Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Role of autophagy and senescence in cancer chemoresistance: in vitro studies, in vivo studies, and analysis of clinical samples

2017/26/E/NZ3/00434

Keywords:

cancer chemotherapy autophagy metabolism hypoxia angiogenesis

Descriptors:

  • NZ3_8:
  • NZ3_4:
  • NZ3_1:

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Wojskowy Instytut Medyczny

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Halina Maria Waś 

Number of co-investigators in the project: 4

Call: SONATA BIS 7 - announced on 2017-06-14

Amount awarded: 2 925 000 PLN

Project start date (Y-m-d): 2018-10-02

Project end date (Y-m-d): 2024-03-01

Project duration:: 65 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (9)
  1. Escape from cisplatin-induced senescence of hypoxic lung cancer cells can be overcome by hydroxychloroquine
    Authors:
    Aleksandra Olszewska, Agata Borkowska, Monika Granica, Justyna Karolczak, Bartosz Zglinicki, Claudine Kieda and Halina Was
    Academic press:
    Frontiers in Oncology (rok: 2022, tom: 11, strony: 738385), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fonc.2021.738385 - link to the publication
  2. Polyploidy formation in cancer cells: how a Trojan horse is born
    Authors:
    Halina Was, Agata Borkowska, Aleksandra Olszewska, Aleksandra Klemba, Marta Marciniak, Agnieszka Synowiec, Claudine Kieda
    Academic press:
    Seminars in Cancer Biology (rok: 2022, tom: 81, strony: 24-36), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.semcancer.2021.03.003 - link to the publication
  3. Mechanisms of chemotherapy-induced neurotoxicity
    Authors:
    Halina Was, Agata Borkowska, Ana Bagues, Longlong Tu, Julia YH Liu, Zengbing Lu, John A Rudd, Kulmira Nurgali and Raquel Abalo
    Academic press:
    Frontiers in Pharmacology (rok: 2022, tom: 13, strony: 750507), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fphar.2022.750507 - link to the publication
  4. Mechanisms of chemotherapy-induced neurotoxicity
    Authors:
    Halina Was, Agata Borkowska, Ana Bagues, Longlong Tu, Julia YH Liu, Zengbing Lu, John A Rudd, Kulmira Nurgali and Raquel Abalo
    Academic press:
    Frontiers in Pharmacology (rok: 2022, tom: 13, strony: 750507), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fphar.2022.750507 - link to the publication
  5. Risk factors of using late-autophagy inhibitors: aspects to consider when combined with anticancer therapies
    Authors:
    Maciej Skrzeszewski, Monika Maciejewska, Dagmara Kobza, Aleksandra Gawrylak, Claudine Kieda1, and Halina Waś
    Academic press:
    Biochemical Pharmacology (rok: 2024, tom: 225, strony: 116277), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bcp.2024.116277 - link to the publication
  6. Escape from cisplatin-induced senescence of hypoxic lung cancer cells can be overcome by hydroxychloroquine
    Authors:
    Aleksandra Olszewska, Agata Borkowska, Monika Granica, Justyna Karolczak, Bartosz Zglinicki, Claudine Kieda and Halina Was
    Academic press:
    Frontiers in Oncology (rok: 2022, tom: 11, strony: 738385), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fonc.2021.738385 - link to the publication
  7. High Hemin Concentration Induces Escape from Senescence of Normoxic and Hypoxic Colon Cancer Cells
    Authors:
    Agata Borkowska, Aleksandra Olszewska, Weronika Skarzynska, Marta Marciniak, Maciej Skrzeszewski, Claudine Kieda and Halina Was
    Academic press:
    Cancers (rok: 2022, tom: 14, strony: 194793), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers14194793 - link to the publication
  8. Risk factors of using late-autophagy inhibitors: aspects to consider when combined with anticancer therapies
    Authors:
    Maciej Skrzeszewski, Monika Maciejewska, Dagmara Kobza, Aleksandra Gawrylak, Claudine Kieda1, and Halina Waś
    Academic press:
    Biochemical Pharmacology (rok: 2024, tom: 225, strony: 116277), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bcp.2024.116277 - link to the publication
  9. Polyploidy formation in cancer cells: how a Trojan horse is born
    Authors:
    Halina Was, Agata Borkowska, Aleksandra Olszewska, Aleksandra Klemba, Marta Marciniak, Agnieszka Synowiec, Claudine Kieda
    Academic press:
    Seminars in Cancer Biology (rok: 2022, tom: 81, strony: 24-36), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.semcancer.2021.03.003 - link to the publication

O Narodowym Centrum Nauki

Finansowanie nauki

Współpraca zagraniczna

Centrum prasowe

Deklaracja dostępności
Przetwarzanie danych osobowych
Polityka cookies

Partnerzy