Projects funded by the NCN


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39 projects found matching your search criteria :

  1. Next-generation sequencing of miRNA transcriptome and functional in vitro study: towards unravelling pathomechanisms and...

    Call: OPUS 8 , Panel: NZ2

    Principal investigator: prof. Michał Witt

    Instytut Genetyki Człowieka PAN

  2. L-asparaginase resistance in childhood ALL with IKZF1, TP53, BCR-ABL1 and iAMP21 alterations.

    Call: PRELUDIUM 7 , Panel: NZ5

    Principal investigator: Ewa Wrona

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  3. Mechanism of SYK-mediated suppression of differentiation and apoptosis in acute myeloid leukemia (AML)

    Call: PRELUDIUM 6 , Panel: NZ5

    Principal investigator: dr Anna Polak

    Instytut Hematologii i Transfuzjologii

  4. The regulation of vitamin D receptor expression by retinoids

    Call: PRELUDIUM 6 , Panel: NZ3

    Principal investigator: Aleksandra Marchwicka

    Uniwersytet Wrocławski, Wydział Biotechnologii

  5. Genetics of pediatric T-cell acute lymphoblastic leukemia

    Call: PRELUDIUM 6 , Panel: NZ5

    Principal investigator: Bronisława Szarzyńska-Zawadzka

    Instytut Genetyki Człowieka PAN

  6. The role of nucelophosmin-1 exon 12 abnormalities in acute myeloid leukemias and myelodyplastic syndrome

    Call: HARMONIA 5 , Panel: NZ5

    Principal investigator: dr hab. Krzysztof Giannopoulos

    Uniwersytet Medyczny w Lublinie, II Wydział Lekarski z Oddziałem Anglojęzycznym

  7. Investigation of the molecular mechanisms of anti-leukemic activity of SK053, a small molecule compound targeting enzyme...

    Call: SONATA BIS 3 , Panel: NZ5

    Principal investigator: prof. Dominika Nowis

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  8. Investigation of the role of ficolins in anti-microbial defense in patients suffering from acute myeloid leukaemia, unde...

    Call: PRELUDIUM 4 , Panel: NZ6

    Principal investigator: Anna Sokołowska

    Instytut Biologii Medycznej PAN

  9. Finding a role of LAT adaptor in development of T cell acute lymphoblastic leukemia (T-ALL)

    Call: OPUS 3 , Panel: NZ5

    Principal investigator: dr hab. Arkadiusz Miążek

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda PAN

  10. Late neuroanatomical and neuropsychological sequelae of central nervous system prophylaxis in children with acute lympho...

    Call: PRELUDIUM 3 , Panel: NZ5

    Principal investigator: dr Olga Zając-Spychała

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski I

  11. Search for biomarkers of CNS involvement and neurotoxicity in childhood acute lymphoblastic leukemia: a metabolomic anal...

    Call: OPUS 2 , Panel: NZ5

    Principal investigator: prof. Wojciech Młynarski

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski z Oddziałem Stomatologicznym

  12. Immune Surveillance in Pathogenesis and Clinical Outcome of Childhood Acute Lymphoblastic Leukemia - the Role of PRF1 Ge...

    Call: PRELUDIUM 2 , Panel: NZ5

    Principal investigator: Aleksandra Jasińska

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski z Oddziałem Stomatologicznym

  13. Exploring kinase hyperactivation as an innovative approach for chemo-immunotherapy for B cell acute lymphoblastic leukem...

    Call: PRELUDIUM BIS 5 , Panel: NZ7

    Principal investigator: dr hab. Małgorzata Firczuk

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

  14. Differences in the glycoproteomic profile of acute myeloid leukemia (AML) between cytogenetic and risk groups according ...

    Call: PRELUDIUM 22 , Panel: NZ5

    Principal investigator: Tomasz Pieńkowski

    Uniwersytet Medyczny w Białymstoku

  15. Heterogeneity immunocompetent cells during chimeric antigen receptor T cell (CAR-T) CD19 immunotherapy.

    Call: PRELUDIUM 22 , Panel: NZ6

    Principal investigator: Aleksandra Oszer

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  16. Investigating the mechanisms of CD20 downregulation triggered by tyrosine kinase inhibitors in Philadelphia chromosome-p...

    Call: PRELUDIUM 22 , Panel: NZ5

    Principal investigator: Krzysztof Domka

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

  17. Dissecting the regulatory interplay between proteases and protein kinases in acute lymphoblastic leukemia using mass cyt...

    Call: OPUS 24 , Panel: NZ5

    Principal investigator: dr hab. Marcin Poręba

    Politechnika Wrocławska

  18. Investigating the role of fibroblast growth factor receptors and STAT transcription factors in the targeted therapy of a...

    Call: PRELUDIUM BIS 4 , Panel: NZ5

    Principal investigator: prof. Ewa Marcinkowska

    Uniwersytet Wrocławski, Wydział Biotechnologii

  19. Unraveling genes and mechanisms underlying relapse of T-cell acute lymphoblastic leukemia

    Call: OPUS 24 , Panel: NZ5

    Principal investigator: dr hab. Małgorzata Dawidowska

    Instytut Genetyki Człowieka Polskiej Akademii Nauk

  20. Mechanisms and consequences of CD19 loss in B-acute lymphoblastic leukaemia patients relapsing after CD19-CAR-T cell the...

    Call: PRELUDIUM BIS 3 , Panel: NZ5

    Principal investigator: prof. Przemysław Juszczyński

    Instytut Hematologii i Transfuzjologii

  21. Inhibiting the Mitochondrial Intermembrane Space Assembly pathway as a newapproach to prevent metabolic reprogramming of...

    Call: OPUS 22 , Panel: NZ5

    Principal investigator: dr hab. Carlo Vascotto

    Instytut Hematologii i Transfuzjologii

  22. Assessment of SARS-CoV-2 infection in patients with chronic lymphocytic leukemia depending on indicators of immune disor...

    Call: OPUS 21 , Panel: NZ6

    Principal investigator: prof. Ewelina Grywalska

    Uniwersytet Medyczny w Lublinie

  23. Identification of mTOR pathway deregulation mechanisms alternative to mutations in T-cell acute lymphoblastic leukemia (...

    Call: PRELUDIUM 20 , Panel: NZ2

    Principal investigator: Natalia Maćkowska-Maślak

    Instytut Genetyki Człowieka Polskiej Akademii Nauk

  24. Array-based genomic and transcriptomic profiling in pediatric acute myeloblastic leukemia in search of genes resposible ...

    Call: SONATA 2 , Panel: NZ5

    Principal investigator: dr Joanna Szczepanek

    Uniwersytet Mikołaja Kopernika

  25. Improving therapeutic efficacy of anti-CD20 antibodies in precursor B-cell acute lymphoblastic leukemia

    Call: OPUS 18 , Panel: NZ5

    Principal investigator: dr Małgorzata Firczuk

    Warszawski Uniwersytet Medyczny, Wydzial Lekarski

  26. Epigenetic effect on therapeutic activities of all-trans-retinoic acid in acute myeloid leukemia

    Call: OPUS 17 , Panel: NZ5

    Principal investigator: prof. Arthur Zelent

    Wojskowy Instytut Higieny i Epidemiologii im. gen. Karola Kaczkowskiego

  27. Identifying and overcoming mechanisms promoting resistance to venetoclax in B cell acute lymphoblastic leukemia with MLL...

    Call: PRELUDIUM 16 , Panel: NZ5

    Principal investigator: dr Klaudyna Fidyt

    Warszawski Uniwersytet Medyczny, Wydział Lekarski

  28. Deciphering molecular mechanism of CDK8 kinase inhibitors action in acute myeloid leukemia

    Call: SONATA BIS 8 , Panel: NZ2

    Principal investigator: dr hab. Michał Mikula

    Narodowy Instytut Onkologii im. Marii Skłodowskiej-Curie - Państwowy Instytut Badawczy

  29. Tracing the roots of leukemia - how preleukemic hematopoietic stem cells contribute to acute lymphoid and myeloid leukem...

    Call: HARMONIA 10 , Panel: NZ5

    Principal investigator: dr Krzysztof Szade

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  30. Determining the role of basigin in multiple myeloma and acute myeloid leukaemia development

    Call: PRELUDIUM 15 , Panel: NZ5

    Principal investigator: Piotr Łacina

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  31. Effect of heterozygous mutations and radiaton on expression of DNA repair genes- MRE11, RAD50 and NBN in the cells of ac...

    Call: OPUS 1 , Panel: NZ5

    Principal investigator: prof. Jerzy Nowak

    Instytut Genetyki Człowieka PAN

  32. Identification of novel oncogenic/tumor suppressive miRNA-mRNA interactions in pathogenesis of pediatric T-cell acute ly...

    Call: PRELUDIUM 13 , Panel: NZ2

    Principal investigator: Monika Drobna-Śledzińska

    Instytut Genetyki Człowieka Polskiej Akademii Nauk

  33. Identification and targeting molecular drug resistance mechanisms in adult B-cell acute lymphoblastic leukemia

    Call: OPUS 1 , Panel: NZ4

    Principal investigator: dr hab. Przemysław Juszczyński

    Instytut Hematologii i Transfuzjologii

  34. Mediators of genetic instability in B-cell acute lymphoblastic leukemia (B-ALL)

    Call: PRELUDIUM 10 , Panel: NZ5

    Principal investigator: Karolina Karabin

    Warszawski Uniwersytet Medyczny, I Wydział Lekarski

  35. Products of DNA demethylation and deamination pathways as new biomarkers of development and predictors of the outcome in...

    Call: OPUS 10 , Panel: NZ5

    Principal investigator: dr hab. Daniel Gackowski

    Uniwersytet Mikołaja Kopernika, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy, Wydział Farmaceutyczny

  36. Novel pro-oxidative strategies in the treatment of B cell acute lymphoblastic leukemia

    Call: SONATA BIS 5 , Panel: NZ5

    Principal investigator: dr Małgorzata Firczuk

    Warszawski Uniwersytet Medyczny, Wydział Lekarski

  37. Genetic variability of transcription factor GATA3 in pathogenesis of acute limphoblastic leucemia (ALL)

    Call: PRELUDIUM 9 , Panel: NZ5

    Principal investigator: Joanna Madzio

    Uniwersytet Medyczny w Łodzi, I Katedra Pediatrii

  38. DNA methylation and microRNA expression profiling in different types of cancer

    Call: OPUS 1 , Panel: NZ4

    Principal investigator: dr hab. Izabela Zawlik

    Uniwersytet Rzeszowski

  39. Cardiovascular micro RNA fingerprint of anthracyclines - study in vitro and in vivo in long-term acute lymphoblastic leu...

    Call: SONATA 9 , Panel: NZ7

    Principal investigator: dr Justyna Totoń-Żurańska

    Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Lekarski