Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Genetic variability of transcription factor GATA3 in pathogenesis of acute limphoblastic leucemia (ALL)

2015/17/N/NZ5/00669

Keywords:

GATA3 acute limphoblastic leukemia BCR-ABL1-like ALL

Descriptors:

  • NZ2_1: Molecular genetics
  • NZ3_7: Signal transduction
  • NZ5_5: Diagnostics in human diseases

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Uniwersytet Medyczny w Łodzi, I Katedra Pediatrii

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Joanna Madzio 

Number of co-investigators in the project: 3

Call: PRELUDIUM 9 - announced on 2015-03-16

Amount awarded: 147 600 PLN

Project start date (Y-m-d): 2016-03-17

Project end date (Y-m-d): 2019-03-16

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (2)
  1. GATA3 germline variant is associated with CRLF2 expression and predicts outcome in pediatric B-cell precursor acute lymphoblastic leukemia.
    Authors:
    Joanna Madzio, Agata Pastorczak, Lukasz Sedek, Marcin Braun, Joanna Taha, Kamila Wypyszczak, Joanna Trelinska, Monika Lejman, Katarzyna Muszynska–Roslan, Bartlomiej Tomasik, Katarzyna Derwich, Andrzej Koltan, Bernarda Kazanowska, Nina Irga-Jaworska, Wanda Badowsk, Michal Matysiak, Jerzy Kowalczyk, Jan Styczynski, Wojciech Fendler, Tomasz Szczepanski, Wojciech Mlynarski
    Academic press:
    Genes, Chromosomes & Cancer (rok: 2019, tom: 4, strony: 45299), Wydawca: John Wiley & Sons
    Status:
    Published
    DOI:
    10.1002/gcc.22748 - link to the publication
  2. Selected miRNA levels are associated with IKZF1 microdeletions in pediatric acute lymphoblastic leukemia
    Authors:
    Jacek Krzanowski*, Joanna Madzio*, Agata Pastorczak, Adam Tracz, Marcin Braun, Jacek Tabarkiewicz, Andrzej Pluta , Wojciech Młynarski, Izabela Zawlik
    Academic press:
    ONCOLOGY LETTERS (rok: 2017, tom: 14, strony: 3853-3861), Wydawca: Spandidos Publications
    Status:
    Published
    DOI:
    10.3892/ol.2017.6599 - link to the publication

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