Search results

151. Identification of Saccharomyces cerevisiae genes maintaining cell diploidy and genome stability

Principal investigator: dr hab. Adrianna Martyna Skoneczna

Instytut Biochemii i Biofizyki PAN

Call: OPUS 2, Panel: NZ2

152. Bridging the gap: DNA catalysis explained

Principal investigator: dr Maria Almudena Ponce Salvatierra

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Call: SONATA 14, Panel: NZ2

153. The G231N, E232T, N235D polymorphism in peptidylarginine deiminase gene from P. gingivalis: a novel factor of virulence …

Principal investigator: dr hab. Katarzyna Maria Gawron

Śląski Uniwersytet Medyczny w Katowicach

Call: OPUS 15, Panel: NZ2

154. Developement of new methods for designing RNA molecules that fold into desired spatial structures and their use for deve…

Principal investigator: prof. Janusz Marek Bujnicki

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Call: OPUS 13, Panel: NZ2

155. Identification of new genetic alterations in high grade paediatric brain tumours using next generation sequencing and ev…

Principal investigator: dr Joanna Trubicka

INSTYTUT - POMNIK - CENTRUM ZDROWIA DZIECKA

Call: OPUS 12, Panel: NZ2

156. A virtual screening protocol based on automatically generated structure-based pharmacophore models.

Principal investigator: Stefan Mateusz Mordalski

Instytut Farmakologii PAN

Call: HARMONIA 7, Panel: NZ2

157. CDKG/Ph1: is there a common process that regulates genomic stability in the grass species?

Principal investigator: prof. Robert Hasterok

UNIWERSYTET ŚLĄSKI, Wydział Nauk Przyrodniczych

Call: HARMONIA 6, Panel: NZ2

158. The mechanism of ligand binding and the conformational changes in the beta2-adrenergic receptor molecule

Principal investigator: dr Anita Płazińska

Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny z Oddziałem Analityki Medycznej

Call: SONATA 5, Panel: NZ2

159. Identification on novel copy-number variations (CNVs) in patients affected by bilateral congenital limb malformations by…

Principal investigator: dr hab. Aleksander Marian Jamsheer

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski I; Katedra i Zakład Genetyki Medycznej

Call: SONATA 2, Panel: NZ2

160. Organisation and Evolution of the Eukaryotic Centromeric Sequences

Principal investigator: dr Piotr Włodzimierz

Instytut Biochemii i Biofizyki PAN

Call: SONATINA 8, Panel: NZ2

161. Are phage introns a gap in our knowledge?

Principal investigator: dr Jakub Barylski

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Call: SONATA BIS 13, Panel: NZ2

162. Exposing unseen passages - towards identification of functional transient tunnels in protein structures

Principal investigator: dr hab. Jan Brezovský

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Call: PRELUDIUM BIS 5, Panel: NZ2

163. Multi-scale method for amyloid fibril assembly using protofilament structures predicted by coarse-grained docking simula…

Principal investigator: dr Michał Koliński

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: OPUS 22, Panel: NZ2

164. Integrative methods for modeling protein-protein complexes and multimolecular assemblies

Principal investigator: prof. Sebastian Kmiecik

Uniwersytet Warszawski, Centrum Nauk Biologiczno-Chemicznych

Call: SHENG 2, Panel: NZ2

165. Development of a new protein-protein docking method based on the flexible docking of short peptide fragments.

Principal investigator: dr Mateusz Kurciński

Uniwersytet Warszawski

Call: OPUS 17, Panel: NZ2

166. Identification of biomolecules released by colorectal cancer cells and detected in serum or/and exosomes

Principal investigator: dr hab. Anna Wojakowska

Instytut Chemii Bioorganicznej PAN

Call: SONATA 13, Panel: NZ2

167. The contribution of repetitive DNA, including transposable elements in the evolution of permanent translocation heterozy…

Principal investigator: dr hab. Hieronim Golczyk

Katolicki Uniwersytet Lubelski Jana Pawła II, Wydział Biotechnologii i Nauk o Środowisku

Call: OPUS 10, Panel: NZ2

168. Mechanism controlling cell fate decision in response to stress. Experimental and theoretical analysis.

Principal investigator: prof. Tomasz Lipniacki

Instytut Podstawowych Problemów Techniki Polska Akademia Nauk

Call: OPUS 7, Panel: NZ2

169. Structural investigation of the active center of gamma-secretase and its interactions with selected substrates.

Principal investigator: Krzysztof Młynarczyk

Uniwersytet Warszawski, Wydział Chemii

Call: PRELUDIUM 5, Panel: NZ2

170. Development of a tool for automatic evaluation of complexes of ligands with serotonin receptors based on the application…

Principal investigator: Sabina Marta Podlewska

Instytut Farmakologii PAN

Call: PRELUDIUM 5, Panel: NZ2

171. Structural RNomics

Principal investigator: prof. Janusz Marek Bujnicki

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Call: MAESTRO 2, Panel: NZ2

172. New bioinformatics method for predicting ligand-binding sites in RNA structures

Principal investigator: dr Anna Philips

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Call: PRELUDIUM 2, Panel: NZ2

173. Evolution of genes of Marek's disease virus associated with oncogenenicity.

Principal investigator: prof. Elżbieta Anna Samorek-Salamonowicz

Państwowy Instytut Weterynaryjny - Państwowy Instytut Badawczy

Call: OPUS 1, Panel: NZ7

174. Evaluation of peroxiredoxins 1 and 2 along with the thioredoxin-thioredoxin reductase system as new therapeutic targets …

Principal investigator: dr hab. Radosław Zagożdżon

Warszawski Uniwersytet Medyczny, I Wydział Lekarski

Call: OPUS 4, Panel: NZ7

175. Effect of dietary modulation of RAGE/AGE axis on prostatic neuroendocrine differentiation and the efficacy of anticancer…

Principal investigator: dr Wawrzyniec Dobrucki

Gdański Uniwersytet Medyczny

Call: OPUS 29, Panel: NZ7

176. Pharmacokinetic and pharmacodynamics modeling of antidepressants in a mechanistic approach for efficient therapy.

Principal investigator: prof. Filip Rybakowski

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Call: OPUS 29, Panel: NZ7

177. suPAR in older adults – a new biomarker of inflammageing, sarcopenia, and malnutrition?

Principal investigator: Karolina Agnieszka Dzięcioł

Uniwersytet Medyczny w Łodzi

Call: PRELUDIUM 24, Panel: NZ7

178. Photodynamic inactivation as a broad-spectrum antibiotic adjuvant reversing multidrug-resistant Gram-negative critical p…

Principal investigator: dr hab. Mariusz Stanisław Grinholc

Uniwersytet Gdański

Call: OPUS 29, Panel: NZ7

179. Restoring Beta-cell Integrity through Targeted SPOP Inhibition and PDX-1 Preservation

Principal investigator: dr Anna Czarna

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

Call: OPUS 26 (LAP), Panel: NZ7

180. First-in-class dual modulators of necroptosis kinases and 5-HT6 receptors as an innovative approach to develop an effect…

Principal investigator: prof. Jadwiga Handzlik

Uniwersytet Jagielloński, Collegium Medicum

Call: OPUS 26, Panel: NZ7

181. Integrated multi-omics approach to accelerate anticancer drug discovery by targeting metabolic reprogramming in human co…

Principal investigator: dr hab. Danuta Dudzik

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

Call: OPUS 26, Panel: NZ7

182. Directed screening and evaluation of novel bactericidal compounds active againsttubercle bacilli and Mycobacterium absce…

Principal investigator: prof. Jarosław Dziadek

Instytut Biologii Medycznej PAN

Call: OPUS 25, Panel: NZ7

183. Blood plasma microRNA profile as a basis for detecting Alzheimer's disease and dementia risk in pre-symptomatic individu…

Principal investigator: prof. Urszula Wojda

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: OPUS 24, Panel: NZ7

184. The impact of physical activity on brain resilience to chronic stress and the mediating role of blood-brain barrier.

Principal investigator: dr Marta Maria Nowacka-Chmielewska

Akademia Wychowania Fizycznego im. Jerzego Kukuczki w Katowicach, Instytut Fizjoterapii i Nauk o Zdrowiu

Call: OPUS 24, Panel: NZ7

185. The assessment of purity and identity confirmation of extracellular vesicles withcapillary electrophoresis

Principal investigator: Aleksandra Steć

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

Call: PRELUDIUM 21, Panel: NZ7

186. The interplay of neurochemistry and cancer biology: in the search for novel glioblastoma multiforme therapy among dopami…

Principal investigator: dr Katarzyna Maria Kucwaj-Brysz

Uniwersytet Jagielloński, Collegium Medicum

Call: SONATA 17, Panel: NZ7

187. New graphene-based approach targeting the prion-like propagation of α-synuclein in Parkinson's disease.

Principal investigator: dr hab. Małgorzata Kujawska

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Call: SONATA BIS 11, Panel: NZ7

188. Blocking the TNF-TNFR2 interactions as a novel approach to the ovarian carcinoma treatment

Principal investigator: prof. Sylwia Anna Rodziewicz-Motowidło

Uniwersytet Gdański, Wydział Chemii

Call: OPUS 21, Panel: NZ7

189. New 5-HT6 receptor ligands from the group of sulfonamide derivatives of cyclic arylguanidines in the treatment of gliobl…

Principal investigator: dr Przemysław Patryk Zaręba

Politechnika Krakowska im. Tadeusza Kościuszki, Wydział Inżynierii i Technologii Chemicznej

Call: PRELUDIUM 19, Panel: NZ7

190. New steroid sulfatase inhibitors based on 1,2,4-oxadiazole sulfamate derivatives

Principal investigator: Karol Andrzej Biernacki

Politechnika Gdańska, Wydział Chemiczny

Call: PRELUDIUM 19, Panel: NZ7

191. Seeking for CB1 and CB2 receptor ligands among drugs, drug metabolites, and phytochemical compounds

Principal investigator: Adam Stasiulewicz

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Call: PRELUDIUM 18, Panel: NZ7

192. Novel human topoisomerase II inhibitors as anticancer agents

Principal investigator: dr Barbara Kaproń

Uniwersytet Medyczny w Lublinie, Wydział Nauk o Zdrowiu

Call: PRELUDIUM 15, Panel: NZ7

193. Novel multi-target ligands of aminergic GPCRs as pharmacological tools to study the pathomechanism of schzophrenia

Principal investigator: dr hab. Agnieszka Anna Kaczor

Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny

Call: OPUS 14, Panel: NZ7

194. Modeling of quantitative structure-metabolic stability relationships as a tool to improve design of potential novel anti…

Principal investigator: prof. Tomasz Bączek

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

Call: OPUS 12, Panel: NZ7

195. Multifunctional inhibitors of beta-secretase with anti-aggregating properties of neurotoxic peptides - beta-amyloid and …

Principal investigator: prof. Barbara Antonina Malawska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: OPUS 11, Panel: NZ7

196. Quantitative model for predicting CYP inhibition parameters for novel arylpiperazine derivatives.

Principal investigator: dr Szymon Ulenberg

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

Call: PRELUDIUM 9, Panel: NZ7

197. Altered interaction between NMDA receptor subunits and their scaffolding proteins as a critical step to control drug see…

Principal investigator: prof. Małgorzata Maria Filip

Instytut Farmakologii PAN

Call: OPUS 9, Panel: NZ7

198. Effect of physical processes and excipients on properties of poorly water-soluble active pharmaceutical ingredients

Principal investigator: prof. Marian Wilhelm Paluch

UNIWERSYTET ŚLĄSKI, Wydział Nauk Ścisłych i Technicznych

Call: SYMFONIA 3, Panel: NZ7

199. New anti-leukemia drugs - advanced preclinical studies.

Principal investigator: prof. Urszula Wojda

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: OPUS 8, Panel: NZ7

200. The new homology model of H3 histaminic receptor - structure, interaction with ligand

Principal investigator: Jakub Józef Jończyk

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: PRELUDIUM 8, Panel: NZ7

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