Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Identification of Saccharomyces cerevisiae genes maintaining cell diploidy and genome stability

2011/03/B/NZ2/00293

Keywords:

ploidy level control genome instability Mitotic checkpoint 'barcode' array functional genomics

Descriptors:

  • NZ2_1: Molecular genetics
  • NZ2_2: Genomics, transcriptomics, epigenomics
  • NZ1_1: Molecular biology

Panel:

NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution :

Instytut Biochemii i Biofizyki PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Adrianna Skoneczna 

Number of co-investigators in the project: 7

Call: OPUS 2 - announced on 2011-09-15

Amount awarded: 416 190 PLN

Project start date (Y-m-d): 2012-08-06

Project end date (Y-m-d): 2016-08-05

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Dostęp do bazy danych Biobase (27 000 PLN)
  2. Program Origin Pro 2015.
  3. pH-metr z elektrodą (4 000 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (7)
  1. Mitochondria-Nucleus Network for Genome Stability.
    Authors:
    Kaniak-Golik Aneta i Skoneczna Adrianna
    Academic press:
    Free Radical Biology and Medicine (rok: 2015, tom: 82, strony: 73-104), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.freeradbiomed.2015.01.013 - link to the publication
  2. A Genomic screen revealing the importance of vesicular trafficking pathways in genome maintenance and protection against genotoxic stress in diploid Saccharomyces cerevisiae cells.
    Authors:
    Krol Kamil, Brozda Izabela, Skoneczny Marek, Bretner Maria, Skoneczna Adrianna
    Academic press:
    PLoS One (rok: 2015, tom: 10(3), strony: e0120702), Wydawca: plos.org
    Status:
    Published
    DOI:
    10.1371/journal.pone.0120702 - link to the publication
  3. Genetic instability in budding and fission yeast-sources and mechanisms
    Authors:
    Skoneczna A, Kaniak A, Skoneczny M.
    Academic press:
    FEMS Microbiology Reviews (rok: 2015, tom: 39, strony: 917-967), Wydawca: Oxford University Press
    Status:
    Published
    DOI:
    10.1093/femsre/fuv028 - link to the publication
  4. Ribosomal DNA status inferred from DNA cloud assays and mass spectrometry identification of agarose-squeezed proteins interacting with chromatin (ASPIC-MS)
    Authors:
    Krol K, Jendrysek J, Debski J, Skoneczny M, Kurlandzka A, Kaminska J, Dadlez M, Skoneczna A.
    Academic press:
    Oncotarget (rok: 2017, tom: 8(15), strony: 24988-25004), Wydawca: Albany, N.Y. : Impact Journals
    Status:
    Published
    DOI:
    10.18632/oncotarget.15332 - link to the publication
  1. Genomic screen for mutations conferring zeocin hypersensitivity reveals diverse roles of ves icular trafficking paths in genotoxic stress protection and in genome preservation.
    Authors:
    Król Kamil, Brózda Izabela, Skoneczny Marek, Bretner Maria, Skoneczna Adrianna
    Conference:
    Yeast Genetics Meeting (rok: 2014, ), Wydawca: Genetics Society of America
    Data:
    konferencja 29.07- 3.08.2014
    Status:
    Published
  2. Saccharomyces cerevisiae cells lacking SWI6 gene present symptomps of genome instability phenotype
    Authors:
    Brózda I., Król K., Skoneczna A., Skoneczny M.
    Conference:
    11th International Conference on Environmental Mutagenesis, XI Congress of SBMCTA and IX Congress of ALAMCTA, Foz do Iguaçu, Brazil, 3-8 November 2013. (rok: 2013, ), Wydawca: x
    Data:
    konferencja 3-8.11.2013
    Status:
    Published
  3. The dark side of Swi6; genomic screen for mutants hypersensitive to double strand breaks reveals Swi6 indispensability for genome integrity and maintaining of cellular ploidy.
    Authors:
    Brózda Izabela, Adamus Paulina, Król Kamil, Skoneczny Marek, Skoneczna Adrianna
    Conference:
    Yeast Genetics Meeting (rok: 2014, ), Wydawca: Genetics Society of America
    Data:
    konferencja 29.07-3.08.2014
    Status:
    Published
  4. Vesicular transport is implicated in the cellular response to DNA double strand breaks in Saccharomyces cerevisiae.
    Authors:
    Król K., Brózda I., Skoneczna A., Skoneczny M.
    Conference:
    11th International Conference on Environmental Mutagenesis, XI Congress of SBMCTA and IX Congress of ALAMCTA, Foz do Iguaçu, Brazil (rok: 2013, ), Wydawca: x
    Data:
    konferencja 3-8.11.2013
    Status:
    Published
  5. rDNA status inferred from DNA cloud assays and mass spectrometry identification of agarose squeezed DNA-bound proteins
    Authors:
    Kamil Krol, Jendrysek J., Debski J., Skoneczny M., Kurlandzka A., Kaminska J., Suski C., Dadlez M., Skoneczna A.
    Conference:
    V Polski Kongres Genetyki (rok: 2016, ), Wydawca: PTG i PTGC
    Data:
    konferencja 19-22 września 2016
    Status:
    Published
  6. Cellular response to DSB stress encompasses vesicular transport and cell cycle guardians.
    Authors:
    Skoneczna A., Brózda I., Król K., Skoneczny M.
    Conference:
    26th International Conference of Yeast Genetics and Molecular Biology, Frankfurt/Main, Germany. (rok: 2013, ), Wydawca: Wiley Blackwell
    Data:
    konferencja 29.08–3.09.2013
    Status:
    Published
  7. The Saccharomyces cerevisiae Swi6 is a genome maintenance protein, requiredespecially after DSB stress
    Authors:
    SKONECZNA A., KRÓL K., JENDRYSEK J., KURDZIEL J., BRÓZDA I., ADAMUS P., SKONECZNY M.
    Conference:
    27th International Conference on Yeast Genetics and Molecular Biology (ICYGMB) (rok: 2015, ), Wydawca: Wiley
    Data:
    konferencja 6-12 września 2015
    Status:
    Published