Projects funded by the NCN

Novel L-asparaginases as potential therapeutic agents and antimicrobial targets: structural and functional studies of en...

Call: OPUS 19 , Panel: NZ1

Principal investigator: prof. Mariusz Jaskólski

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Inhalable polymeric delivery systems of antibiotics and quorum sensing inhibitors for the treatment of respiratory infec...

Call: OPUS 18 , Panel: ST5

Principal investigator: prof. Elżbieta Pamuła

Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie, Wydział Inżynierii Materiałowej i Ceramiki

Molecular mechanisms, signal transduction and inhibition of PEBP1-15LOX protein complex triggering the ferroptotic cell ...

Call: SONATA 15 , Panel: ST4

Principal investigator: dr hab. Karolina Anna Mikulska-Rumińska

Uniwersytet Mikołaja Kopernika w Toruniu, Wydział Fizyki, Astronomii i Informatyki Stosowanej

Novel, rationally designed modulators of glycosomal import of enzymes in Trypanosoma parasites

Call: OPUS 16 , Panel: NZ7

Principal investigator: prof. Maciej Filip Dawidowski

Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny

Gold and silver nanoparticles as carriers for delivery of 5' end mRNA cap analogues with potential therapeutical applica...

Call: OPUS 16 , Panel: ST5

Principal investigator: dr hab. Marzena Jankowska-Anyszka

Uniwersytet Warszawski, Wydział Chemii

Histidine Biosynthetic Pathway in Plants: Structural and Functional Studies as a Framework for the Design of Inhibitors ...

Call: SONATA 14 , Panel: NZ1

Principal investigator: dr hab. Miłosz Ruszkowski

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Search for structure-antimicrobial activity correlation for selected boraheterocycles

Call: OPUS 16 , Panel: ST5

Principal investigator: prof. Sergiusz Mariusz Luliński

Politechnika Warszawska, Wydział Chemiczny

De novo designed, structurally extended peptide foldamers and their use for construction of PD-1/PD-L1 interaction inhib...

Call: OPUS 16 , Panel: ST5

Principal investigator: dr hab. Łukasz Berlicki

Politechnika Wrocławska, Wydział Chemiczny

CP protease of the O'nyong-nyong virus: substrate profiling, design and synthesis of inhibitors and activity-based probe...

Call: OPUS 15 , Panel: NZ6

Principal investigator: dr hab. Marcin Sieńczyk

Politechnika Wrocławska

Organometallic compounds as selective inhibitors of selected multidrug resistance proteins

Call: OPUS 15 , Panel: ST5

Principal investigator: dr hab. Damian Nestor Plażuk

Uniwersytet Łódzki, Wydział Chemii

Toward understanding allosteric regulation of the proteasome activity

Call: OPUS 1 , Panel: ST5

Principal investigator: dr hab. Elżbieta Jankowska

Uniwersytet Gdański, Wydział Chemii

Polymeric inhibitors of Zika virus

Call: OPUS 14 , Panel: ST5

Principal investigator: prof. Maria Nowakowska

Uniwersytet Jagielloński, Wydział Chemii

Inhibitors of BTLA-HVEM complex formation as potential targets for cancer immunotheraphy

Call: SONATA 13 , Panel: ST5

Principal investigator: dr Marta Marcelina Spodzieja

Uniwersytet Gdański, Wydział Chemii

Small-molecule inhibitors for characterization of the interaction between extracellular domains of Programmed Cell Death...

Call: MAESTRO 9 , Panel: ST5

Principal investigator: prof. Tadeusz Andrzej Holak

Uniwersytet Jagielloński, Wydział Chemii

Aminophosphonates bearing fluorine atoms as inhibitors odf aminopeptideses and their potential application for determina...

Call: HARMONIA 9 , Panel: ST5

Principal investigator: prof. Paweł Kazimierz Kafarski

Politechnika Wrocławska

Design of new small molecular regulators (inhibitors, activators) of the catalytic activity of adenylate kinases. Molecu...

Call: OPUS 13 , Panel: ST4

Principal investigator: dr Anna Kozakiewicz-Piekarz

Uniwersytet Mikołaja Kopernika w Toruniu, Wydział Chemii

Synthesis of 2-phosphonocarboxylates as potential covalent inhibitors of Rab geranylgeranyl transferase

Call: PRELUDIUM 12 , Panel: ST5

Principal investigator: Joanna Natalia Małolepsza

Politechnika Łódzka, Wydział Chemiczny

Allosteric inhibitors of proteasome - optimization of the structure of PR39 analogs in order to achieve greater efficien...

Call: PRELUDIUM 12 , Panel: ST5

Principal investigator: Małgorzata Giżyńska

Uniwersytet Gdański, Wydział Chemii

Electrochemical analysis of the corrosion process of Al2Cu intermetallic phase in the acidic solutions, in the presence ...

Call: SONATA 12 , Panel: ST5

Principal investigator: dr Przemysław Szczepan Kwolek

Politechnika Rzeszowska im. Ignacego Łukasiewicza, Wydział Budowy Maszyn i Lotnictwa

Novel multi-target directed ligands combining cholinesterase inhibition and 5-HT6 antagonism - design, synthesis and pha...

Call: SONATA 12 , Panel: NZ7

Principal investigator: dr hab. Anna Karolina Więckowska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Anticancer activity of novel tubulin polymerization inhibitors obtained by the chemical modification of colchicine

Call: OPUS 11 , Panel: ST5

Principal investigator: dr hab. Adam Włodzimierz Huczyński

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

Development of protocol for in silico design of compounds inhibit Ebola virus infection

Call: PRELUDIUM 11 , Panel: NZ2

Principal investigator: Dawid Zdzisław Warszycki

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Functional carbon based coatings on titanium substrate, modified by laser ablation designed for the integration with car...

Call: PRELUDIUM 11 , Panel: ST8

Principal investigator: Klaudia Krystyna Trembecka-Wójciga

Instytut Metalurgii i Inżynierii Materiałowej im. Aleksandra Krupkowskiego Polskiej Akademii Nauk

Discovery and development of small-molecule inhibitors of USP2 for targeted, non-genotoxic therapy of cancer

Call: OPUS 1 , Panel: ST5

Principal investigator: prof. Tadeusz Andrzej Holak

Uniwersytet Jagielloński, Wydział Chemii

Design, synthesis and biological evaluation of the new steroid sulfatase (STS) inhibitors based on sulfamate analogs con...

Call: PRELUDIUM 10 , Panel: NZ7

Principal investigator: Mateusz Daśko

Politechnika Gdańska, Wydział Chemiczny

Synthesis of new glutamate receptors antagonists and extensive investigation of their effect on tumor cells in the prese...

Call: OPUS 9 , Panel: ST5

Principal investigator: prof. Maria Wanda Bretner

Politechnika Warszawska, Wydział Chemiczny

New MOF compounds as degradable nanocontainers of tyrosine kinases inhibitors in novel anti-cancer therapy

Call: OPUS 9 , Panel: ST5

Principal investigator: prof. Artur Piotr Terzyk

Uniwersytet Mikołaja Kopernika w Toruniu, Wydział Chemii

Covalent inhibiors of bacterial ureases - design, activity and mode of binding

Call: PRELUDIUM 9 , Panel: NZ1

Principal investigator: dr Katarzyna Magdalena Macegoniuk

Politechnika Wrocławska, Wydział Chemiczny