Roślin PAN

  33. The impact of early life environment and (epi)genetics on animal cognition using a neuroepigenetic approach

    Call: PRELUDIUM BIS 4 , Panel: NZ8

    Principal investigator: dr hab. Irene Camerlink

    Instytut Genetyki i Hodowli Zwierząt PAN

  34. GENETIC AND EPIGENETIC BACKGROUND OF ANTIBODY PRODUCTION DEFECTS IN CHILDREN– IN SEARCH OF A PATHOPHYSIOLOGICAL MODEL OF...

    Call: OPUS 24 , Panel: NZ6

    Principal investigator: dr hab. Aleksandra Anna Szczawińska-Popłonyk

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  35. The discovery of multifactorial regulation at epigenetic memory of active gene expression state

    Call: SONATA 18 , Panel: NZ2

    Principal investigator: dr Paweł Sławomir Mikulski

    Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

  36. Mechanisms for Establishment of Transcriptional Memory

    Call: SONATA 18 , Panel: NZ1

    Principal investigator: dr Wojciech Siwek

    Uniwersytet Gdański, Międzynarodowe Centrum Badań nad Szczepionkami Przeciwnowotworowymi

  37. Decoding "metabolic memory" - how do glycemic control and variability affect epigenetic changes in young people with typ...

    Call: PRELUDIUM BIS 4 , Panel: NZ5

    Principal investigator: prof. Wojciech Maksymilian Fendler

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  38. Elucidating the contribution of non-coding genomic elements to heart development and disease at single-cell resolution

    Call: OPUS 24 , Panel: NZ2

    Principal investigator: dr hab. Cecilia Lanny Winata

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

  39. Environmental and epigenetic modifications and atopy and allergic diseases prevention in rural population at all ages - ...

    Call: OPUS 24 , Panel: NZ7

    Principal investigator: dr hab. Barbara Ewa Sozańska

    Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej

  40. Impact of lipid metabolism on histone acetylation during mouse embryo development.

    Call: PRELUDIUM BIS 4 , Panel: NZ3

    Principal investigator: dr Domenico Iuso

    Instytut Genetyki i Hodowli Zwierząt PAN

  41. The effect of maternal treatment with metformin in pregnancy and lactation on programming metabolic adverse conditions i...

    Call: SONATA BIS 12 , Panel: NZ7

    Principal investigator: dr hab. Monika Słupecka-Ziemilska

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  42. Comprehensive, multimodal profiling of chromatin states and gene expression in single cells.

    Call: SONATA BIS 12 , Panel: NZ2

    Principal investigator: dr Marcin Tabaka

    Instytut Chemii Fizycznej Polskiej Akademii Nauk, Międzynarodowe Centrum Badań Oka

  43. Defining (sex and age) cell-specific epigenetic mechanisms underlying EnvironmentalEnrichment/Exercise as non-pharmacolo...

    Call: JPND Call 2022 , Panel: NZ2

    Principal investigator: dr hab. Bartosz Zbigniew Wilczyński

    Uniwersytet Warszawski

  44. Molecular Mechanisms of Dietary Intervention on Neurodegeneration

    Call: JPND Call 2022 , Panel: NZ2

    Principal investigator: dr hab. Maciej Figiel

    Instytut Chemii Bioorganicznej PAN

  45. The role of lipoproteins and lipoprotein receptors in mediating the effects of childhood trauma on the brain and the ger...

    Call: PRELUDIUM 21 , Panel: NZ3

    Principal investigator: Weronika Tomaszewska

    Sieć Badawcza ŁUKASIEWICZ - PORT Polski Ośrodek Rozwoju Technologii

  46. The role of epigenetic modifications in Gli3R-dependent Hedgehog pathway repression

    Call: PRELUDIUM 21 , Panel: NZ3

    Principal investigator: Weronika Anna Skarżyńska

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  47. Selective modulation of PPARγ signaling as a new therapeutic strategy for Alzheimer's disease

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: Karolina Barbara Przepiórska-Drońska

    Instytut Farmakologii PAN

  48. Pharmacogenomics of SGLT2 inhibitors - investigating the role of empagliflozin in epigenetic modification of non-coding ...

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: Anna Nowak-Szwed

    Warszawski Uniwersytet Medyczny

  49. The effects of proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors on changes in selected epigenetic mechan...

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: Agnieszka Magdalena Woźniak

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  50. N6-methyladenosine (m6A) RNA modification as a putative metabolic switch between cell survival and cell death in induced...

    Call: PRELUDIUM 21 , Panel: NZ9

    Principal investigator: Elżbieta Marta Rudy

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii