Search results

1. Cuproptosis, a novel pathway of regulated cell death as a therapeutic target in treatment-naïve and targeted therapy-res…

Principal investigator: dr hab. Mariusz Łukasz Hartman

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Call: OPUS 25, Panel: NZ5

2. Peroxiredoxins as potential therapeutic targets in glioblastoma.

Principal investigator: dr hab. Monika Paulina Szeliga

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: OPUS 13, Panel: NZ7

3. Targeting of metabolic and transcriptomic cross-talk between leukemic cells and macrophages as a therapeutic strategy in…

Principal investigator: dr Monika Chomczyk

Instytut Hematologii i Transfuzjologii

Call: OPUS 22, Panel: NZ5

4. Gankyrin protein as a new potential therapeutic target in multiple myeloma

Principal investigator: dr hab. Irena Misiewicz-Krzemińska

Instytut Hematologii i Transfuzjologii

Call: OPUS 18, Panel: NZ5

5. The role of insulin signaling in melanoma maintenance and response to targeted therapeutics

Principal investigator: Marta Osrodek

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Call: PRELUDIUM 13, Panel: NZ3

6. Evaluation of peroxiredoxins 1 and 2 along with the thioredoxin-thioredoxin reductase system as new therapeutic targets …

Principal investigator: dr hab. Radosław Zagożdżon

Warszawski Uniwersytet Medyczny, I Wydział Lekarski

Call: OPUS 4, Panel: NZ7

7. PIM kinases as rational therapeutic targets in lymphoid malignancies.

Principal investigator: dr hab. Przemysław Juszczyński

Instytut Hematologii i Transfuzjologii

Call: OPUS 2, Panel: NZ4

8. Cholesin and its receptor as novel therapeutic and diagnostic targets in metabolic disorders

Principal investigator: prof. Wojciech Fendler

Uniwersytet Medyczny w Łodzi

Call: OPUS 29, Panel: NZ7

9. Therapeutic potential of an FGF21 analogue in HFpEF: targeting cardiac, skeletal muscle, and cognitive function to impro…

Principal investigator: Maria Katarzyna Głowienka-Stodolak

CENTRUM MEDYCZNE KSZTAŁCENIA PODYPLOMOWEGO

Call: PRELUDIUM 24, Panel: NZ4

10. Targeted Degradation of the MLL Complex in Leukemia: A PROTAC-Based Therapeutic Strategy

Principal investigator: dr Natalia Anna Skrzypczak

Fundacja Uniwersytetu im. Adama Mickiewicza

Call: SONATINA 9, Panel: ST5

11. Identifying early biomarkers and molecular targets for therapeutic intervention in right ventricular dysfunction

Principal investigator: prof. Przemysław Błyszczuk

Uniwersytet Jagielloński

Call: OPUS 28, Panel: NZ5

12. A comprehensive structural and functional analysis of toxic RNA-protein interactions for better understanding and therap…

Principal investigator: dr hab. Agnieszka Ludmiła Kiliszek

Instytut Chemii Bioorganicznej PAN

Call: OPUS 28 (LAP), Panel: NZ5

13. The H3K27M oncohistone-centred molecular mechanisms as therapeutic targets in pediatric malignant diffuse midline glioma…

Principal investigator: dr Katarzyna Leszczyńska

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: SONATA BIS 14, Panel: NZ3

14. CD147 as a novel multifunctional modulator of podocyte metabolism and exosome biogenesis: Identification of new molecula…

Principal investigator: dr hab. Agnieszka Piwkowska

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: OPUS 27, Panel: NZ4

15. Innovative diagnostic and therapeutic strategies targeting inflammation in periodontitis.

Principal investigator: dr Maja Sochalska

Uniwersytet Jagielloński

Call: OPUS 27, Panel: NZ5

16. Modulation of protein interaction networks as a new therapeutic target in the treatment of hereditary retinal dystrophie…

Principal investigator: dr Xiaonan Liu

Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Medycznych w Katowicach

Call: SONATA 19, Panel: NZ5

17. Targeting IGH enhancer RNAs as a therapeutic approach in B-cell lymphoma

Principal investigator: dr hab. Agnieszka Dzikiewicz-Krawczyk

Instytut Genetyki Człowieka PAN

Call: SONATA BIS 13, Panel: NZ1

18. The inhibition of NMDAR and TRPM4 coupling - a hope for novel therapeutic target for the treatment of the ischemic brain…

Principal investigator: dr Bartosz Sebastian Pomierny

Uniwersytet Jagielloński, Collegium Medicum

Call: SONATA BIS 13, Panel: NZ7

19. Extensive analysis of the immunological profile of pediatric patients with acute lymphoblastic leukemia in order to iden…

Principal investigator: Anna Krętowska-Grunwald

Uniwersytet Medyczny w Białymstoku

Call: PRELUDIUM 22, Panel: NZ5

20. Molecular insights into hypoxic tumors – for development of targeted cancer therapeutics

Principal investigator: dr Marco Deiana

Politechnika Wrocławska

Call: POLONEZ BIS 3, Panel: NZ5

21. Computational deciphering of pro-ferroptotic cell death protein machinery as a fundamental step in the search for therap…

Principal investigator: dr hab. Karolina Anna Mikulska-Rumińska

Uniwersytet Mikołaja Kopernika, Wydział Fizyki, Astronomii i Informatyki Stosowanej

Call: SONATA BIS 12, Panel: ST4

22. Studies on the post-receptor mechanisms of TSPO in search of a novel therapeutic target of metabolic syndrome

Principal investigator: dr Łukasz Kurach

Uniwersytet Medyczny w Lublinie

Call: PRELUDIUM 21, Panel: NZ7

23. Targeting UDP-glucose and P2Y14 receptor interaction for therapeutic modulation of inflammatory lung diseases

Principal investigator: dr Tadeusz Piotr Karcz

Uniwersytet Jagielloński, Collegium Medicum

Call: SONATA 17, Panel: NZ7

24. Targeting of HSF1 as a therapeutic approach to inhibit the progression of hormone-dependent breast cancer.

Principal investigator: dr hab. Natalia Vydra

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Oddział w Gliwicach

Call: OPUS 22, Panel: NZ5

25. Identification and therapeutic targeting of the mRNA splicing alteration mechanisms driven by gain-of-function TP53 muta…

Principal investigator: dr Magdalena Oroń

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: SONATA 17, Panel: NZ5

26. Searching for new therapeutic targets in polyglutamine diseases

Principal investigator: prof. Marta Olejniczak

Instytut Chemii Bioorganicznej PAN

Call: OPUS 22, Panel: NZ2

27. Proline metabolism as a novel therapeutic target for diseases associated with mitochondrial dysfunction.

Principal investigator: dr Karolina Szczepanowska

Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

Call: SONATA BIS 11, Panel: NZ3

28. Toxic RNA with expanded trinucleotide repeats: pathomechanism and therapeutic targets of neurological diseases

Principal investigator: prof. Krzysztof Sobczak

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Call: MAESTRO 12, Panel: NZ3

29. The significance of circadian rhythm in urinary bladder cancer: deregulation of circadian genes as a putative therapeuti…

Principal investigator: prof. Edyta Wiesława Reszka

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Call: OPUS 19, Panel: NZ5

30. DNA polymerase θ as a novel therapeutic target in personalized anticancer therapy

Principal investigator: prof. Tomasz Adam Śliwiński

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Call: OPUS 19, Panel: NZ7

31. Screening for new therapeutic targets in inherited retinal diseases based on protein-protein interactions analysis

Principal investigator: dr Xiaonan Liu

Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Medycznych w Katowicach

Call: POLS, Panel: NZ4

32. Novel L-asparaginases as potential therapeutic agents and antimicrobial targets: structural and functional studies of en…

Principal investigator: prof. Mariusz Jaskólski

Instytut Chemii Bioorganicznej PAN

Call: OPUS 19, Panel: NZ1

33. Understanding of the mesenchymal stem cells (MSCs)-mediated immune suppression mechanism in the neutrophilic experimenta…

Principal investigator: dr Marlena Tynecka

Uniwersytet Medyczny w Białymstoku, Wydział Lekarski z Oddziałem Stomatologii i Oddziałem Nauczania w Języku Angielskim

Call: PRELUDIUM 19, Panel: NZ5

34. Physical exercise as a natural mechanism inducing neuroregeneration. Search for the new protein markers and therapeutic …

Principal investigator: dr hab. Katarzyna Zofia Kuter-Nowak

Instytut Farmakologii PAN

Call: OPUS 18, Panel: NZ7

35. Exploring influence of inorganic cell microenvironment on NO signalling deregulation in age-related disorders. From mole…

Principal investigator: prof. Grażyna Jolanta Stochel

Uniwersytet Jagielloński, Wydział Chemii

Call: OPUS 18, Panel: ST4

36. The 'omics' of renal cancer nucleolus: towards identification of new cancer markers and therapeutic targets.

Principal investigator: prof. Agnieszka Piekiełko-Witkowska

CENTRUM MEDYCZNE KSZTAŁCENIA PODYPLOMOWEGO, Szkoła Nauk Medycznych

Call: OPUS 18, Panel: NZ5

37. The effect of Hmmr gene and its interaction with the endogenous opioid system as a novel mechanism and a therapeutic tar…

Principal investigator: dr Dominik Stanisław Skiba

Instytut Genetyki i Hodowli Zwierząt PAN

Call: SONATA 15, Panel: NZ5

38. Oligomer-Focused Screening and Individualized Therapeutics to target Neurodegenerative Disorders

Principal investigator: dr Piotr Hańczyc

Uniwersytet Warszawski, Wydział Fizyki

Call: JPND2019, Panel: NZ1

39. The importance of the crosstalk between alpha-synuclein and sphingosine-1-phosphate-dependent signalling in experimental…

Principal investigator: dr Joanna Agata Motyl

Instytut Biocybernetyki i Inżynierii Biomedycznej im. Macieja Nałęcza PAN

Call: SONATINA 3, Panel: NZ4

40. Multi-level molecular assessment based on laser microdissection of corneas to reveal biomarkers and therapeutic targets …

Principal investigator: prof. Marzena Magdalena Gajęcka

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

Call: OPUS 16, Panel: NZ5

41. Understanding the molecular basis of the regulation of activity of lysosome, a potential target of therapeutic intervent…

Principal investigator: prof. Magdalena Angelina Gabig-Cimińska

Uniwersytet Gdański, Wydział Biologii

Call: OPUS 14, Panel: NZ3

42. CD73 (ecto-5'-nucleotidase) function in breast cancer progression and promotion, and its assessment as a therapeutic tar…

Principal investigator: dr hab. Patrycja Małgorzata Koszałka

Gdański Uniwersytet Medyczny, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

Call: OPUS 14, Panel: NZ5

43. Identification and therapeutic use of proteasome machinery targets in human cancer

Principal investigator: dr Dawid Walerych

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: OPUS 13, Panel: NZ5

44. Suppression of platelet activation as a therapeutic target for patients with AERD (aspirin-exacerbated respiratory disea…

Principal investigator: prof. Lucyna Maria Mastalerz

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Lekarski

Call: OPUS 13, Panel: NZ5

45. New mulitple target-directed ligands - A1/A2A adenosine receptors antagonists and monoamine oxidase B inhibitors - searc…

Principal investigator: Michał Karol Załuski

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: PRELUDIUM 12, Panel: NZ7

46. Modeling of structure of gamma-aminobutyric acid transporters as an essential biological and therapeutic target

Principal investigator: dr hab. Marek Wojciech Bajda

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: SONATA 12, Panel: NZ7

47. Analysis of somatic mutations in miRNA and miRNA-biogenesis genes to identify new therapeutic targets and biomarkers of …

Principal investigator: prof. Piotr Kozłowski

Instytut Chemii Bioorganicznej PAN

Call: MAESTRO 8, Panel: NZ2

48. Modulation of fatty acid binding protein 4 and dietary fatty acid intake as a potential therapeutic target in the manage…

Principal investigator: Paula Mosińska

Uniwersytet Medyczny w Łodzi, Wydzial Lekarski

Call: PRELUDIUM 11, Panel: NZ5

49. Research on human eosinophils as a potential therapeutic target.

Principal investigator: Marek Rafał Grosicki

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: PRELUDIUM 7, Panel: NZ7

50. Analysis of relations on the level of metabolome, miRNome, and transcriptome of human renal cancer: towards identificati…

Principal investigator: dr hab. Agnieszka Piekiełko-Witkowska

CENTRUM MEDYCZNE KSZTAŁCENIA PODYPLOMOWEGO

Call: OPUS 7, Panel: NZ5

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