Projects funded by the NCN


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60 projects found matching your search criteria :

  1. Unlocking longevity: galectins from the unique naked mole rat as a potential anti-aging agents for biomedical applicatio...

    Call: PRELUDIUM 24 , Panel: NZ3

    Principal investigator: Julia Wiktoria Ptak

    Uniwersytet Wrocławski

  2. Targeting endothelial cell senescence in diabetic retinopathy with rapamycin-loaded nanoparticles

    Call: PRELUDIUM 24 , Panel: NZ7

    Principal investigator: Gabriela Burda

    Uniwersytet Jagielloński

  3. Could fibroblast senescence and their resistance to apoptosis be the hidden drivers behind endometrial fibrosis in equin...

    Call: OPUS 28 , Panel: NZ5

    Principal investigator: dr Katarzyna Karolina Piotrowska-Tomala

    Instytut Rozrodu Zwierząt i Badań Żywności PAN

  4. Development of novel potential therapeutics in inflammatory bowel diseases based on nanoformulations employing senomodul...

    Call: OPUS 27 , Panel: NZ7

    Principal investigator: prof. Jakub Jerzy Fichna

    Uniwersytet Medyczny w Łodzi

  5. Cellular senescence as a new mechanism in development and progression of head and neck cancer

    Call: OPUS 26 , Panel: NZ5

    Principal investigator: prof. Michał Mateusz Masternak

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  6. Spermidine Regulates Dark-Induced Leaf Senescence: eukaryotic translation factor 5A -Dependent and Independent Manner

    Call: SONATA 19 , Panel: NZ9

    Principal investigator: dr Ewelina Dagmara Paluch-Lubawa

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  7. Targeting mitochondrial potassium channels to regulate cellular senescence.

    Call: OPUS 26 , Panel: NZ5

    Principal investigator: prof. Adam Michał Szewczyk

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  8. Amorphous Senolytics: A Breakthrough Approach in Senescence Modulation and Age-Related Disease Treatment

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Szymon Sip

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

  9. The influence of NF kappa beta-dependent inflammation induced by oxidative stress on cellular senescence in obstructive ...

    Call: PRELUDIUM 22 , Panel: NZ5

    Principal investigator: Szymon Jan Turkiewicz

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  10. Senolytic nanoplatform to target and eliminate skin cancer Zombie cells

    Call: M-ERA.NET 2022 , Panel: ST5

    Principal investigator: dr hab. Anna Karolina Lewińska

    Uniwersytet Rzeszowski, Kolegium Nauk Przyrodniczych

  11. Investigation of senescence-associated alterations in the nuclear protein complex (NPC) composition and nuclear transpor...

    Call: OPUS 23 , Panel: NZ5

    Principal investigator: dr hab. Anna Bielak-Żmijewska

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  12. N6-methyladenosine (m6A) RNA modification as a putative metabolic switch between cell survival and cell death in induced...

    Call: PRELUDIUM 21 , Panel: NZ9

    Principal investigator: Elżbieta Marta Rudy

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  13. OXPHOS dynamics in cellular senescence

    Call: SONATINA 6 , Panel: NZ1

    Principal investigator: dr Hanna Małgorzata Salmonowicz

    Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

  14. Electrospun nanofiber-based nanoplatform for delivery of new nutraceutical derivatives to eliminate chemotherapy-induced...

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: dr hab. Maciej Antoni Wnuk

    Uniwersytet Rzeszowski, Collegium Medicum

  15. In search for novel markers of senescence and causes of senescent cells accumulation in atherosclerotic plaque

    Call: OPUS 22 , Panel: NZ5

    Principal investigator: dr hab. Agnieszka Anna Jaźwa-Kusior

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  16. In vitro tracing of cellular senescence to cancer stem cell formation using a nanoparticle-based reporter system

    Call: OPUS 22 , Panel: NZ3

    Principal investigator: dr Patrick McDevitt Perrigue

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Centrum NanoBioMedyczne

  17. Reversible senescence as a new mechanism of cancer cell resistance for chemotherapy. Analysis of the mechanism of cancer...

    Call: SONATINA 5 , Panel: NZ3

    Principal investigator: dr Karolina Anna Staniak

    Politechnika Warszawska, Wydział Chemiczny

  18. Novel hybrid antioxidants containing nitroxyl and phenolic functional group - investigations in chemical and biological ...

    Call: PRELUDIUM 19 , Panel: ST4

    Principal investigator: Adrian Konopko

    Uniwersytet Warszawski, Wydział Chemii

  19. Application of small compounds in the epigenetic therapy of malignant brain gliomas

    Call: OPUS 19 , Panel: NZ5

    Principal investigator: prof. Mirosława Zofia Naskręt-Barciszewska

    Instytut Chemii Bioorganicznej PAN

  20. Exosome-dependent pathomechanism of dormant ovarian cancer cell awakening and growth reinforcement by normal peritoneal ...

    Call: OPUS 19 , Panel: NZ5

    Principal investigator: prof. Krzysztof Stefan Książek

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Medyczny

  21. Targeting senescent brain cells to improve cognitive function in animal models of ageing and depression

    Call: OPUS 18 , Panel: NZ4

    Principal investigator: prof. Ewa Zofia Sikora

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  22. Protein S-nitrosation as a trigger for DNA leakage from the nucleus: in the quest for a mechanism

    Call: PRELUDIUM 18 , Panel: NZ3

    Principal investigator: Aleksandra Anna Kopacz

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  23. How to keep lipids in the leves? Deciphering the interplay between lipid storage and degradation during leaf senescence.

    Call: SONATA BIS 9 , Panel: NZ1

    Principal investigator: dr hab. Agnieszka Zienkiewicz

    Uniwersytet Mikołaja Kopernika, Interdyscyplinarne Centrum Nowoczesnych Technologii

  24. The impact of synovial fluid microenvironment onto the viability, differentiation and senescence of chondrogenic progeni...

    Call: OPUS 17 , Panel: NZ5

    Principal investigator: dr hab. Tomasz Wiktor Trzeciak

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  25. The role of autophagy in the regulation of secretion of extracellular vesicles and proteins at different stages of vascu...

    Call: OPUS 16 , Panel: NZ3

    Principal investigator: dr hab. Grażyna Krystyna Mosieniak

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  26. Fibrosis or senescence- why transcriptionally inactivity of Nrf2 protects against colon dysfunction

    Call: SONATA 14 , Panel: NZ4

    Principal investigator: dr Aleksandra Barbara Piechota-Polańczyk

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  27. Epigenetic dissection of induced barley leaf senescence and its utilization in crop improvement.

    Call: SONATA BIS 8 , Panel: NZ9

    Principal investigator: dr hab. Ewa Anna Sobieszczuk-Nowicka

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  28. Epithelial-to-mesenchymal transition of human peritoneal mesothelial cells undergoing senescence

    Call: PRELUDIUM 15 , Panel: NZ3

    Principal investigator: dr Edyta Kawka

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Medyczny

  29. Polyamines - a new metabolic switch for barley leaf senesence: developing molecular basis of the network regulation of t...

    Call: OPUS 15 , Panel: NZ9

    Principal investigator: dr hab. Ewa Anna Sobieszczuk-Nowicka

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  30. Reprograming of leaves senescence by polyamines - new perspectives to enhance crop plants stress tolerance

    Call: PRELUDIUM 14 , Panel: NZ9

    Principal investigator: Ewelina Dagmara Paluch-Lubawa

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  31. Role of autophagy and mitochondrial quality control mechanisms in the protective action of PGC-1alpha against oxidative ...

    Call: OPUS 14 , Panel: NZ3

    Principal investigator: prof. Janusz Błasiak

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  32. SnRK2 protein kinases as integrators of environmental signals in the regulation of the senescence in plants

    Call: OPUS 14 , Panel: NZ3

    Principal investigator: dr Anna Marta Kulik

    Instytut Biochemii i Biofizyki PAN

  33. Role of autophagy and senescence in cancer chemoresistance: in vitro studies, in vivo studies, and analysis of clinical ...

    Call: SONATA BIS 7 , Panel: NZ3

    Principal investigator: dr Halina Maria Waś

    Wojskowy Instytut Medyczny

  34. Nitroxyl as an alternative or competitive to nitric oxide metabolic link in plants in the model Arabidopsis thaliana

    Call: SONATA BIS 7 , Panel: NZ4

    Principal investigator: dr hab. Magdalena Arasimowicz-Jelonek

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  35. The role of tumor secretable factors in modulation of endothelial senescence cells activity

    Call: SONATA 13 , Panel: NZ7

    Principal investigator: dr Wojciech Michał Ciszewski

    Uniwersytet Medyczny w Łodzi, Wydział Nauk o Zdrowiu

  36. Spontaneous senescence of ovarian cancer cells as an underestimated determinant of tumor progression: research on in vit...

    Call: OPUS 13 , Panel: NZ3

    Principal investigator: prof. Krzysztof Stefan Książek

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Medyczny

  37. The mechanisms that regulate woody plant organ senescence

    Call: PRELUDIUM 12 , Panel: NZ3

    Principal investigator: Natalia Wojciechowska

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  38. Molecular identification of signalling pathways activated by receptor kinase CRK5 during senescence and stress response ...

    Call: SONATA 12 , Panel: NZ1

    Principal investigator: dr Paweł Burdiak

    Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Instytut Biologii

  39. Senescence or apoptosis: role of miR-34a in endothelial cells

    Call: SONATA BIS 6 , Panel: NZ3

    Principal investigator: dr Anna Grochot-Przęczek

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  40. Histone demethylase JMJD3 as an epigenetic regulator in the senescence-associated secretory phenotype and cancer

    Call: SONATA 11 , Panel: NZ3

    Principal investigator: dr Patrick McDevitt Perrigue

    Instytut Chemii Bioorganicznej PAN

  41. Epigenetic changes leading to remodeling of chromatin structure and alterations in gene expression in replicative and pr...

    Call: OPUS 11 , Panel: NZ3

    Principal investigator: dr hab. Anna Bielak-Żmijewska

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  42. Mitotic catastrophe and amplicon loss as a basis of negative selection of glioblastoma cells with oncogene amplicons

    Call: SONATA 11 , Panel: NZ3

    Principal investigator: dr hab. Ewelina Stoczyńska-Fidelus

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski; Oddział Nauk Biomedycznych

  43. AP-1 : a novel player in the regulation of Senescence Associated Secretory Phenotype of cancer cells

    Call: PRELUDIUM 10 , Panel: NZ3

    Principal investigator: Anna Aneta Strzeszewska

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  44. A role of IQGAP1 in the formation of cytoplasmic bridges involved in the direct intercellular protein transfer between s...

    Call: PRELUDIUM 9 , Panel: NZ3

    Principal investigator: Wioleta Małgorzata Grabowska

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  45. The significance of cell senescence and polyploidy in the life cycle of cancer;in vitro studies

    Call: OPUS 9 , Panel: NZ3

    Principal investigator: prof. Ewa Zofia Sikora

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  46. Senescence changes in key vitality-related metabolic systems of the newly discovered Apis mellifera worker sub-caste; re...

    Call: OPUS 8 , Panel: NZ9

    Principal investigator: dr hab. Aneta Joanna Strachecka

    Uniwersytet Przyrodniczy w Lublinie, Wydział Biologii, Nauk o Zwierzętach i Biogospodarki

  47. A protective action of cytokinins on the photosynthetic electron transport

    Call: PRELUDIUM 8 , Panel: NZ9

    Principal investigator: Ernest Skowron

    Uniwersytet Jana Kochanowskiego w Kielcach, Wydział Matematyczno-Przyrodniczy

  48. The role of the factors secreted by senescent vascular smooth muscle cells in the modulation in the functioning of the i...

    Call: OPUS 8 , Panel: NZ3

    Principal investigator: dr Grażyna Krystyna Mosieniak

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  49. Effect of peritoneal mesothelium senescence on the functionality of intercellular junctions and the inducibility of epit...

    Call: OPUS 8 , Panel: NZ3

    Principal investigator: prof. Krzysztof Stefan Książek

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski II

  50. Programmed cell death as an essential process during plant organ growth and senescence on the example of model species P...

    Call: SONATA BIS 2 , Panel: NZ9

    Principal investigator: dr hab. Agnieszka Maria Bagniewska-Zadworna

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii