Exosome-dependent pathomechanism of dormant ovarian cancer cell awakening and gr

Exosome-dependent pathomechanism of dormant ovarian cancer cell awakening and growth reinforcement by normal peritoneal cells subjected to carboplatin and paclitaxel

2020/37/B/NZ5/00100

Keywords

Descriptors

NZ5_003: Patogeneza chorób człowieka
NZ5_001: Etiologia chorób człowieka
NZ3_004: Starzenie

Panel

NZ5 – Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Medyczny

Voivodeship: wielkopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

prof. Justyna Stefan Mikuła-Pietrasik

Number of co-investigators in the project: 10

Call

OPUS 19 – announced on 2020-03-16

Amount awarded: 2 199 120 PLN
Project start date: 2021-06-01
Project end date: 2025-12-31
Project duration: 55 months (the same as in the proposal)
Project status: Project completed

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (2)

Serum starvation-based method of ovarian cancer cell dormancy induction and termination in vitro

Authors:
Rutecki S, Leśniewska-Bocianowska A, Chmielewska K, Matuszewska J, Naumowicz E, Uruski P, Radziemski A, Mikuła-Pietrasik J, Tykarski A, Książek K.

Academic press:
Biology Methods & Protocols (year: 2023, volume: 8(1), pages: bpad029), Publisher: Oxford University Press

Status:
Published

DOI:
10.1093/biomethods/bpad029. – link to the publication
Mechanisms of carboplatin- and paclitaxel-dependent induction of premature senescence and pro-cancerogenic conversion of normal peritoneal mesothelium and fibroblasts

Authors:
Rutecki S, Pakuła-Iwańska M, Leśniewska-Bocianowska A, Matuszewska J, Rychlewski D, Uruski P, Stryczyński Ł, Naumowicz E, Szubert S, Tykarski A, Mikuła-Pietrasik J, Książek K.

Academic press:
Journal of Pathology (year: 2024, volume: 262, pages: 198-211), Publisher: Wiley

Status:
Published

DOI:
10.1002/path.6223. – link to the publication

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