Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Epigenetic regulation of DDR1 and IKK beta in renal carcinoma cell lines - a role of micro-RNA-199a-5p and micro-RNA-199b-5p in the pathogenesis of clear cell renal cell carcinoma

2012/05/B/NZ4/01832

Keywords:

clear cell renal cell carcinoma micro-RNA epigenetics

Descriptors:

  • NZ2_2: Genomics, transcriptomics, epigenomics

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Nauk Medycznych

woj. warmińsko-mazurskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Jolanta Kiewisz 

Number of co-investigators in the project: 5

Call: OPUS 3 - announced on 2012-03-15

Amount awarded: 349 700 PLN

Project start date (Y-m-d): 2013-03-06

Project end date (Y-m-d): 2016-09-05

Project duration:: 42 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. COUNTESS II FL AUTOMATED CELL COUNTER.

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (4)
  1. Altered expression of DDR1 in clear cell renal cell carcinoma correlates with miR-199a/b-5p and patients' outcome
    Authors:
    Bartlomiej E. Krazinski, Jolanta Kiewisz, Agnieszka Sliwinska-Jewsiewicka, Anna E. Kowalczyk, Jedrzej Grzegrzolka, Janusz Godlewski, Przemyslaw Kwiatkowski, Piotr Dziegiel, Zbigniew Kmiec,
    Academic press:
    Cancer Genomics and Proteomics (rok: 2019, tom: 16, strony: 179-193), Wydawca: The International Institute of Anticancer Research
    Status:
    Published
    DOI:
    10.21873/cgp.20124 - link to the publication
  2. SATB1 is Down-regulated in Clear Cell Renal Cell Carcinoma and Correlates with miR-21-5p Overexpression and Poor Prognosis
    Authors:
    Kowalczyk AE, Krazinski BE, Godlewski J, Grzegrzolka J, Kiewisz J, Kwiatkowski P, Sliwinska-Jewsiewicka A, Dziegiel P, Kmiec Z
    Academic press:
    Cancer genomics and proteomics (rok: 2016, tom: 13, strony: 209-217), Wydawca: International Institute of Anticancer Research, ANTICANCER RESEARCH USA, Inc.
    Status:
    Published
  3. IKBKB expression in clear cell renal cell carcinoma is associated with tumor grade and patient outcomes
    Authors:
    Bartlomiej E. Krazinski, Anna E. Kowalczyk, Agnieszka Sliwinska-Jewsiewicka, Jedrzej Grzegrzolka2, Janusz Godlewski, Przemyslaw Kwiatkowski, Piotr Dziegiel, Zbigniew Kmiec, Jolanta Kiewisz
    Academic press:
    Oncology reports (rok: 2019, tom: 41, strony: 1189-1197), Wydawca: Spandidos Publications Ltd., Athens, Greece
    Status:
    Published
    DOI:
    10.3892/or.2018.6872 - link to the publication
  1. IKBKB Expression is an Independent Prognostic Factor in Clear Cell Renal Cell Carcinoma
    Authors:
    Bartłomiej E. Kraziński , Jolanta Kiewisz , Janusz Godlewski , Anna E. Kowalczyk , Agnieszka ŚliwinskaJewsiewicka , Przemysław Kwiatkowski , Jędrzej Grzegrzółka , Piotr Dzięgiel , Zbigniew Kmieć
    Conference:
    The 42nd annual Congress of the International Society of Oncology and BioMarkers (rok: 2015, ), Wydawca: International Society of Oncology and BioMarkers
    Data:
    konferencja 3-7.10.2015
    Status:
    Published
  2. Significance of microRNA-199a-5p and microRNA-199b-5p and their target genes in renal cancer cells
    Authors:
    Bartlomiej E. Krazinski, Jolanta Kiewisz, Agnieszka Sliwinska-Jewsiewicka, Anna E. Kowalczyk. Janusz Godlewski, Przemyslaw Kwiatkowski, Zbigniew Kmiec
    Conference:
    EUROBIOTECH CONGRESS (rok: 2017, ), Wydawca: Targi w Krakowie Sp. z o.o.
    Data:
    konferencja 11-14 września
    Status:
    Published
  3. The expression of discoidin domain receptor 1 (DDR1) correlates with the progression of clear cell renal cell carcinoma
    Authors:
    Jolanta Kiewisz, Bartłomiej E. Kraziński, Jędrzej Grzegrzółka, Janusz Godlewski, Anna E. Kowalczyk, Agnieszka Śliwińska-Jewsiewicka, Przemysław Kwiatkowski, Piotr Dzięgiel, Zbigniew Kmieć
    Conference:
    49th Symposium of The Polish Society for Histochemistry and Cytochemistry:"Współczesne techniki mikroskopowe i molekularne w biologii i medycynie" (rok: 2015, ), Wydawca: Materiały konferencyjne PTHiC
    Data:
    konferencja 09-12.09.2015 r.
    Status:
    Published
  4. The expression of discoidin domain receptor 1 (DDR1) protein in clear cell renal cell carcinoma
    Authors:
    Kraziński BE, Kiewisz J, Godlewski J, Kowalczyk AE, Śliwińska-Jewsiewicka A, Kwiatkowski P, Kmieć Z
    Conference:
    48th Symposium of The Polish Society for Histochemistry and Cytochemistry: "Od MAKRO do NANO - Nowe horyzonty i nowe możliwości w naukach podstawowych i klinicznych" (rok: 2014, ), Wydawca: Materiały konferencyjne PTHiC
    Data:
    konferencja 03.09 - 06.09
    Status:
    Published