Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Mechanism controlling cell fate decision in response to stress. Experimental and theoretical analysis.

2014/13/B/NZ2/03840

Keywords:

innate immunity carcinogenesis epithelial-mesenchymal transformation autophagy cell fate decisions molecular noise single cell systmens biology

Descriptors:

  • NZ2_9: Systems biology
  • NZ2_8: Computational biology
  • NZ2_10: Biological systems analysis, modelling and simulation

Panel:

NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution :

Instytut Podstawowych Problemów Techniki PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Tomasz Lipniacki 

Number of co-investigators in the project: 7

Call: OPUS 7 - announced on 2014-03-17

Amount awarded: 887 016 PLN

Project start date (Y-m-d): 2015-01-22

Project end date (Y-m-d): 2019-01-21

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (12)
  1. Computation and measurement of cell decision making errors using single cell data
    Authors:
    Habibi I., Cheong R., Lipniacki T., Levchenko A., Emamian E.S., Abdi A.
    Academic press:
    PLOS COMPUTATIONAL BIOLOGY (rok: 2017, tom: 13, strony: e1005436-1-17), Wydawca: Public Library of Science
    Status:
    Published
    DOI:
    10.1371/journal.pcbi.1005436 - link to the publication
  2. SPATKIN: a simulator for rule-based modeling of biomolecular site dynamics on surfaces
    Authors:
    Kochańczyk M., Hlavacek W.S., Lipniacki T.
    Academic press:
    BIOINFORMATICS (rok: 2017, tom: 33, strony: 3667-3669), Wydawca: Oxford University Press
    Status:
    Published
    DOI:
    10.1093/bioinformatics/btx456 - link to the publication
  3. Effective reaction rates for diffusion-limited reaction cycles
    Authors:
    Nałęcz-Jawecki Paweł, Szymańska Paulina, Kochańczyk Marek, Miękisz Jacek, Lipniacki Tomasz
    Academic press:
    The Journal of Chemical Physics (rok: 2015, tom: 143, strony: 215102), Wydawca: American Institute of Physics
    Status:
    Published
    DOI:
    10.1063/1.4936131 - link to the publication
  4. Feedbacks, Bifurcations, and Cell Fate Decision-Making in the p53 System
    Authors:
    Beata Hat, Marek Kochańczyk, Marta N. Bogdał, Tomasz Lipniacki
    Academic press:
    PLoS Computational Biology (rok: 2016, tom: 12, strony: 1004787), Wydawca: Public Library of Science
    Status:
    Published
    DOI:
    10.1371/journal.pcbi.1004787 - link to the publication
  5. Importins promote high-frequency NF-κB oscillations increasing information channel capacity
    Authors:
    Zbigniew Korwek1, Karolina Tudelska , Paweł Nałęcz-Jawecki, Maciej Czerkies, Wiktor Prus, Joanna Markiewicz, Marek Kochańczyk, Tomasz Lipniacki1
    Academic press:
    Biology Direct (rok: 2016, tom: 0,500694444444444, strony: -), Wydawca: BioMed Central
    Status:
    Published
    DOI:
    10.1186/s13062-016-0164-z - link to the publication
  6. Polarization of concave domains by traveling wave pinning
    Authors:
    Białecki S., Kaźmierczak B., Lipniacki T.
    Academic press:
    PLOS ONE (rok: 2017, tom: 12, strony: e0190372), Wydawca: Public Library of Science
    Status:
    Published
    DOI:
    10.1371/journal.pone.0190372 - link to the publication
  7. Stationary waves on the sphere
    Authors:
    Sławomir Białecki, Bogdan Kaźmierczak, Je-Chian Tsai
    Academic press:
    SIAM Journal of Applied Mathematics (rok: 2015, tom: 75, strony: 1761–1788), Wydawca: Society for Industrial and Applied Mathematics
    Status:
    Published
    DOI:
    10.1137/140999384 - link to the publication
  8. RAF1/BRAF dimerization integrates the signal from RAS to ERK and ROKa
    Authors:
    Varga A., Ehrenreiter K., Aschenbrenner B., Kocieniewski P., Kochańczyk M., Lipniacki T., Baccarini M.
    Academic press:
    SCIENCE SIGNALING (rok: 2017, tom: 10, strony: aai8482-1-11), Wydawca: American Association for the Advancement of Science
    Status:
    Published
    DOI:
    10.1126/scisignal.aai8482 - link to the publication
  9. Relaxation oscillations and hierarchy of feedbacks in MAPK signaling
    Authors:
    Kochańczyk M., Kocieniewski P., Kozłowska E., Jaruszewicz-Błońska J., Sparta B., Pargett M., Albeck J.G., Hlavacek W.S., Lipniacki T.
    Academic press:
    SCIENTIFIC REPORTS (rok: 2017, tom: 7, strony: 38244, pp.1-15), Wydawca: Nature Publishing Group
    Status:
    Published
    DOI:
    10.1038/srep38244 - link to the publication
  10. Traveling waves in a coupled reaction–diffusion and difference model of hematopoiesis
    Authors:
    Adimy M, Chekroun A, Kaźmierczak B
    Academic press:
    Journal of Differential Equations (rok: 2017, tom: 262, strony: 4085–4128), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jde.2016.12.009 - link to the publication
  11. Eigenfunction Approach to Transient Patterns in a Model of Chemotaxis
    Authors:
    Paramita Chatterjee, Bogdan Kaźmierczak
    Academic press:
    Mathematical Modelling of Natural Phenomena (rok: 2016, tom: 11, strony: 44 - 62), Wydawca: EDP Sciences
    Status:
    Published
    DOI:
    10.1051/mmnp/201611204 - link to the publication
  12. Genetic toggle switch controlled by bacterial growth rate
    Authors:
    Jaruszewicz-Błońska J., Lipniacki T.
    Academic press:
    BMC SYSTEMS BIOLOGY (rok: 2017, tom: 11, strony: 117-1-11), Wydawca: BioMed Central
    Status:
    Published
    DOI:
    10.1186/s12918-017-0483-4 - link to the publication

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