Projects funded by the NCN


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The G231N, E232T, N235D polymorphism in peptidylarginine deiminase gene from P. gingivalis: a novel factor of virulence and prognosis in periodontitis

2018/29/B/NZ2/01930

Keywords:

gene polymorphism molecular genetics peptidylarginine deiminase periodontal disease

Descriptors:

  • NZ2_1:
  • NZ2_4:
  • NZ2_6:

Panel:

NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution :

Śląski Uniwersytet Medyczny w Katowicach

woj. śląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Katarzyna Maria Gawron 

Number of co-investigators in the project: 5

Call: OPUS 15 - announced on 2018-03-15

Amount awarded: 1 645 022 PLN

Project start date (Y-m-d): 2019-01-02

Project end date (Y-m-d): 2024-01-01

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (5)
  1. Metabolomic Status of The Oral Cavity in Chronic Periodontitis.
    Authors:
    Gawron K., Wojtowicz W., Łazarz-Bartyzel K., Łamasz A., Qasem B., Mydel P., Chomyszyn-Gajewska M., Potempa J., Mlynarz P.
    Academic press:
    In Vivo (rok: 2019, tom: 33(4), strony: 1165-1174), Wydawca: INTERNATIONAL INSTITUTE OF ANTICANCER RESEARCH, ATHENS, GREECE
    Status:
    Published
    DOI:
    10.21873/invivo.11587 - link to the publication
  2. Host and bacterial factors linking periodontitis and rheumatoid arthritis.
    Authors:
    Krutyhołowa A., Strzelec K., Dziedzic A., Bereta G.P., Łazarz-Bartyzel K., Potempa J. and Gawron K.
    Academic press:
    Frontiers in Immunology (rok: 2022, tom: 13, strony: 17), Wydawca: FRONTIERS MEDIA SA, LAUSANNE, SWITZERLAND
    Status:
    Published
    DOI:
    10.3389/fimmu.2022.980805 - link to the publication
  3. Identification of a new genetic variant (G231N, E232T, N235D) of peptidylarginine deiminase from P. gingivalis in advanced periodontitis.
    Authors:
    Bereta G.P., Strzelec K., Łazarz-Bartyzel K., Dziedzic-Kowalska A., Nowakowska Z.M., Krutyhołowa A., Bielecka E., Kantyka T., Grabiec A.M., Kaczmarzyk T., Chomyszyn-Gajewska M., Potempa J., Gawron K.
    Academic press:
    Frontiers in Immunology (rok: 2024, tom: 15, strony: 13), Wydawca: FRONTIERS MEDIA SA, LAUSANNE, SWITZERLAND
    Status:
    Published
    DOI:
    10.3389/fimmu.2024.1355357 - link to the publication
  4. HDAC3 Regulates Gingival Fibroblast Inflammatory Responses in Periodontitis.
    Authors:
    Lagosz K.B., Bysiek A., Macina J.M., Bereta G.P., Kantorowicz M., Lipska W., Sochalska M., Gawron K., Kaczmarzyk T., Chomyszyn-Gajewska M., Fossati G., Potempa J., Grabiec A.M.
    Academic press:
    Journal of Dental Research (rok: 2020, tom: 99(1), strony: 98-106), Wydawca: SAGE PUBLICATIONS INC, CA 91320
    Status:
    Published
    DOI:
    10.1177/0022034519885088 - link to the publication
  5. Polymorphic Variants of Peptidylarginine Deiminase Gene from P. gingivalis-Searching for Targets for Supportive Therapy of Periodontitis.
    Authors:
    Strzelec K., Dziedzic-Kowalska A., Sieron Ł., Bereta G.P., Stepien K.L., Ferenc K., Łazarz-Bartyzel K., Olszewska-Czyż I., Rąpalska I., Aptekorz M., Kaczmarzyk T., Cześnikiewicz-Guzik M., Gawron K.
    Academic press:
    International Journal of Molecular Sciences (rok: 2025, tom: 26(4), strony: 23), Wydawca: MDPI, MDPI AG, Grosspeteranlage 5, CH-4052 BASEL, SWITZERLAND
    Status:
    Published
    DOI:
    10.3390/ijms26041662 - link to the publication