Developement of new methods for designing RNA molecules that fold into desired spatial structures and their use for development of new functional RNAs and for prediction of noncoding RNAs in transcriptome sequences.
2017/25/B/NZ2/01294
Keywords
Descriptors
- NZ2_7: Bioinformatyka
- ST6_13: Bioinformatyka, bioobliczenia, obliczenia DNA i molekularne
- NZ1_4: Biologia strukturalna
Panel
NZ2 – Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology
Host institution
Międzynarodowy Instytut Biologii Molekularnej i Komórkowej
Voivodeship: mazowieckie
Principal investigator (from the host institution)
Number of co-investigators in the project: 5
Call
OPUS 13 – announced on 2017-03-15
- Amount awarded
- 1 494 250 PLN
- Project start date
- 2018-04-03
- Project end date
- 2021-12-02
- Project duration
- 44 months (the same as in the proposal)
- Project status
- Project settled
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
Publication in academic press/journals (2)
-
DesiRNA: structure-based design of RNA sequences with a replica exchange Monte Carlo approach
- Authors:
- Wirecki TK, Lach G ,Badepally NG ,Moafinejad SN ,Jaryani F ,Klaudel G ,Nec K ,Baulin EF ,Bujnicki JM
- Academic press:
- Nucleic Acid Research (year: 2025, volume: 53, pages: N/A), Publisher: Oxford University Press
- Status:
- Published
- DOI:
- 10.1093/nar/gkae1306 – link to the publication
-
RNAProbe: a web server for normalization and analysis of RNA structure probing data
- Authors:
- Wirecki TK, Merdas K, Bernat A, Boniecki MJ, Bujnicki JM, Stefaniak F
- Academic press:
- Nucleic Acids Research (year: 2020, volume: Vol. 48, pages: W292–W299), Publisher: Oxford University Press
- Status:
- Published
- DOI:
- 10.1093/nar/gkaa396 – link to the publication
Book publications / chapters in book publications (2)
-
Computational modeling methods for 3D structure prediction of ribozymes
- Authors:
- Ghosh P, Nithin C, Astha, Stefaniak F, Wirecki TK, Bujnick JM Editors: Mueller S, Masquida B and Winkler W
- Book:
- Ribozymes (year: 2020, volume: NA, pages: NA), Publisher: Wiley-VCH
- Status:
- Published
-
Modeling of three-dimensional RNA structures using SimRNA
- Authors:
- Wirecki TK, Nithin C, Mukherjee S, Bujnicki JM, Bonieck MJ
- Book:
- Protein Structure Prediction (4th edition) (year: 2020, volume: NA, pages: NA), Publisher: Springer
- Status:
- Published