Study of the effect of 17-beta estradiol on expression of gene encoding hypoxia inducible factor - 1 alpha (HIF-1 alpha) by epigenetic mechanisms in carcinogenesis of colorectal cancer.

2012/05/N/NZ5/00844

Keywords

Descriptors

  • NZ1_1: Biologia molekularna
  • NZ3_1: Biologia komórki
  • NZ5_3: Patogeneza chorób człowieka

Panel

NZ5 – Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski I

Voivodeship: wielkopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Agnieszka Anna Rawłuszko-Wieczorek

Number of co-investigators in the project: 3

Call

PRELUDIUM 3 – announced on 2012-03-15

Amount awarded
150 000 PLN
Project start date
2013-01-29
Project end date
2016-01-28
Project duration
36 months (the same as in the proposal)
Project status
Project settled

Information in the final report

Publication in academic press/journals (4)

  1. Significance of intratissue estrogen concentration coupled with estrogen receptors levels in colorectal cancer prognosis

    Authors:
    Agnieszka Anna Rawłuszko-Wieczorek, Łukasz Marczak, Nikodem Horst, Karolina Horbacka, Piotr Krokowicz, Paweł Piotr Jagodziński
    Academic press:
    Oncotarget (year: 2017, volume: 8, pages: 115546-115560), Publisher: oncotarget
    Status:
    Published
    DOI:
    10.18632/oncotarget.23309 – link to the publication
  2. TET proteins in cancer: Current 'state of the art'

    Authors:
    Rawłuszko-Wieczorek AA, Siera A, Jagodziński PP
    Academic press:
    Critical Reviews in Oncology/Hematology (year: 2015, volume: 96, pages: 425-436), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.critrevonc.2015.07.008 – link to the publication
  3. Clinical significance of DNA methylation mRNA levels of TET family members in colorectal cancer.

    Authors:
    Rawłuszko-Wieczorek AA, Siera A, Horbacka K, Horst N, Krokowicz P, Jagodziński PP.
    Academic press:
    Journal of Cancer Research and Clinical Oncology (year: 2015, volume: 141, pages: 1379-1392), Publisher: Springer
    Status:
    Published
    DOI:
    10.1007/s00432-014-1901-2 – link to the publication
  4. Prognostic potential of DNA methylation and transcript levels of HIF1A and EPAS1 in colorectal cancer

    Authors:
    Rawłuszko-Wieczorek AA, Horbacka K, Krokowicz P, Misztal M, Jagodziński PP
    Academic press:
    Molecular Cancer Research (year: 2014, volume: 12, pages: 1112-1127), Publisher: American Association for Cancer Research, Inc
    Status:
    Published
    DOI:
    10.1158/1541-7786.MCR-14-0054 – link to the publication

Articles in post-conference publications (2)

  1. Significance of DNA methylation in regulation of hypoxia-inducible factor -3a expression in colorectal cancer

    Authors:
    Rawłuszko-Wieczorek AA, Bujnicka KE, Horbacka K, Krokowicz P, Jagodzińnski PP
    Conference:
    FEBS EMBO 2014 Conference (year: 2014, pages: 310), Publisher: Wiley
    Date:
    conference 30.08.2014-3.09.2014
    Status:
    Published
    DOI:
    link to the publication
  2. Epigenetic regulation of hypoxia-inducible factor -3α (HIF-3α) expression in colorectal cancer

    Authors:
    Rawłuszko-Wieczorek AA, Bujnicka KE, Horbacka K, Horst N, Krokowicz P, Jagodzińnski PP
    Conference:
    23rd Congress of the International Union of Biochemistry and Molecular Biology (IUBMB) and 44th Annual Meeting of the Brazilian Society for Biochemistry and Molecular Biology – SBBq (year: 2015, pages: 167), Publisher: Brazilian Society for Biochemistry and Molecular Biology
    Date:
    conference 24.08-28.08.2015
    Status:
    Published

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