Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Structural investigation of the active center of gamma-secretase and its interactions with selected substrates.

2013/09/N/NZ2/04404

Keywords:

gamma-secretase Alzheimer's disease molecular dynamics

Descriptors:

  • NZ2_8: Computational biology
  • NZ2_10: Biological systems analysis, modelling and simulation

Panel:

NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution :

Uniwersytet Warszawski, Wydział Chemii

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Krzysztof Młynarczyk 

Number of co-investigators in the project: 2

Call: PRELUDIUM 5 - announced on 2013-03-15

Amount awarded: 99 970 PLN

Project start date (Y-m-d): 2014-02-13

Project end date (Y-m-d): 2016-02-12

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (1)
  1. The Role of Cholesterol in Amyloidogenic Substrate Binding to the γ-Secretase Complex
    Authors:
    Urszula Orzeł, Jakub Jakowiecki, Krzysztof Młynarczyk, Sławomir Filipek
    Academic press:
    Biomolecules (rok: 2021, tom: 11, strony: 935), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/biom11070935 - link to the publication