Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Epigenetic regulation of pro-epileptic protease Matrix Metalloproteinase-9 expression in the hippocampus during epileptogenesis

2011/01/B/NZ2/05281

Keywords:

MMP-9 epilepsy DNA methylation miRNA hippocampus gene expression epigenetics

Descriptors:

  • NZ2_2: Genomics, transcriptomics, epigenomics
  • NZ1_1: Molecular biology
  • NZ2_1: Molecular genetics

Panel:

NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution :

CENTRUM MEDYCZNE KSZTAŁCENIA PODYPLOMOWEGO

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Marcin Rylski 

Number of co-investigators in the project: 7

Call: OPUS 1 - announced on 2011-03-15

Amount awarded: 699 998 PLN

Project start date (Y-m-d): 2011-12-07

Project end date (Y-m-d): 2014-12-06

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. aparat do elektroforezy agarozowej: Sub-Cell Model 96 Cell (Bio-Rad) (4 500 PLN)
  2. urządzenie do ekstrakcji miRNA: flashPAGE Fractionator Apparatus (Ambion) (4 000 PLN)
  3. aparat do elektroforezy poliakrylamidowej: PROTEAN II xi | XL Vertical Electrophoresis Cells (Bio-Rad) (7 800 PLN)
  4. Aparat do transferu bialek na membrany na mokro(Bio- Rad).
  5. zasilacz: Power Pack Uniwersal (Bio-Rad) (10 000 PLN)

Information in the final report

  • Publication in academic press/journals (1)
  • Articles in post-conference publications (1)
  1. Epigenetics of Epileptogenesis-Evoked Upregulation of Matrix Metalloproteinase-9 in Hippocampus
    Authors:
    Katarzyna Zybura-Broda, Renata Amborska, Magdalena Ambrozek-Latecka, Joanna Wilemska, Agnieszka Bogusz, Joanna Bucko, Anna Konopka, Wieslawa Grajkowska, Marcin Roszkowski, Andrzej Marchel, Andrzej Rysz, Lukasz Koperski, Grzegorz M. Wilczynski, Leszek Kaczmarek, Marcin Rylski
    Academic press:
    PLoS One (rok: 2016, tom: b.d, strony: b.d), Wydawca: Public Library of Science
    Status:
    Published
    DOI:
    10.1371/journal.pone.0159745. - link to the publication
  1. DNA methylation regulates expression of pro-epileptic protease MMP-9 during epileptogenesis
    Authors:
    Żybura-Broda K., Amborska R., Bućko J., Kaczmarek L., Rylski M.
    Conference:
    FENS Featured Regional Meeting Prague 2013 (rok: 2013, ), Wydawca: Institute of Experimental Medicine AS CR, v.v.i., Vídeňská 1083, Prague 4
    Data:
    konferencja 11–14 września
    Status:
    Published

O Narodowym Centrum Nauki

Finansowanie nauki

Współpraca zagraniczna

Centrum prasowe

Deklaracja dostępności
Przetwarzanie danych osobowych
Polityka cookies

Partnerzy