Zmiana języka

Projects search

Maternal obesity and epigenetic programming: from gametogenesis to early embryo development

2016/23/B/NZ4/03737

Keywords

Descriptors

  • NZ2_2: Genomika, transkryptomika i epigenomika
  • NZ4_11: Metabolizm
  • NZ4_6: Endokrynologia

Panel

NZ4 – Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution

Instytut Rozrodu Zwierząt i Badań Żywności PAN

Voivodeship: warmińsko-mazurskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Antonio Miguel Galvao

Number of co-investigators in the project: 4

Call

OPUS 12 – announced on 2016-09-15

Amount awarded
795 756 PLN
Project start date
2017-08-24
Project end date
2021-08-23
Project duration
48 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (3)

  1. Leptin signaling in the ovary of diet-induced obese mice regulates activation of NOD-like receptor protein 3 inflammasome

    Authors:
    Adamowski, Marek; Wołodko, Karolina; Oliveira, Joana; Castillo-Fernandez, Juan; Murta, Daniel; Kelsey, Gavin; Galvão, António M.
    Academic press:
    Frontiers in Cell and Developmental Biology (year: 2021, volume: 9, pages: art. no 738731 (1-17)), Publisher: Frontiers
    Status:
    Published
    DOI:
    10.3389/fcell.2021.738731 – link to the publication

  2. Revisiting the impact of local leptin signaling in folliculogenesis and oocyte maturation in obese mothers

    Authors:
    Wołodko, Karolina; Castillo-Fernandez, Juan; Kelsey, Gavin; Galvão, António M.
    Academic press:
    International Journal of Molecular Sciences (year: 2021, volume: 22(5), pages: art. no 4270 (1-26)), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22084270 – link to the publication

  3. Leptin Resistance in the Ovary of Obese Mice is Associated with Profound Changes in the Transcriptome of Cumulus Cells

    Authors:
    WOŁODKO, Karolina; WALEWSKA, Edyta; ADAMOWSKI, Marek; CASTILLO-FERNANDEZ, Juan; KELSEY, Gavin; GALVÃO, António M.
    Academic press:
    Journal of Cellular Physiology and Biochemistry (year: 2020, volume: 54, pages: 417-437), Publisher: Journal of Cellular Physiology and Biochemistry
    Status:
    Published
    DOI:
    10.33594/000000228 – link to the publication

Articles in post-conference publications (7)

  1. Obesity Alters Leptin Signalling in Mouse Uterus: Putative Link with Impaired Decidualisation

    Authors:
    Walewska E, Witek K, Kelsey G, Pérez-Garcia V, Galvão A
    Conference:
    Placental Biology course, Centre for Trophoblast Research (year: 2021, pages: 31), Publisher: Cambridge University
    Date:
    conference 9th July 2021
    Status:
    Published

  2. How Maternal Obesity Affects the Oocyte Epigenome and Preimplantation Embryos

    Authors:
    António Galvão, Stephen Clark, Gavin Kelsey
    Conference:
    3rd Danube COnference on Epigenetics (year: 2018, pages: https://epigenetics2018.febsevents.org/), Publisher: FEBS
    Date:
    conference 9-12 October 2018
    Status:
    Published

  3. Maternal obesity affects the epigenome of oocytes and preimplantation embryos.

    Authors:
    Galvão A, Clark S, Kelsey G
    Conference:
    Advances at the interface between metabolism and epigenetics (year: 2019, pages: brak), Publisher: Robinson College
    Date:
    conference 43481
    Status:
    Published

  4. Impaired Decidualisation in Obese Mice is Associated with Altered Uterine Leptin Signalling

    Authors:
    Walewska E, Witek K, Kelsey G, Pérez-Garcia V, Galvão A
    Conference:
    9th Congress of the Society for Reproductive Biology (year: 2021, pages: PpS 55), Publisher: TBR
    Date:
    conference 02-04.09.2021, Poznań
    Status:
    Published

  5. Obesity Alters Leptin Signalling in Mouse Uterus: Putative Link to Epigenetic Regulation during Decidualisation

    Authors:
    Walewska E, Witek K, Kelsey G, Galvão A
    Conference:
    Centre for Trophoblast Research Annual Conference (year: 2019, pages: brak), Publisher: Bioscientifica
    Date:
    conference 43654
    Status:
    Published

  6. Effects of maternal obesity on oocyte methylome are reflected on blastocyst epigenome

    Authors:
    Galvão A, Clark S, Wolodko K, Castillo-Fernandez J, Kelsey G
    Conference:
    Mechanisms and Evolution of Intergenerational Change (year: 2019, pages: ppS45), Publisher: Wellcome Trust Genome Campus
    Date:
    conference 43732
    Status:
    Published

  7. Maternal Obesity Affects the Oocyte Epigenome in Mice

    Authors:
    António Galvão , Karolina Wolodko, Marek Adamowski, Stephen Clark, Gavin Kelsey
    Conference:
    51st Society for Study of Reproduction Meeting, New Orleans, USA (year: 2018, pages: https://portal.ssr.org/portal/events/), Publisher: Biology of Reproduction
    Date:
    conference 10-13 July 2018
    Status:
    Published

« New search

Graphic design and implementation: Jakub Piotrowski