Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Polymeric inhibitors of Zika virus

2017/27/B/ST5/01108

Keywords:

Zika virus inhibitor polyelectrolytes conjugates antiviral activity

Descriptors:

  • ST5_21:
  • ST5_11: Smart materials – self assembled materials, external stimuli-responsive materials
  • ST5_25:

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Uniwersytet Jagielloński, Wydział Chemii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Maria Nowakowska 

Number of co-investigators in the project: 6

Call: OPUS 14 - announced on 2017-09-15

Amount awarded: 1 769 200 PLN

Project start date (Y-m-d): 2018-07-26

Project end date (Y-m-d): 2024-01-25

Project duration:: 66 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (7)
  • Articles in post-conference publications (1)
  1. Self-Organized Nanoparticles of Random and Block Copolymers of Sodium 2-(acrylamido)-2-methyl-1-propanesulfonate and Sodium 11-(acrylamido)undecanoate as Safe and Effective Zika Virus Inhibitors
    Authors:
    Pawel Botwina, Magdalena Obłoza, Maria Zatorska-Płachta, Kamil Kamiński, Masanobu Mizusaki, Shin-Ichi Yusa, Krzysztof Szczubiałka, Krzysztof Pyrć* and Maria Nowakowska*
    Academic press:
    Pharmaceutics (rok: 2022, tom: 14, strony: 45309), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/pharmaceutics14020309 - link to the publication
  2. Curcumin-Poly(sodium 4‐styrenesulfonate) Conjugates as Potent Zika Virus Entry Inhibitors
    Authors:
    Magdalena Obłoza, Aleksandra Milewska, Paweł Botwina, Artur Szczepański, Aneta Medaj, Piotr Bonarek, Krzysztof Szczubiałka, Krzysztof Pyrć and Maria Nowakowska
    Academic press:
    ACS Appl. Mater. Interfaces (rok: 2024, tom: 16, strony: 5426−5437 (+Sup. Info)), Wydawca: American Chemical Society (ACS),
    Status:
    Published
    DOI:
    10.1021/acsami.3c13893 - link to the publication
  3. In Vitro Inhibition of Zika Virus Replication with Poly(Sodium 4-Styrenesulfonate)
    Authors:
    Paweł Botwina, Magdalena Obłoza, Artur Szczepański, Krzysztof Szczubiałka, Maria Nowakowska, Krzysztof Pyrć
    Academic press:
    Viruses (rok: 2020, tom: 12, strony: 14), Wydawca: Multidisciplinary Digital Publishing Institute
    Status:
    Published
    DOI:
    10.3390/v12090926 - link to the publication
  4. Polymers as Candidates for Broad Spectrum Antivirals - in Vitro Inhibition of Zika Virus with Sodium Polyanethole Sulfonate
    Authors:
    Magdalena Obłoza, Aleksandra Milewska, Paweł Botwina , Magdalena Górecka Artur Szczepański, Aneta Medaj, Piotr Bonarek , Krzysztof Szczubiałka, Krzysztof Pyrć, Maria Nowakowska
    Academic press:
    Polymers for Advanced Technologies (rok: 2024, tom: Jubileuszowy- dedykowany Panu, strony: ), Wydawca: Wiley
    Status:
    Accepted for publication
    DOI:
    brak - link to the publication
  5. Polimerowe inhibitory wirusów
    Authors:
    Maria Nowakowska, Krzysztof Pyrć, Krzysztof Szczubiałka
    Academic press:
    Alma Mater (rok: 2021, tom: 225, strony: 92-96), Wydawca: Uniwersytet Jagielloński
    Status:
    Published
    DOI:
    brak - link to the publication
  6. Reversible rearrangement of the cellular cytoskeleton: A key to the broad-spectrum antiviral activity of novel amphiphilic polymers
    Authors:
    Agnieszka Dabrowska , Pawel Botwina , Emilia Barreto-Duran , Agata Kubisiak , Magdalena Obloza , Aleksandra Synowiec , Artur Szczepanski , Marta Targosz-Korecka , Krzysztof Szczubialka , Maria Nowakowska , Krzysztof Pyrc
    Academic press:
    Materials Today Bio 22 (2023) 100763 (rok: 2023, tom: 22, strony: 100763 (14 stron +Sup. Info.)), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.mtbio.2023.100763 - link to the publication
  7. Poly(ethylene glycol)-block-poly(sodium 4‑styrenesulfonate) Copolymers as Efficient Zika Virus Inhibitors: In Vitro Studies
    Authors:
    Paweł Botwina, Magdalena Obłoza, Piotr Bonarek, Krzysztof Szczubiałka, Krzysztof Pyrć,* Maria Nowakowska*
    Academic press:
    ACS Omega (rok: 2023, tom: 8, strony: 6875–6883), Wydawca: ACS
    Status:
    Published
    DOI:
    10.1021/acsomega.2c07610 - link to the publication
  1. Potent Inhibition of Zika Virus Replication by Curcumin—Poly(sodium 4-styrenesulfonate) Conjugates
    Authors:
    Magdalena Obłoza*, Paweł Botwina, Gabriela Czerwonka, Krzysztof Szczubiałka, Krzysztof Pyrc and Maria Nowakowska
    Conference:
    1st International Electronic Conference on Pharmaceutics (rok: 2020, ), Wydawca: MDPI
    Data:
    konferencja 1-15 Dec
    Status:
    Published

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