Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Gankyrin protein as a new potential therapeutic target in multiple myeloma

2019/35/B/NZ5/02824

Keywords:

multiple myeloma proteins gankyrin biomarkers drug resistance terapeutic target CRISPR RNAi transcriptome

Descriptors:

  • NZ5_003:

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Instytut Hematologii i Transfuzjologii

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Irena Misiewicz-Krzemińska 

Number of co-investigators in the project: 7

Call: OPUS 18 - announced on 2019-09-16

Amount awarded: 3 221 640 PLN

Project start date (Y-m-d): 2020-10-05

Project end date (Y-m-d): 2025-10-04

Project duration:: 60 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (3)
  1. Expression of p53 protein isoforms predicts survival in patients with multiple myeloma
    Authors:
    Rojas EA, Corchete LA, De Ramón C, Krzeminski P, Quwaider D, García-Sanz R, Martínez-López J, Oriol A, Rosiñol L, Bladé J, Lahuerta JJ, San Miguel JF, González M, Mateos MV, Bourdon JC, Misiewicz-Krzeminska I, Gutiérrez NC.
    Academic press:
    American Journal of Hematology (rok: 2022, tom: 97(6), strony: 700-710), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/ajh.26507 - link to the publication
  2. Extracellular Vesicles in Multiple Myeloma-Cracking the Code to a Better Understanding of the Disease
    Authors:
    Iskrzak J, Zygmunciak P, Misiewicz-Krzemińska I, Puła B.
    Academic press:
    Cancers (rok: 2022, tom: 14(22), strony: 5575), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers14225575 - link to the publication
  3. Factors determining the sensitivity to proteasome inhibitors of multiple myeloma cells
    Authors:
    Marta Pelon, Patryk Krzeminski, Zuzanna Tracz-Gaszewska, Irena Misiewicz-Krzeminska
    Academic press:
    Frontiers in Pharmacology (rok: 2024, tom: 15, strony: 1351565), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fphar.2024.1351565 - link to the publication

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