Projects funded by the NCN


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54 projects found matching your search criteria :

  1. Identification and structural characterization of the primordial cytotoxic conformers of the amyloidogenic cascade: Idea...

    Call: UNISONO , Panel: NZ1

    Principal investigator: prof. Marek Cieplak

    Instytut Fizyki PAN

  2. DNA repair pathways contributing to resistance to photodynamic therapy and as possible theraupeutic targets

    Call: OPUS 8 , Panel: NZ5

    Principal investigator: dr hab. Elżbieta Speina

    Instytut Biochemii i Biofizyki PAN

  3. Research on human eosinophils as a potential therapeutic target.

    Call: PRELUDIUM 7 , Panel: NZ7

    Principal investigator: Marek Rafał Grosicki

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

  4. Analysis of relations on the level of metabolome, miRNome, and transcriptome of human renal cancer: towards identificati...

    Call: OPUS 7 , Panel: NZ5

    Principal investigator: dr hab. Agnieszka Piekiełko-Witkowska

    CENTRUM MEDYCZNE KSZTAŁCENIA PODYPLOMOWEGO

  5. GPR18 orphan receptor. Search for the tools to investigate GPR18 as potential therapeutic target

    Call: OPUS 6 , Panel: NZ7

    Principal investigator: prof. Katarzyna Justyna Kieć-Kononowicz

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

  6. Motor thalamic nuclei as a potential therapeutic target for adenosine in parkinsonian and essential tremor; behavioural,...

    Call: OPUS 6 , Panel: NZ4

    Principal investigator: dr hab. Jadwiga Wardas

    Instytut Farmakologii PAN

  7. BCL11b - Potential Therapeutic Target in T cell Neoplasms

    Call: OPUS 5 , Panel: NZ1

    Principal investigator: dr hab. Grzegorz Przybylski

    Instytut Genetyki Człowieka PAN

  8. The role of sphingosine-1-phosphate (S1P) receptors signaling in animal model of Parkinson disease. Searching of novel t...

    Call: PRELUDIUM 5 , Panel: NZ4

    Principal investigator: Joanna Agata Motyl

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  9. Evaluation of peroxiredoxins 1 and 2 along with the thioredoxin-thioredoxin reductase system as new therapeutic targets ...

    Call: OPUS 4 , Panel: NZ7

    Principal investigator: dr hab. Radosław Zagożdżon

    Warszawski Uniwersytet Medyczny, I Wydział Lekarski

  10. Identification of potential therapeutic targets in melanoma stem-like cells

    Call: HARMONIA 3 , Panel: NZ2

    Principal investigator: prof. Małgorzata Ewa Czyż

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski z Oddziałem Stomatologicznym

  11. PIM kinases as rational therapeutic targets in lymphoid malignancies.

    Call: OPUS 2 , Panel: NZ4

    Principal investigator: dr hab. Przemysław Juszczyński

    Instytut Hematologii i Transfuzjologii

  12. Targeted Degradation of the MLL Complex in Leukemia: A PROTAC-Based Therapeutic Strategy

    Call: SONATINA 9 , Panel: ST5

    Principal investigator: dr Natalia Anna Skrzypczak

    Fundacja Uniwersytetu im. Adama Mickiewicza

  13. Identifying early biomarkers and molecular targets for therapeutic intervention in right ventricular dysfunction

    Call: OPUS 28 , Panel: NZ5

    Principal investigator: prof. Przemysław Błyszczuk

    Uniwersytet Jagielloński

  14. Selective autophagy-mediated protein degradation as a potential therapeutic strategy for the treatment of inflammatory c...

    Call: OPUS 28 , Panel: NZ7

    Principal investigator: dr hab. Monika Emilia Marcinkowska

    Uniwersytet Jagielloński

  15. The H3K27M oncohistone-centred molecular mechanisms as therapeutic targets in pediatric malignant diffuse midline glioma...

    Call: SONATA BIS 14 , Panel: NZ3

    Principal investigator: dr Katarzyna Leszczyńska

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  16. CD147 as a novel multifunctional modulator of podocyte metabolism and exosome biogenesis: Identification of new molecula...

    Call: OPUS 27 , Panel: NZ4

    Principal investigator: dr hab. Agnieszka Piwkowska

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  17. Modulation of protein interaction networks as a new therapeutic target in the treatment of hereditary retinal dystrophie...

    Call: SONATA 19 , Panel: NZ5

    Principal investigator: dr Xiaonan Liu

    Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Medycznych w Katowicach

  18. The inhibition of NMDAR and TRPM4 coupling - a hope for novel therapeutic target for the treatment of the ischemic brain...

    Call: SONATA BIS 13 , Panel: NZ7

    Principal investigator: dr Bartosz Sebastian Pomierny

    Uniwersytet Jagielloński, Collegium Medicum

  19. Extensive analysis of the immunological profile of pediatric patients with acute lymphoblastic leukemia in order to iden...

    Call: PRELUDIUM 22 , Panel: NZ5

    Principal investigator: Anna Krętowska-Grunwald

    Uniwersytet Medyczny w Białymstoku

  20. Cuproptosis, a novel pathway of regulated cell death as a therapeutic target in treatment-naïve and targeted therapy-res...

    Call: OPUS 25 , Panel: NZ5

    Principal investigator: dr hab. Mariusz Łukasz Hartman

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  21. Molecular insights into hypoxic tumors – for development of targeted cancer therapeutics

    Call: POLONEZ BIS 3 , Panel: NZ5

    Principal investigator: dr Marco Deiana

    Politechnika Wrocławska

  22. Computational deciphering of pro-ferroptotic cell death protein machinery as a fundamental step in the search for therap...

    Call: SONATA BIS 12 , Panel: ST4

    Principal investigator: dr hab. Karolina Anna Mikulska-Rumińska

    Uniwersytet Mikołaja Kopernika, Wydział Fizyki, Astronomii i Informatyki Stosowanej

  23. Studies on the post-receptor mechanisms of TSPO in search of a novel therapeutic target of metabolic syndrome

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: dr Łukasz Kurach

    Uniwersytet Medyczny w Lublinie

  24. The role of simultaneous and individual modulation of μ-opioid, sigma-1 and histamine H3 receptors as a new therapeutic ...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: dr Katarzyna Anna Szczepańska

    Instytut Farmakologii PAN

  25. Targeting of metabolic and transcriptomic cross-talk between leukemic cells and macrophages as a therapeutic strategy in...

    Call: OPUS 22 , Panel: NZ5

    Principal investigator: dr Baran Natalia

    Instytut Hematologii i Transfuzjologii

  26. Role of RelA(p65) and cRel phosphorylations and their kinases in the biology of Diffuse-large B-cell lymphoma and Hodgki...

    Call: OPUS 22 , Panel: NZ5

    Principal investigator: dr Maciej Stefan Szydłowski

    Instytut Hematologii i Transfuzjologii

  27. Searching for new therapeutic targets in polyglutamine diseases

    Call: OPUS 22 , Panel: NZ2

    Principal investigator: prof. Marta Olejniczak

    Instytut Chemii Bioorganicznej PAN

  28. Proline metabolism as a novel therapeutic target for diseases associated with mitochondrial dysfunction.

    Call: SONATA BIS 11 , Panel: NZ3

    Principal investigator: dr Karolina Szczepanowska

    Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

  29. Toxic RNA with expanded trinucleotide repeats: pathomechanism and therapeutic targets of neurological diseases

    Call: MAESTRO 12 , Panel: NZ3

    Principal investigator: prof. Krzysztof Sobczak

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  30. The significance of circadian rhythm in urinary bladder cancer: deregulation of circadian genes as a putative therapeuti...

    Call: OPUS 19 , Panel: NZ5

    Principal investigator: prof. Edyta Wiesława Reszka

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  31. DNA polymerase θ as a novel therapeutic target in personalized anticancer therapy

    Call: OPUS 19 , Panel: NZ7

    Principal investigator: prof. Tomasz Adam Śliwiński

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  32. Screening for new therapeutic targets in inherited retinal diseases based on protein-protein interactions analysis

    Call: POLS , Panel: NZ4

    Principal investigator: dr Xiaonan Liu

    Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Medycznych w Katowicach

  33. Novel L-asparaginases as potential therapeutic agents and antimicrobial targets: structural and functional studies of en...

    Call: OPUS 19 , Panel: NZ1

    Principal investigator: prof. Mariusz Jaskólski

    Instytut Chemii Bioorganicznej PAN

  34. Understanding of the mesenchymal stem cells (MSCs)-mediated immune suppression mechanism in the neutrophilic experimenta...

    Call: PRELUDIUM 19 , Panel: NZ5

    Principal investigator: dr Marlena Tynecka

    Uniwersytet Medyczny w Białymstoku, Wydział Lekarski z Oddziałem Stomatologii i Oddziałem Nauczania w Języku Angielskim

  35. Dynamina-2 jako potencjalny cel terapeutyczny w chłoniaku rozlanym z dużych komórek B

    Call: SONATA 15 , Panel: NZ5

    Principal investigator: dr Patryk Górniak

    Instytut Hematologii i Transfuzjologii

  36. Physical exercise as a natural mechanism inducing neuroregeneration. Search for the new protein markers and therapeutic ...

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Zofia Kuter-Nowak

    Instytut Farmakologii PAN

  37. Exploring influence of inorganic cell microenvironment on NO signalling deregulation in age-related disorders. From mole...

    Call: OPUS 18 , Panel: ST4

    Principal investigator: prof. Grażyna Jolanta Stochel

    Uniwersytet Jagielloński, Wydział Chemii

  38. The 'omics' of renal cancer nucleolus: towards identification of new cancer markers and therapeutic targets.

    Call: OPUS 18 , Panel: NZ5

    Principal investigator: prof. Agnieszka Piekiełko-Witkowska

    CENTRUM MEDYCZNE KSZTAŁCENIA PODYPLOMOWEGO, Szkoła Nauk Medycznych

  39. Gankyrin protein as a new potential therapeutic target in multiple myeloma

    Call: OPUS 18 , Panel: NZ5

    Principal investigator: dr hab. Irena Misiewicz-Krzemińska

    Instytut Hematologii i Transfuzjologii

  40. The effect of Hmmr gene and its interaction with the endogenous opioid system as a novel mechanism and a therapeutic tar...

    Call: SONATA 15 , Panel: NZ5

    Principal investigator: dr Dominik Stanisław Skiba

    Instytut Genetyki i Hodowli Zwierząt PAN

  41. Oligomer-Focused Screening and Individualized Therapeutics to target Neurodegenerative Disorders

    Call: JPND2019 , Panel: NZ1

    Principal investigator: dr Piotr Hańczyc

    Uniwersytet Warszawski, Wydział Fizyki

  42. The importance of the crosstalk between alpha-synuclein and sphingosine-1-phosphate-dependent signalling in experimental...

    Call: SONATINA 3 , Panel: NZ4

    Principal investigator: dr Joanna Agata Motyl

    Instytut Biocybernetyki i Inżynierii Biomedycznej im. Macieja Nałęcza PAN

  43. Multi-level molecular assessment based on laser microdissection of corneas to reveal biomarkers and therapeutic targets ...

    Call: OPUS 16 , Panel: NZ5

    Principal investigator: prof. Marzena Magdalena Gajęcka

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

  44. Understanding the molecular basis of the regulation of activity of lysosome, a potential target of therapeutic intervent...

    Call: OPUS 14 , Panel: NZ3

    Principal investigator: prof. Magdalena Angelina Gabig-Cimińska

    Uniwersytet Gdański, Wydział Biologii

  45. CD73 (ecto-5'-nucleotidase) function in breast cancer progression and promotion, and its assessment as a therapeutic tar...

    Call: OPUS 14 , Panel: NZ5

    Principal investigator: dr hab. Patrycja Małgorzata Koszałka

    Gdański Uniwersytet Medyczny, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

  46. Peroxiredoxins as potential therapeutic targets in glioblastoma.

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: dr hab. Monika Paulina Szeliga

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  47. The role of insulin signaling in melanoma maintenance and response to targeted therapeutics

    Call: PRELUDIUM 13 , Panel: NZ3

    Principal investigator: Marta Osrodek

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  48. Identification and therapeutic use of proteasome machinery targets in human cancer

    Call: OPUS 13 , Panel: NZ5

    Principal investigator: dr Dawid Walerych

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  49. Suppression of platelet activation as a therapeutic target for patients with AERD (aspirin-exacerbated respiratory disea...

    Call: OPUS 13 , Panel: NZ5

    Principal investigator: prof. Lucyna Maria Mastalerz

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Lekarski

  50. New mulitple target-directed ligands - A1/A2A adenosine receptors antagonists and monoamine oxidase B inhibitors - searc...

    Call: PRELUDIUM 12 , Panel: NZ7

    Principal investigator: Michał Karol Załuski

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny