Search results

51. The role of urokinase-type plasminogen activator receptor in the process of endothelial microparticle formation and inte…

Principal investigator: Martyna Maria Durak-Kozica

Uniwersytet Jagielloński, Wydział Fizyki, Astronomii i Informatyki Stosowanej

Call: PRELUDIUM 8, Panel: NZ5

52. The influence of 5-HT7 and NMDA receptor ligands with possible antidepressive properties on the activity of rat dorsal r…

Principal investigator: prof. Grzegorz Władysław Hess

Instytut Farmakologii PAN

Call: OPUS 6, Panel: NZ4

53. Mycobacterium species and strains with varying cell wall composition: role of pattern recognition receptors in activatio…

Principal investigator: Iwona Karwaciak

Instytut Biologii Medycznej PAN

Call: PRELUDIUM 6, Panel: NZ6

54. Regulation of expression and role of peroxisome proliferator-activated receptors (PPARs) during conceptus implantation a…

Principal investigator: dr hab. Agnieszka Blitek

Instytut Rozrodu Zwierząt i Badań Żywności PAN

Call: OPUS 6, Panel: NZ9

55. The influence of glucagon-like peptied-1 receptor agaonists on regulation of coticotropin-releasing hormone gene promote…

Principal investigator: Jan Stanisław Detka

Instytut Farmakologii PAN

Call: PRELUDIUM 4, Panel: NZ7

56. Influence of PPAR-gama receptor agonists on antitumor activity of photodynamic therapy.

Principal investigator: dr Piotr Marek Mrówka

Warszawski Uniwersytet Medyczny, Wydział Nauki o Zdrowiu

Call: PRELUDIUM 3, Panel: NZ5

57. Physiological and toxicological aspects of the aryl hydrocarbon receptor (AhR) activation in the regulation of granulosa…

Principal investigator: prof. Renata Elżbieta Ciereszko

Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Biologii i Biotechnologii

Call: OPUS 3, Panel: NZ9

58. Novel multi-target directed ligands combining cholinesterase inhibition and 5-HT6 antagonism - design, synthesis and pha…

Principal investigator: dr hab. Anna Karolina Więckowska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: SONATA 12, Panel: NZ7

59. Molecular identification of signalling pathways activated by receptor kinase CRK5 during senescence and stress response …

Principal investigator: dr Paweł Burdiak

Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Instytut Biologii

Call: SONATA 12, Panel: NZ1

60. Synthesis and pharmacological properties of mono- di- and triheterocyclic azole derivatives as a hybrid receptor and PDE…

Principal investigator: prof. Maciej Henryk Pawłowski

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: OPUS 4, Panel: NZ7

61. Does DREADD and TrkB gene transfer targeted to selected motoneurons following spinal cord injury bring recovery of motor…

Principal investigator: prof. Małgorzata Hanna Skup

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: OPUS 16, Panel: NZ4

62. Selective inhibition of NMDAR activity during epileptogenesis as a therapeutic approach to cure epilepsy

Principal investigator: dr Adam Gorlewicz

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: SONATA 10, Panel: NZ7

63. Anilide derivatives of long-chain cyclic amines as multifunctional serotonin receptors ligands and phosphodiesterase 7 i…

Principal investigator: dr Agnieszka Wioleta Jankowska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: PRELUDIUM 13, Panel: NZ7

64. The mechanism of ligand binding and the conformational changes in the beta2-adrenergic receptor molecule

Principal investigator: dr Anita Płazińska

Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny z Oddziałem Analityki Medycznej

Call: SONATA 5, Panel: NZ2

65. Dopaminergic modulation of high frequency oscillations in the rat olfactory bulb associated with the NMDA receptor hypof…

Principal investigator: Jacek Wróbel

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: PRELUDIUM 20, Panel: NZ4

66. Therapeutic potential of biased 5-HT7 receptor ligands in the treatment of depression

Principal investigator: prof. Paweł Maria Zajdel

Uniwersytet Jagielloński, Collegium Medicum

Call: OPUS 17, Panel: NZ7

67. Design and Pharmacological Evaluation of Marine Alkaloid-Inspired 5-HT2A Receptor Ligands

Principal investigator: Szymon Kazimierz Kordylewski

Instytut Farmakologii PAN

Call: PRELUDIUM 24, Panel: NZ1

68. Neuroprotective properties of 5-HT6 receptor ligands in the group of 2-arylpyrrole derivatives – a new insight into neur…

Principal investigator: Marcin Józef Drop

Uniwersytet Jagielloński, Collegium Medicum

Call: PRELUDIUM 17, Panel: NZ7

69. Conjugated linoleic acid (CLA)-induced transcriptional activation of PPAR-an investigation of molecular machanisms of pu…

Principal investigator: prof. Teresa Leszczyńska

Uniwersytet Rolniczy im. Hugona Kołłątaja w Krakowie, Wydział Technologii Żywności

Call: OPUS 2, Panel: NZ9

70. Unraveling protease activation in stimulated CAR-T cells to identify new biomarkers for assessing their clinical efficac…

Principal investigator: dr hab. Małgorzata Firczuk

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: OPUS 25, Panel: NZ7

71. Studies on regulation of biosynthesis and on proinflammatory activity of the peptide bacteriocin BaSp222

Principal investigator: dr hab. Paweł Mak

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Call: OPUS 16, Panel: NZ3

72. Tetrabromobisphenol A (TBBPA), the most widely used compound among brominated flame retardants, as the active endocrine …

Principal investigator: Ewelina Barbara Honkisz

Uniwersytet Rolniczy im. Hugona Kołłątaja w Krakowie, Wydział Hodowli i Biologii Zwierząt

Call: PRELUDIUM 1, Panel: NZ4

73. GLP-1R activation as an approach to modulate the effects of HHV-1 on neuronal functions – studies in mouse astrocytes

Principal investigator: Adrianna Niedzielska

Szkoła Główna Gospodarstwa Wiejskiego w Warszawie

Call: PRELUDIUM 24, Panel: NZ5

74. Personalized selective activation of γδT Vδ2 cells using zoledronic acid for glioblastoma MICA/Bhigh therapy: in vitro a…

Principal investigator: Natalia Anna Lehman

Uniwersytet Medyczny w Lublinie

Call: PRELUDIUM 24, Panel: NZ4

75. Actin cytoskeleton disorders as a pro-survival signaling activator and a therapeutic biomarker in Diffuse Large B-cell L…

Principal investigator: dr Patryk Górniak

Instytut Hematologii i Transfuzjologii

Call: SONATA BIS 13, Panel: NZ5

76. Novel broad-spectrum central nervous system active substances: optimization of their multi-target profile

Principal investigator: dr hab. Agnieszka Anna Kaczor

Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny

Call: OPUS 22, Panel: NZ7

77. Parallel quantitative evaluation of targetability, cellular uptake, and intracellular drug release for the establishment…

Principal investigator: prof. Adolfo Rivero Müller

Uniwersytet Medyczny w Lublinie, Wydział Nauk Medycznych

Call: OPUS 20 (LAP), Panel: ST5

78. New derivatives of clopidogrel - enantioselective biosynthesis and antiplatelet activity in vitro

Principal investigator: Adam Edward Sikora

Uniwersytet Mikołaja Kopernika w Toruniu, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy; Wydział Farmaceutyczny

Call: PRELUDIUM 14, Panel: NZ7

79. The role of brain glutamatergic system in the neuroendocrine regulation of cytochrome P450 expression and activity in th…

Principal investigator: prof. Władysława Anna Daniel

Instytut Farmakologii PAN

Call: OPUS 12, Panel: NZ7

80. The role of (R,S)-Sulforaphane-induced activation of Nrf2 transcription factor in the regulation of depressive-like beha…

Principal investigator: dr Patrycja Anna Pańczyszyn-Trzewik

Uniwersytet Rzeszowski, Kolegium Nauk Medycznych

Call: PRELUDIUM 12, Panel: NZ4

81. Mechanism and significance of HSF1 activation in estrogen-induced neoplastic transformation.

Principal investigator: dr Natalia Vydra

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Oddział w Gliwicach

Call: OPUS 7, Panel: NZ7

82. Synbiotics-activated TLR-signaling as a measure of improved immunity in chickens

Principal investigator: dr Anna Sławińska

Uniwersytet Technologiczno-Przyrodniczy im. Jana i Jędrzeja Śniadeckich w Bydgoszczy, Wydział Hodowli i Biologii Zwierząt

Call: OPUS 6, Panel: NZ9

83. Nectin-3 cleavage under neuronal activation.

Principal investigator: dr Emilia Rejmak-Kozicka

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: PRELUDIUM 5, Panel: NZ3

84. Purinergic modification of glomerular barrier permeability for proteins during short-time activation of renin-angiotensi…

Principal investigator: Małgorzata Kasztan

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

Call: PRELUDIUM 3, Panel: NZ4

85. Chemical synthesis of 1-O-acyl-2-O-methyl-3-O-phosphodiester and 1-O-acyl-2-O-methyl-3-O-phosphorothioate analogs of sel…

Principal investigator: prof. Andrzej Okruszek

Politechnika Łódzka, Wydział Biotechnologii i Nauk o Żywności

Call: OPUS 1, Panel: ST5

86. Brain regions that mediate antipsychotic-induced changes in oscillatory activity recorded in the nucleus accumbens

Principal investigator: dr Mark Jeremy Hunt

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: OPUS 2, Panel: NZ4

87. NMR Spectroscopy as Molecular Language: A Deep Learning Approach to Bioactivity Prediction

Principal investigator: Arkadiusz Bogumił Leniak

Instytut Farmakologii PAN

Call: PRELUDIUM 24, Panel: NZ7

88. Study of the hormonal and molecular mechanisms of tumorigenesis in the interstitial tissue of the male gonad

Principal investigator: prof. Barbara Bilińska

Uniwersytet Jagielloński, Wydział Biologii

Call: OPUS 12, Panel: NZ4

89. The mechanism of neurotoxic action of benzophenone-3

Principal investigator: prof. Bogusława Budziszewska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: OPUS 8, Panel: NZ7

90. A new concept of inhibiting the progression of Alzheimer's disease based on the modification of the blood-brain barrier …

Principal investigator: prof. Agnieszka Basta-Kaim

Instytut Farmakologii PAN

Call: OPUS 28, Panel: NZ4

91. Application of bioconjugation strategy to the synthesis of anticancer Trojan horses

Principal investigator: dr hab. Michał Piotr Antoszczak

Uniwersytet im. Adama Mickiewicza w Poznaniu

Call: OPUS 28, Panel: ST5

92. Zn2+-dependent competition between CD4 and CD8α coreceprtor for Lck tyrosine kinase

Principal investigator: dr Anna Marta Kocyła

Uniwersytet Wrocławski, Wydział Biotechnologii

Call: SONATA 19, Panel: NZ1

93. Protease-induced neutrophilic networks in cancer development.

Principal investigator: dr Danuta Teresa Bryzek

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Call: SONATA 19, Panel: NZ5

94. Assessing protein-ligand complexes with ML/DL models trained on molecular dynamics-based descriptors.

Principal investigator: dr hab. Paweł Aleksander Siedlecki

Instytut Biochemii i Biofizyki PAN

Call: OPUS 20, Panel: ST4

95. FAST interactions in cell death regulation

Principal investigator: Daria Martyna Dawidziak

Uniwersytet Warszawski, Wydział Chemii

Call: PRELUDIUM 19, Panel: NZ1

96. Anticancer Trojan horses: Application of the bioconjugation idea to invent new anticancer drugs

Principal investigator: dr Michał Piotr Antoszczak

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

Call: UWERTURA 3, Panel: ST4

97. Effect of experimentally-induced inflammatory process of uterus on its innervation and role of neurotransmitters in the …

Principal investigator: prof. Barbara Jana

Instytut Rozrodu Zwierząt i Badań Żywności PAN

Call: OPUS 8, Panel: NZ5

98. Mitochondrial metabolism of glycerol as a regulator of lymphocyte homeostasis and pathology

Principal investigator: dr Marcin Kaminski

Politechnika Śląska

Call: OPUS 27, Panel: NZ6

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